TWiV 1100: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles influenza and SARS-CoV-2, before discussing the development of new monoclonal antibody therapy, if vaccines and antivial drugs can used effectively together. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound including that after administration of the “oral remdesivir”, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare w...
Source: This Week in Virology - MP3 Edition - March 30, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

SCCM Pod-504 CCM: Baricitinib or Tocilizumab for Severe COVID-19
Host Marilyn N. Bulloch, PharmD, BCPS, FCCM, is joined by Joy Peterson, PharmD, BCPS, BCIDP, Neha Paranjape, MD, MPH, to discuss the article, "Outcomes and Adverse Effects of Baricitinib Versus Tocilizumab in the Management of Severe COVID-19," (Crit Care Med. March 2023 51(3):337-346) which delves into the comparative outcomes, mortality rates, and adverse effects of baricitinib and tocilizumab in severe COVID-19 cases. Dr. Peterson is a Clinical Pharmacy Specialist in infectious disease, and Dr. Paranjape is an Infectious Disease Specialist at Wellstar Health System in Marietta, Georgia. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - March 25, 2024 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 1098: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin deep dives into recent domestic and global measles and mpox outbreaks, before reviewing recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2, discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how much oxygen is necessary for effective tr...
Source: This Week in Virology - MP3 Edition - March 23, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1086: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market and why people conceal their infectious diseases before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if susceptibility and disease severity are inheritable traits, if vaccination during pregnancy protects neonates or leads to adverse effects, the effectiveness of a monovalent XBB.1.5 against disease resulting from infection with Omicron variants, whether vaccination in the same or o...
Source: This Week in Virology - MP3 Edition - February 10, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

What are the benefits and risks of using topical insect repellents to prevent malaria?
Malaria is arguably the most important parasitic disease in the world and the Cochrane Infectious Diseases Group has produced more than 60 relevant reviews. These were added to in August 2023 with a new review of the effects of topical repellents. We asked lead author, Juan Carlos Gabaldon from the Barcelona Institute for Global Health in Spain to tell us about the findings in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - January 8, 2024 Category: General Medicine Authors: Cochrane Source Type: podcasts

TWiV 1076: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin highlights global circulation of Mpox virus, reviews the most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, and discusses the clinical outcome of hospitalized children under 5 years infected with SARS-CoV-2, the perinatal and neonatal outcomes including adverse effects of SARS-CoV-2 infection and virus transmission in Italy between early 2020 and 2022, the guidelines to improve home ventilation, the safety and efficacy of the oral anti-viral molnupiravir and the use of convalescent plasma as a long term treatme...
Source: This Week in Virology - MP3 Edition - January 6, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Oral killed cholera vaccines for preventing cholera
The Cochrane Infectious Diseases Group produces reviews that cover the prevention and treatment of a wide range of illnesses. These include cholera and their review on cholera vaccines was updated in January 2024. Here ' s the new lead author, KM Saif-Ur-Rahman from Evidence Synthesis Ireland and Cochrane Ireland in University of Galway to tell us more. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - December 7, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

TWiV 1063: Childhood paralysis with Kevin Messacar
Kevin Messacar visits the Incubator to discuss his career as a pediatric infectious disease physician, and his work on enteroviruses that are associated with acute flaccid myelitis and other diseases. Host: Vincent Racaniello Guest: Kevin Messacar Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Emergence of EV-D68 (Microbio Spectr) 2014 outbreak of EV-D68 (J Med Virol) EV-D68 shedding in households (...
Source: This Week in Virology - MP3 Edition - November 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Nasal Iodophor vs Nasal Mupirocin With Chlorhexidine Baths to Prevent Infections in Adult ICUs
Nasal mupirocin plus chlorhexidine baths in ICUs prevents methicillin-resistant Staphylococcus aureus (MRSA) infections but raises concern about antibiotic resistance. JAMA Senior Editor Kristin Walter, MD, speaks with Susan Huang, MD, of University of California, Irvine, about a study comparing iodophor vs mupirocin with chlorhexidine bathing for ICU-attributable S aureus clinical cultures. Related Content: Nasal Iodophor Antiseptic vs Nasal Mupirocin Antibiotic in the Setting of Chlorhexidine Bathing to Prevent Infections in Adult ICUs (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - October 10, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

How long can ancient DNA survive, and how much stuff do we need to escape poverty?
Pushing ancient DNA past the Pleistocene, and linking agriculture to biodiversity and infectious disease   First up on this week’s show, Staff Writer Erik Stokstad brings a host of fascinating stories, from the arrival of deadly avian flu in the Galápagos to measuring the effect of earthworms on our daily bread. He and host Sarah Crespi start off the segment discussing just how much stuff you need to avoid abject poverty and why measuring this value can help us balance human needs against planetary sustainability.   Other stories from Erik mentioned in this segment:   Elephant trunk’s ‘stunning’ microsc...
Source: Science Magazine Podcast - October 5, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

SCCM Pod-487: The Intersection of Climate Change and Critical Care
According to the United Nations, climate change is the defining crisis of our time and is happening more quickly than anticipated. Can critical care professionals be the spark that lights the fire of change? Kyle B. Enfield, MD, FSHEA, FCCM, was joined by Srinivas Murthy, MD, MDCM, MHSc, at the 2023 Critical Care Congress to discuss the intersection of climate change and critical care. Dr. Murthy is a pediatric infectious diseases and intensive care physician at the University of British Columbia in Vancouver British Columbia, Canada. His academic and clinical interests are in emerging and severe infections, innovative cli...
Source: SCCM PodCast - iCritical Care - August 16, 2023 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 1035: Poxvirus wars, warp speed COVID-19 vaccine rollout
TWiV dissects a study of COVID-19 vaccination which shows that the timing of initial rollout affects disease outcomes more substantially than final coverage or degree of socioeconomic disparity, and discovery of a novel cellular defense comprising a nuclease that is activated by poxvirus infection and cleaves a specific tRNA molecule to inhibit protein synthesis. Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant ...
Source: This Week in Virology - MP3 Edition - August 13, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1020: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses guidance on measles during the summer travel season, the Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: antigen testing, SARS-CoV-2 variants and age-dependent infection rates among household and nonhousehold contacts, effect of COVID-19 vaccination on household transmission of SARS-COV-2 in the Omicron era, incidence of myopericarditis after mRNA COVID-19 vaccination, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong, safety, immunogenicity and protection of heterol...
Source: This Week in Virology - MP3 Edition - July 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1015: Soldiers & Scientists at USAMRIID
Vincent and Rich travel to Ft. Detrick to visit USAMRIID and speak with Todd, Crystal, John and Jay about their careers, their research, and the mission of the US Army Medical Institute of Infectious Diseases. Host: Vincent Racaniello and Rich Condit Guests: Todd Bell, Crystal Burke, John Dye, and Jay Hooper Opinions, interpretations, conclusions, and recommendations are those of the panelists and no official endorsement by the U.S. Army should be inferred. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server USAMRIID Mpox virus in tes...
Source: This Week in Virology - MP3 Edition - June 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1003: Going clinically viral
Vincent and Kathy travel to Atlanta for APHL ID Lab Con, a conference focused on the latest developments in detecti​​on and characterization of infectious diseases of public health concern, and speak with Megan, Ryan, and Kirsten about the workings of public health and clinical laboratories. Hosts: Vincent Racaniello and Kathy Spindler Guests: Megan Crumpler, Ryan Relich, and Kirsten St. George Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server APHL Lab ID CON Association of Public Health Laboratories Orange County Public He...
Source: This Week in Virology - MP3 Edition - April 30, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts