Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles

Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer ’s disease (AD). Recent evidence has suggested that ...

Source: BMC Cell Biology - July 30, 2020 Category: Cytology Authors: Allaura S. Cone, Stephanie N. Hurwitz, Gloria S. Lee, Xuegang Yuan, Yi Zhou, Yan Li and David G. Meckes Jr Tags: Research article Source Type: research