Zinc: Zapping Invaders
Although zinc may appear last on nutrition labels, it’s the second-most abundant trace element in our bodies, behind only iron. (Trace elements are molecules our bodies need in small amounts to stay healthy). Zinc is crucial for a well-functioning immune system, wound healing, physical growth, the senses of taste and smell, and the construction of proteins and DNA. It can also partner with oxygen to form zinc oxide, a compound that scatters ultraviolet light and can act as a protective barrier over inflamed skin. Many sunscreens, burn ointments, diaper creams, and other skin treatments contain zinc oxide. Zinc m...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 24, 2021 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Cellular Processes Source Type: blogs

ePLAR: Echocardiographic Pulmonary to Left Atrial Ratio
ePLAR is a simple echocardiographic estimation useful in differentiating pre-capillary from post capillary pulmonary hypertension [1]. ePLAR = TR Vmax/(Mitral E/e’) ePLAR: Echocardiographic pulmonary to left atrial ratio TR Vmax: Maximum velocity of tricuspid regurgitation jet by Doppler echocardiography in m/s E: E wave in the mitral flow Doppler e’: Septal mitral annular tissue Doppler velocity ePLAR values are lower in post-capillary pulmonary hypertension. E/e’ reflects left ventricular filling pressure which is left atrial pressure. TR Vmax reflects the pulmonary artery systolic pressure. That is h...
Source: Cardiophile MD - February 22, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Echocardiography Source Type: blogs

Sunday Sermonette: Well okay then
I think Deuteronomy 28 is the longest chapter in the Torah, though I haven ' t tried to confirm that. Anyway, it ' s actually an expanded version of Leviticus 26, which recites the blessings the people will receive if they obey Yahweh and the evil that will befall them if they don ' t. It even uses some of the same language; the blessing section is quite similar, but it adds a lot to the curse part. I actually do recommend that you read this, for the black comedy value. Update: After I posted this, by coincidence I learned that Flavius Josephus, in his account of the rebellion against Roman rule that culminated in the...
Source: Stayin' Alive - February 21, 2021 Category: American Health Source Type: blogs

Wednesday Bible Study: A strange assortment
Deuteronomy 27 is something of a head scratcher. It strongly emphasizes a set of rules, two of which overlap with the Big Ten, the rest of which are a weird potpourri. Deuteronomy often has this feeling of having been thrown together more or less at random.27 Now Moses and the elders of Israel commanded the people, saying, “Keep all the commandment which I command you this day.2 And on the day you pass over the Jordan to the land which theLord your God gives you, you shall set up large stones, and plaster them with plaster;3 and you shall write upon them all the words of this law, when you pass over to ent...
Source: Stayin' Alive - February 17, 2021 Category: American Health Source Type: blogs

Sarah ’ s Wheat Belly health and life transformation
  Sarah’s story reminds us how the simple matter of diet can shape our lives for decades, affecting energy, body weight, emotional health–just about every aspect of our physical and social lives before we finally stumble on the right answers. After many years of struggling with poor health, relying on prescription medications that never addressed underlying causes, it therefore came as a surprise to Sarah that she could indeed achieve magnificent health without the drugs by simply following the diet programmed into human genetic code and supplementing nutrients that are deficient in modern life.   ...
Source: Wheat Belly Blog - January 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free Inflammation joint pain wheat belly Source Type: blogs

New dietary guidelines: Any changes for infants, children, and teens?
The United States Department of Agriculture (USDA) has published new dietary guidelines to help Americans get and stay healthier across all parts of the lifespan. Babies and toddlers are included for the first time, because the recommendations cover our full lifespan. The guidelines are called “Make Every Bite Count.” If we want to get and stay healthy, we shouldn’t be eating foods that are basically empty calories — or worse, foods that actually do us harm. Because foods can do us harm. Eating an unhealthy diet can lead to obesity, with the cardiovascular disease, diabetes, high blood pressure, and everything else...
Source: Harvard Health Blog - January 26, 2021 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Children's Health Healthy Eating Parenting Source Type: blogs

Fight Aging! Newsletter, January 25th 2021
In conclusion, our studies highlight the important role of the tyrosine degradation pathway and position TAT as a link between neuromediator production, dysfunctional mitochondria, and aging. (Source: Fight Aging!)
Source: Fight Aging! - January 24, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Inauguration Day Feels Like Groundhog Day for Buy American
Daniel J. IkensonExactly four years ago today, responding to the protectionist pledges in President Trump ' s inaugural speech, I warned of thefalse promise of Buy Americanregulations. Because ofthis memo from incoming White House Chief of Staff Ron Klain to incoming White House staff, I republish parts of that warning below. The memo notes that, by February 1, President Biden will take action to " fulfill his promises to strengthen Buy American provisions so the future of America is made in America, " which is another way of saying U.S. taxpayers will be charged double for half the infrastructure they ' re forced to buy, ...
Source: Cato-at-liberty - January 20, 2021 Category: American Health Authors: Daniel J. Ikenson Source Type: blogs

