First Report of OXA-181-Producing Klebsiella pneumoniae in China
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - April 6, 2020 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Targeting novel genes for simultaneous detection of five fungal and bacterial agents from BAL samples using multiplex PCR assay
AbstractThe main purpose of our study was to evaluate multiplex PCR assay targeting novel genes for detection of five fungal and bacterial agents in BAL samples; because many fungi and bacteria that cause respiratory infections have similar clinical symptoms, diagnosing and differentiating them are therefore essential to controlling and treating them. A total of 100 BAL specimens from a mycobacterium and mycology laboratory were collected from patients suspected of having TB or other respiratory diseases. Novel DNA targets forAspergillus,Nocardia,Cryptococcus, andStreptomyces were found using modified comparative genomic a...
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 6, 2020 Category: Microbiology Source Type: research

IJERPH, Vol. 17, Pages 2490: Investigating the Strategies Adopted by Emergency Nurses to Address Uncertainty and Change in the Event of Emerging Infectious Diseases: A Grounded Theory Study
g Chien Emergency nurses frequently encounter uncertainty and changes during the management of emerging infectious diseases, which challenge their capability to perform their duties in a well-planned and systematic manner. To date, little is known about the coping strategies adopted by emergency nurses in addressing uncertainty and changes during an epidemic event. The present study explored emergency nurses’ behaviours and strategies in handling uncertainty and practice changes during an epidemic event. A qualitative study based on the Straussian grounded theory approach was established. Semi-structured, face-to...
Source: International Journal of Environmental Research and Public Health - April 6, 2020 Category: Environmental Health Authors: Stanley K.K. Lam Enid W.Y. Kwong Maria S.Y. Hung Wai-tong Chien Tags: Article Source Type: research

Risk of nosocomial transmission of coronavirus disease 2019: an experience in a general ward setting in Hong Kong
Publication date: Available online 4 April 2020Source: Journal of Hospital InfectionAuthor(s): S.C.-Y. Wong, R.T.-S. Kwong, T.C. Wu, J.W.M. Chan, M.Y. Chu, S.Y. Lee, H.Y. Wong, D.C. Lung (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - April 5, 2020 Category: Infectious Diseases Source Type: research

Indwelling medical device use and sepsis risk at a health professional shortage area hospital: Possible interaction with length of hospitalization
Publication date: Available online 5 April 2020Source: American Journal of Infection ControlAuthor(s): Peter D. Ahiawodzi, Ikenna Okafor, Sarah Chandler, Kimberly Kelly, Dorothea K. Thompson (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - April 5, 2020 Category: Infectious Diseases Source Type: research

A Public Health Systems View of Risk Communication About Zika.
CONCLUSIONS: Lessons learned from this disease response included understanding the macro-environment, developing partnerships across agencies and the community, and valuing diverse message platforms. These lessons can be used to improve communication approaches for health officials at the local, state, and federal levels during future infectious disease outbreaks. PMID: 32243762 [PubMed - as supplied by publisher] (Source: Public Health Reports)
Source: Public Health Reports - April 5, 2020 Category: International Medicine & Public Health Tags: Public Health Rep Source Type: research

Alternative approaches to treat bacterial infections: targeting quorum-sensing.
We present the components of QS systems that form possible targets for the development of anti-virulence drugs and discuss recent research on quorum-quenching approaches to control bacterial infection.Expert opinion: While there has been extensive research on QS systems and quorum-quenching approaches, there is a paucity of in-vivo research using adequate animal models to substantiate applicability. In-vivo research on QS blockers needs to be intensified and optimized to use clinically relevant setups, in order to underscore that such drugs can be used effectively to overcome problems associated with the treatment of sever...
Source: Expert Review of Anti-Infective Therapy - April 5, 2020 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Natural and vaccine-induced B cell-derived systemic and mucosal humoral immunity to human papillomavirus.
Authors: Mboumba Bouassa RS, Péré H, Jenabian MA, Veyer D, Meye JF, Touzé A, Bélec L Abstract Introduction: Human papillomavirus (HPV) play an important role in the pathogenesis of mucosal neoplasia. Considering that cervical cancer is the fourth common cancer in women worldwide and that the global incidence of both HPV-associated anal and oropharyngeal cancers is constantly increasing, especially in men, infection with HPV can be regarded as a worldwide concern. HPV-specific adaptive immune response which involve CD8+ cytotoxic T cells as well as humoral responses both coordinated by CD...
Source: Expert Review of Anti-Infective Therapy - April 5, 2020 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Innovative therapies for acute bacterial skin and skin-structure infections (ABSSSI) caused by methicillin-resistant Staphylococcus aureus: advances in phase I and II trials.
Authors: Bassetti M, Del Puente F, Magnasco L, Giacobbe DR Abstract Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is among the most frequent causative agents of acute bacterial skin and skin-structure infections (ABSSSI) and has been associated with increased risks of invasive disease and of treatment failure.Areas covered: In this review, we focus on those novel anti-MRSA agents currently in phase I or II of clinical development that may enrich the armamentarium against ABSSSI caused by MRSA in the future.Expert opinion: Promising agents belonging to either old or novel antibiotic classes are cu...
Source: Expert Opinion on Investigational Drugs - April 5, 2020 Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research

