Same Day Discharge Following Mastectomy and Immediate Tissue Expander Reconstruction: The Effect of Patient Expectations
Within, we compare the short-term outcomes of patients receiving same day mastectomy and tissue expander reconstruction for those discharged on postoperative day one versus those discharged immediately following surgery to explore the safety, efficacy, and potential impact on hospital processes. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - April 11, 2024 Category: Cosmetic Surgery Authors: Jordan Wiebe, Nikhi P. Singh, Steven Dawson, Jessica Berns, Connor Drake, Carla Fisher, Kandice Ludwig, Jason VonDerHaar, Mary E. Lester, Aladdin H. Hassanein Tags: Correspondence and Communications Source Type: research
Effects of Anterior Fundoplication on Postoperative Dysphagia and Reflux After Laparoscopic Esophagocardiomyotomy for Pediatric Achalasia
Conclusion: In this largest observation of pediatric achalasia patients, A-fundo appeared clinically insignificant when determining contributors to control GER or exacerbate postoperative dysphagia. A-fundo should not be routinely adopted in children having L-ECM for achalasia without further multicenter analysis but appears beneficial in cases having inadvertent mucosal violation.PMID:38597929 | DOI:10.1089/lap.2023.0415 (Source: Adv Data)
Source: Adv Data - April 10, 2024 Category: Epidemiology Authors: Mary Peyton French Jordan Busing Sari Acra Heidi Chen Laura Stafman Irving Zamora Michael Holzman Harold N Lovvorn Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Stem cell engineering approaches for investigating glial cues in central nervous system disorders
Curr Opin Biotechnol. 2024 Apr 9;87:103131. doi: 10.1016/j.copbio.2024.103131. Online ahead of print.ABSTRACTGlial cells are important in maintaining homeostasis for neurons in the central nervous system (CNS). During CNS disease or after injury, glia react to altered microenvironments and often acquire altered functions that contribute to disease pathology. A major focus for research is utilizing stem cell (SC)-derived glia as a potential renewable source for cell replacement to restore function, including neuronal support, and as a model for disease states to identify therapeutic targets. In this review, we focus on SC d...
Source: Current Opinion in Biotechnology - April 10, 2024 Category: Biotechnology Authors: Sangamithra Vardhan Tyler Jordan Shelly Sakiyama-Elbert Source Type: research
Assessing and managing the risk of < i > Aedes < /i > mosquito introductions via the global maritime trade network
by Janna R. Willoughby, Benjamin A. McKenzie, Jordan Ahn, Todd D. Steury, Christopher A. Lepzcyk, Sarah Zohdy
The global shipping network (GSN) has been suggested as a pathway for the establishment and reintroduction ofAedes aegypti andAedes albopictus primarily via the tire trade. We used historical maritime movement data in combination with an agent-based model to understand invasion risk in the United States Gulf Coast and how the risk of these invasions could be reduced. We found a strong correlation between the total number of cargo ship arrivals at each port and likelihood of arrival by bothAe.aegypti andAe.albopict...
