SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation

The platelet-derived growth factor (PDGF) family of ligands exerts their cellular effects by binding to α- and β-tyrosine kinase receptors (PDGFRα and PDGFRβ, respectively). SUMOylation is an important posttra...

Source: BMC Cell Biology - May 16, 2023 Category: Cytology Authors: Kehuan Wang, Natalia Papadopoulos, Anahita Hamidi, Johan Lennartsson and Carl-Henrik Heldin Tags: Research Source Type: research