Iron Deposition in the Aging Brain Correlates with Glymphatic System Function
In this study, we recruited 213 healthy participants. We evaluated the function of the glymphatic system using the index for diffusivity along the perivascular space (ALPS-index), assessed iron deposition on quantitative susceptibility mapping (QSM), and analyzed their relationship. The main finding of the current study is that the regional brain iron deposition was related to the function of the glymphatic system. Previously, the glymphatic system has been speculated to be responsible for the clearance and homeostasis of waste in the brain. Our results support that in a healthy aging brain, the glymphatic system mi...
Source: Fight Aging! - January 18, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, January 18th 2021
In this study, Desferal, deferoxamine mesylate for injection, which is approved for the treatment of acute iron intoxication and chronic iron overload, was used to explore the beneficial effects on preventing aging-induced bone loss and mitigating dysfunction of aged BMSCs. High-dose Desferal significantly prevented bone loss in aged rats. Compared with controls, the ex vivo experiments showed that short-term Desferal administration could promote the potential of BMSC growth and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs and revise the expression of stemness/se...
Source: Fight Aging! - January 17, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Hypoxia Mimetic Drug Improves the Bone Marrow Environment to Treat Osteoporosis
In this study, Desferal, deferoxamine mesylate for injection, which is approved for the treatment of acute iron intoxication and chronic iron overload, was used to explore the beneficial effects on preventing aging-induced bone loss and mitigating dysfunction of aged BMSCs. High-dose Desferal significantly prevented bone loss in aged rats. Compared with controls, the ex vivo experiments showed that short-term Desferal administration could promote the potential of BMSC growth and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs and revise the expression of stemness/se...
Source: Fight Aging! - January 15, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Magnetic Nanoparticles Deliver Chem and Heat Cancer Cells for Synergistic Effects
Researchers at University College London have shown that tiny magnetic nanoparticles could enhance cancer treatment. The particles can deliver chemotherapy drugs to cancer cells and also produce a mild heating effect when stimulated with an external alternating magnetic field. Combining particle-mediated heat treatment and chemotherapy resulted in synergistic effects in killing cancer cells, suggesting that the technology could be a useful tool in the fight against cancer. Nanoparticles offer enormous potential in creating targeted and highly effective anti-cancer treatments. This latest technology combines two differen...
Source: Medgadget - January 7, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Materials Nanomedicine Oncology Source Type: blogs

Strengthen Your Immune System! Your Guide to The Ultimate 2021 New Year ’s Resolution
  Optimizing your immune system has perhaps never felt as critical as it does going into 2021. In 2020, we saw the emergence of the novel pathogen SARS-CoV-2, and the spread of its resulting disease, COVID-19. While this virus is novel, your immune system is anything but. In fact, your immune system has evolved over millions of years into an extremely complex and intricate network of cells and molecules that keep you alive on a daily basis. And, fortunately, there are steps you can take to help it function to the best of its ability. Immune System Basics All immunity can be broken down into two categories: innate and...
Source: GIDEON blog - January 5, 2021 Category: Databases & Libraries Authors: Kristina Symes Tags: News Tips Source Type: blogs

The Great Bucatini Shortage of 2020 and the FDA ’s History of Telling Italians How to Make Italian Food
Michael F. CannonRachel Handler has a  delightfulpiece atNew Yorkmagazine ’s food and restaurant blogGrub Street on how Big Pasta is using government regulation to punish competitors and consumers. The result is that the U.S. Food and Drug Administration, in addition to causing a  shortage of COVID-19diagnostic tests andvaccines, is basically causing a  nationwide shortage of bucatini.On March 30, at the beginning of a  pandemic whose supply shocks were making everything from toilet paper to pasta harder to get, the FDAblocked imports of De Cecco bucatini. The FDA found the iron content of the Italian company’s bu...
Source: Cato-at-liberty - December 30, 2020 Category: American Health Authors: Michael F. Cannon Source Type: blogs

Small Wonder Providers Don ’ t Like Sharing Patient Data For Free. It ’ s Becoming Their Whole Business.
During the decade or so in which I’ve been following data interoperability, the cleverest people in the healthcare and technology industries have come together to make disparate systems work together effectively. While there are still a number of technical issues to iron out, I’d go so far as to say that sustained data interoperability is […] (Source: EMR and HIPAA)
Source: EMR and HIPAA - December 28, 2020 Category: Information Technology Authors: Anne Zieger Tags: AI/Machine Learning Ambulatory Analytics/Big Data EMR-EHR Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring ACOs COVID-19 Pandemic Health Data Assets Health Data Sharing Health Data Value Health Information Source Type: blogs