Source: PLoS Neglected Tropical Diseases - April 10, 2024 Category: Tropical Medicine Authors: Janna R. Willoughby Source Type: research
Acute Kidney Injury after Catheter Ablation of Atrial Fibrillation: Comparison between Different Energy Sources
Pulsed field ablation (PFA) is an innovative technology recently adopted for treating atrial fibrillation (AF). Preclinical and clinical studies have reported a reassuring safety profile because of its tissue-specific effect, sparing adjacent tissues.1 However, two cases of acute kidney injury (AKI) secondary to hemolysis after PFA have recently been reported after an uncommonly high number of applications.2,3 Similarly, a subsequent pilot study reported the occurrence of AKI in 4/28 patients after PFA for AF. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Fabian Jordan, Sven Knecht, Corinne Isenegger, Rebecca Arnet, Philipp Krisai, Gian V öllmin, Jeanne du Fay de Lavallaz, David Spreen, Stefan Osswald, Christian Sticherling, Michael Kühne, Patrick Badertscher Source Type: research
Cancers, Vol. 16, Pages 1456: A Phase Ib Expansion Cohort Evaluating Aurora A Kinase Inhibitor Alisertib and Dual TORC1/2 Inhibitor Sapanisertib in Patients with Advanced Solid Tumors
Conclusions: Dual targeting of Aurora A kinase and mTOR resulted in marginal clinical benefit in a population of patients with refractory solid tumors, including pancreatic adenocarcinoma, though individual patients experienced significant response to therapy. Correlatives indicate apoptotic response and tumor immune cell infiltrate may affect clinical outcomes. (Source: Cancers)
Source: Cancers - April 10, 2024 Category: Cancer & Oncology Authors: S. Lindsey Davis Wells A. Messersmith W. Thomas Purcell Elaine T. Lam Bradley R. Corr Alexis D. Leal Christopher H. Lieu Cindy L. O ’Bryant Stephen G. Smoots Evan D. Dus Kimberly R. Jordan Natalie J. Serkova Todd M. Pitts Jennifer R. Diamond Tags: Article Source Type: research
Translation and validation of Vietnamese version of the Birth Satisfaction Scale-Revised (BSS-R)
CONCLUSION: The translated and validated VN-BSS-R is a psychometrically robust tool for measuring birth satisfaction in Vietnamese postpartum women.The VN-BSS-R is available for use to measure experiences and perceptions of intrapartum care received by Vietnamese women.PMID:38591499 | DOI:10.1080/02646838.2024.2338176 (Source: Journal of Reproductive and Infant Psychology)
Source: Journal of Reproductive and Infant Psychology - April 9, 2024 Category: Psychiatry & Psychology Authors: Sonya MacVicar Aileen Jordan Hien Vu Hai Ngoc Tran Yvonne Greig Hang Thi Tuyet Nguyen Gail Norris Colin R Martin Caroline J Hollins Martin Source Type: research
Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers
CONCLUSIONS: These results pave the way for clinical investigation of GD2IL18CART in pediatric and adult patients with neuroblastoma and other GD2-positive cancers (EU CT 2022-501725-21-00).PMID:38593230 | DOI:10.1158/1078-0432.CCR-23-3157 (Source: Cell Research)
Source: Cell Research - April 9, 2024 Category: Cytology Authors: Lena Fischer-Riepe Sareetha Kailayangiri Katharina Zimmermann Rita Pfeifer Michael Aigner Bianca Altvater Sascha Kretschmann Simon V ölkl Jordan Hartley Celine Dreger Katja Petry Andreas Bosio Angelika von D öllen Wolfgang Hartmann Holger Lode Dennis G Source Type: research
Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers
CONCLUSIONS: These results pave the way for clinical investigation of GD2IL18CART in pediatric and adult patients with neuroblastoma and other GD2-positive cancers (EU CT 2022-501725-21-00).PMID:38593230 | DOI:10.1158/1078-0432.CCR-23-3157 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 9, 2024 Category: Cancer & Oncology Authors: Lena Fischer-Riepe Sareetha Kailayangiri Katharina Zimmermann Rita Pfeifer Michael Aigner Bianca Altvater Sascha Kretschmann Simon V ölkl Jordan Hartley Celine Dreger Katja Petry Andreas Bosio Angelika von D öllen Wolfgang Hartmann Holger Lode Dennis G Source Type: research
Targeting the PI3K/AKT signaling pathway in anticancer research: a recent update on inhibitor design and clinical trials (2020 –2023)
. (Source: Expert Opinion on Therapeutic Patents)
Source: Expert Opinion on Therapeutic Patents - April 9, 2024 Category: Drugs & Pharmacology Authors: Dima A. SabbahRima HajjoSanaa K. BardaweelHaizhen A. Zhonga Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordanb Laboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, Eshelman Sc Source Type: research
