Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers

CONCLUSIONS: These results pave the way for clinical investigation of GD2IL18CART in pediatric and adult patients with neuroblastoma and other GD2-positive cancers (EU CT 2022-501725-21-00).PMID:38593230 | DOI:10.1158/1078-0432.CCR-23-3157

Source: Clinical Cancer Research - April 9, 2024 Category: Cancer & Oncology Authors: Lena Fischer-Riepe Sareetha Kailayangiri Katharina Zimmermann Rita Pfeifer Michael Aigner Bianca Altvater Sascha Kretschmann Simon V ölkl Jordan Hartley Celine Dreger Katja Petry Andreas Bosio Angelika von D öllen Wolfgang Hartmann Holger Lode Dennis G Source Type: research