Towards an actionable One Health approach
ConclusionsBy promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 12, 2024 Category: Infectious Diseases Source Type: research
Long-term variations of urban –Rural disparities in infectious disease burden of over 8.44 million children, adolescents, and youth in China from 2013 to 2021: An observational study
The objective of our study was to evaluate the long-term urban –rural disparities in infectious diseases among children, adolescents, and youths in China, while also examining the specific diseases driving these disparities. Methods and findingsThis observational study examined data on 43 notifiable infectious diseases from 8,442,956 cases from individuals aged 4 to 24 years, with 4,487,043 cases in urban areas and 3,955,913 in rural areas. The data from 2013 to 2021 were obtained from China ’s Notifiable Infectious Disease Surveillance System. The 43 infectious diseases were categorized into 7 categories: vaccine-prev...
Source: PLoS Medicine - April 12, 2024 Category: Internal Medicine Authors: Li Chen Source Type: research
Expectations of preventative benefits and risk behaviors in a randomized trial evaluating oral HIV preexposure prophylaxis candidates
. (Source: AIDS Care)
Source: AIDS Care - April 12, 2024 Category: Infectious Diseases Authors: Jeremy SugarmanBrian W. WeirChen DunRoy M. GulickTimothy J. WilkinKenneth H. MayerMarybeth McCauleyKevin P. Weinfurta Berman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USAb Department of Health, Behavior and Society, Johns Hopkins Bl Source Type: research
Intravenous immunoglobulin therapy for COVID-19 in immunocompromised patients: a retrospective cohort study
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a major public health concern since the start of the 2019 pandemic. Although current vaccines protect the general public, individuals with severe immunodeficiencies often exhibit a poor vaccine response and a higher risk of severe and/or persistent disease [1,2]. There are no treatment recommendations for persistent infection in immunocompromised individuals. Attempts with repeated antiviral mono or combination therapy has been described [3]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 12, 2024 Category: Infectious Diseases Authors: Remigius Gr öning, Jonatan Walde, Clas Ahlm, Mattias NE Forsell, Johan Normark, Johan Rasmuson Tags: Short Communication Source Type: research
Predictors of quality of life of TB/HIV co-infected patients in the Northern region of Ghana
Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) co-morbidity continues to be a serious worldwide health issue, particularly in Sub-Saharan Africa. Studies on th... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 12, 2024 Category: Infectious Diseases Authors: Jacob Nignan Nabei, Harriet Affran Bonful, Edwin Andrews Afari, Abdul Gafaru Mohammed and Adote Anum Tags: Research Source Type: research
Significance of early diagnosis and surgical management in treating Mycobacterium immunogenum-related pyogenic extensor tenosynovitis: a case report
Non-tuberculous mycobacteria (NTM) are environmental organisms that are increasingly contributing to human infections. Mycobacterium immunogenum, a variant of NTM discovered in 2001, is a rapidly growing mycobact... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 12, 2024 Category: Infectious Diseases Authors: Tomohide Okinaka, Kenjiro Fujimura, Yuka Hamasaki, Yuichi Hasegawa and Takashi Matono Tags: Case Report Source Type: research
Treatment of highly virulent mammarenavirus infections —status quo and future directions
. (Source: Expert Opinion on Drug Discovery)
Source: Expert Opinion on Drug Discovery - April 12, 2024 Category: Drugs & Pharmacology Authors: Ivette A. Nu ñezAnya CraneIan CrozierGabriella WorwaJens H. Kuhna Integrated Research Facility at Fort Detrick, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, USAb Clini Source Type: research
Molecules, Vol. 29, Pages 1754: Heavy Metal Removal from Aqueous Solutions Using a Customized Bipolar Membrane Electrodialysis Process
In conclusion, this process efficiently separates HMs from aqueous solutions. It showed the features of diluate pH adjustment, reduction in the overall stack electrical resistance, and contribution of anion exchange membranes in multivalent cation removal. The mechanisms involved in HMs removal were diffusion and migration from the bulk solution, followed by their sorption on both cation and anion exchange membranes. (Source: Molecules)
Source: Molecules - April 12, 2024 Category: Chemistry Authors: Samuel Bunani Gudrun Abbt-Braun Harald Horn Tags: Article Source Type: research
Pseudomonas fluorescens CRBSI outbreak: complying with the standardization of invasive procedures is a step ahead in the fight against antimicrobial resistance
AbstractIn the healthcare sector, the implementation of standardized procedures, such as those commonly employed in franchises to ensure consistent quality, remains underprioritized. Within this framework, we focus on the importance of standardized central venous catheter (CVC) insertion procedures to prevent healthcare-associated outbreaks. While antimicrobial resistance (AMR) may still not be the most prevalent problem in some institutions, its increasing significance certainly underlines the urgency of infection prevention.We aim to highlight this issue by describing and discussing an outbreak scenario of carbapenem-res...
Source: Antimicrobial Resistance and Infection Control - April 12, 2024 Category: Infectious Diseases Source Type: research
News at a glance: Jailed conservationists freed, physics titan dies, and diversity in anatomical illustrations
ASTRONOMY
Scientists flock to the eclipse
Tens of millions in North America turned their specially protected eyes to the skies on 8 April for several minutes of darkness when the Moon blocked the disk of the Sun, casting a shadow across Mexico, 15 U.S. states, and Canada. Researchers and citizen scientists seized the opportunity to study the corona—the wispy, outer layer of the Sun’s atmosphere—from the ground and in eclipse-chasing aircraft. They expected to see loops of plasma and other solar flares because the eclipse coincided with solar maximum, a period of high magnetic activity. Research...
Source: Science of Aging Knowledge Environment - April 11, 2024 Category: Geriatrics Source Type: research
Haemophilus aphrophilus and Eikenella corrodens Coinfection of Brain: An Unusual Case from China
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - April 11, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Hybrid Sequencing-Based Genomic Analysis of Klebsiella pneumoniae from Urinary Tract Infections Among Inpatients at a Tertiary Hospital in Beijing
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - April 11, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Understanding effective post-test linkage strategies for HIV prevention and care: a scoping review
CONCLUSIONS: The findings give insights into linkage strategies but more understanding of how to provide these effectively for maximum prevention impact is needed.PMID:38604993 | PMC:PMC11009370 | DOI:10.1002/jia2.26229 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 11, 2024 Category: Infectious Diseases Authors: Beatrice Wamuti Muhammad S Jamil Nandi Siegfried Nathan Ford Rachel Baggaley Cheryl Case Johnson Peter Cherutich Source Type: research
Discovery of novel Thymol-TPP antibiotics that eradicate MRSA persisters
Eur J Med Chem. 2024 Apr 3;270:116381. doi: 10.1016/j.ejmech.2024.116381. Online ahead of print.ABSTRACTThe high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) strains and the formation of non-growing, dormant "persisters" subsets help bacteria evade antibiotic treatment and enhance bacterial resistance, which poses a serious threat to human life and health. It is urgent to discover novel antibacterial therapies effective against MRSA persisters. Thymol is a common nutraceutical with weak antibacterial and antitumor activities. A series of Thymol triphenylphosphine (TPP) conjugates (TPP-Thy3) was designed...
Source: European Journal of Medicinal Chemistry - April 11, 2024 Category: Chemistry Authors: Ziyi Tang Jizhou Feng Mahesh Challa Sankara Rao Rowthu Shuxin Xiong Cheng Zou Jianguo Li Chandra Shekhar Verma Haibo Peng Xiaoli He Chao Huang Yun He Source Type: research
