The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
Isolation and genetic characterization of multiple genotypes of both H5 and H7 avian influenza viruses from environmental water in the Izumi plain, Kagoshima prefecture, Japan during the 2021/22 winter season
This study underscores the importance of monitoring both HPAIVs and LPAIVs to understand avian influenza virus ecology in migratory waterfowl populations.PMID:38640701 | DOI:10.1016/j.cimid.2024.102182 (Source: Comparative immunology, microbiology and infectious diseases.)
Source: Comparative immunology, microbiology and infectious diseases. - April 19, 2024 Category: Allergy & Immunology Authors: Kosuke Okuya Mana Esaki Kaori Tokorozaki Taichi Hasegawa Makoto Ozawa Source Type: research
Infection and transmission of henipavirus in animals
Comp Immunol Microbiol Infect Dis. 2024 Apr 17;109:102183. doi: 10.1016/j.cimid.2024.102183. Online ahead of print.ABSTRACTHenipavirus (HNV) is well known for two zoonotic viruses in the genus, Hendra virus (HeV) and Nipah virus (NiV), which pose serious threat to human and animal health. In August 2022, a third zoonotic virus in the genus Henipavirus, Langya virus (LayV), was discovered in China. The emergence of HeV, NiV, and LayV highlights the persistent threat of HNV to human and animal health. In addition to the above three HNVs, new species within this genus are still being discovered. Although they have not yet cau...
Source: Comparative immunology, microbiology and infectious diseases. - April 19, 2024 Category: Allergy & Immunology Authors: Xinyu Qiu Feng Wang Ailong Sha Source Type: research
Leptospira-specific immunoglobulin Y (IgY) is protective in infected hamsters
In conclusion, passive immunotherapy with specific IgY can be considered an effective treatment for leptospirosis, and may replace antibiotics regarding its therapeutic effects.PMID:38641497 | DOI:10.1016/j.vaccine.2024.04.010 (Source: Vaccine)
Source: Vaccine - April 19, 2024 Category: Allergy & Immunology Authors: Tianbao Lv Xufeng Xie Luteng Diao Shuang Jiang Yue Ding Xin Yuan Lingling Gong Xi Chen Wenlong Zhang Yongguo Cao Source Type: research
