Localization-specific distributions of protein pI in human proteome are governed by local pH and membrane charge
Whole-proteome distributions of protein isoelectric point (pI) values in different organisms are bi- or trimodal with some variations. It was suggested that the observed multimodality of the proteome-wide pI d... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 20, 2019 Category: Cytology Authors: Atsushi Kurotani, Alexander A. Tokmakov, Ken-Ichi Sato, Vasily E. Stefanov, Yutaka Yamada and Tetsuya Sakurai Tags: Research article Source Type: research
In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants
HPV16 infection is one of the main risk factors involved in the development of cervical cancer, mainly due to the high oncogenic potential of the viral proteins E6 and E7, which are involved in the different p... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 19, 2019 Category: Cytology Authors: Hugo Alberto Rodr íguez-Ruiz, Olga Lilia Garibay-Cerdenares, Berenice Illades-Aguiar, Sarita Montaño, Xiaowei Jiang and Marco Antonio Leyva-Vázquez Tags: Research article Source Type: research
In silico evidence of de novo interactions between ribosomal and Epstein - Barr virus proteins
Association of Epstein-Barr virus (EBV) encoded latent gene products with host ribosomal proteins (RPs) has not been fully explored, despite their involvement in the aetiology of several human cancers. To gain... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 15, 2019 Category: Cytology Authors: Edmund Ui-Hang Sim and Shruti Prashant Talwar Tags: Research article Source Type: research
Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway
The PINK1:Parkin pathway regulates the autophagic removal of damaged and dysfunctional mitochondria. While the response of this pathway to complete loss of ΔΨm, as caused by high concentrations of mitochondria... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 14, 2019 Category: Cytology Authors: J. Logan Bowling, Mary Catherine Skolfield, Wesley A. Riley, Andrew P. Nolin, Larissa C. Wolf and David E. Nelson Tags: Research article Source Type: research
Isolation of fresh endothelial cells from porcine heart for cardiovascular studies: a new fast protocol suitable for genomic, transcriptomic and cell biology studies
Endothelial cells (ECs) play a key role in tissue homeostasis, in several pathological conditions, and specifically in the control of vascular functions. ECs are frequently used as in vitro model systems for c... (Source: BMC Cell Biology)
Source: BMC Cell Biology - August 13, 2019 Category: Cytology Authors: Olli-Pekka A. H ätinen, Johanna E. Lähteenvuo, Henna J. Korpela, Juho J. Pajula and Seppo Ylä-Herttuala Tags: Methodology article Source Type: research