Severe extrarenal manifestations of nephropathia epidemica induced by Puumala hantavirus in two family cases.
Authors: Duez L, Ho TA, Ledent T, Holovska V, Papaleo A, Milas S PMID: 32241647 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 5, 2020 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

C-reactive protein levels in the early stage of COVID-19.
CONCLUSION: In the early stage of COVID-19 CRP levels were positively correlated with lung lesions and could reflect disease severity. PMID: 32243911 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 5, 2020 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

COVID-19 contagion and contamination through hands of trauma patients: what risks and what precautions?
Publication date: Available online 4 April 2020Source: Journal of Hospital InfectionAuthor(s): Rocco De Vitis, Marco Passiatore, Andrea Perna, Luca Proietti, Giuseppe Taccardo (Source: Journal of Hospital Infection)
Source: Journal of Hospital Infection - April 5, 2020 Category: Infectious Diseases Source Type: research

Co-occurrence of mcr-1 mediated colistin resistance and β-lactamases encoding genes in Multidrug-resistant Escherichia coli from broiler chickens with colibacillosis in Tunisia
Publication date: Available online 3 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Sana Dhaouadi, Leila Soufi, Amani Hamza, Didier Fedida, Chtioui Zied, Emna Awadhi, Mohamed Mtibaa, Bilel Hassen, Ameur Cherif, Carmen Torres, Mohamed Salah Abbassi, Ramzi Boubaker Landolsi (Source: Journal of Global Antimicrobial Resistance)
Source: Journal of Global Antimicrobial Resistance - April 5, 2020 Category: Infectious Diseases Source Type: research

High genetic diversity among methicillin-susceptible Staphylococcus pseudintermedius in dogs in Europe
Publication date: June 2020Source: Journal of Global Antimicrobial Resistance, Volume 21Author(s): Marisa Haenni, Farid El Garch, Christine Miossec, Jean-Yves Madec, Didier Hocquet, Benoit Valot (Source: Journal of Global Antimicrobial Resistance)
Source: Journal of Global Antimicrobial Resistance - April 5, 2020 Category: Infectious Diseases Source Type: research

Whole genome sequence analysis of multi-drug resistant Staphylococcus epidermidis(MRSE) ST35 strain isolated from human ear infection of an Iraqi patient
Publication date: Available online 3 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Absar Talat, Shamsi Khalid, Hayder Abdul R Majeed, Asad U. Khan (Source: Journal of Global Antimicrobial Resistance)
Source: Journal of Global Antimicrobial Resistance - April 5, 2020 Category: Infectious Diseases Source Type: research

Management of cerebral azole-resistant A. fumigatus infection. A role for intraventricular liposomal-amphotericin B?
Publication date: Available online 3 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): A.F.A.D. Schauwvlieghe, R.G.M. Bredius, Rob M. Verdijk, Frans J.W. Smiers, Martha T. van der Beek, Bianca F. Goemans, C. Michel Zwaan, Roger J. Brüggemann, Bart J.A. Rijnders (Source: Journal of Global Antimicrobial Resistance)
Source: Journal of Global Antimicrobial Resistance - April 5, 2020 Category: Infectious Diseases Source Type: research

Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline
Publication date: Available online 4 April 2020Source: IDCasesAuthor(s): Mariana Guedes, Raquel Duro, Telma Fonseca, Isabel Abreu, Nuno Rocha-Pereira (Source: IDCases)
Source: IDCases - April 5, 2020 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: June 2020Source: Comparative Immunology, Microbiology and Infectious Diseases, Volume 70Author(s): (Source: Comparative Immunology, Microbiology and Infectious Diseases)
Source: Comparative Immunology, Microbiology and Infectious Diseases - April 5, 2020 Category: Infectious Diseases Source Type: research

Scorpion venoms and associated toxins as anticancer agents: update on their application and mechanism of action
AbstractCancer remains one of the deadliest non ‐infectious diseases of the 21st century, causing millions of mortalities per year worldwide. Analyses of conventional treatments, such as radiotherapy and chemotherapy, have shown not only a lower therapeutic efficiency rate but also plethora of side ‐effects. Considering the desperate need to identify promising anticancer agents, researchers are in quest to design and develop new tumoricidal drugs from natural sources. Over the past few years, scorpion venoms have shown exemplary roles as pivotal anticancer agents. Scorpion venoms associated metabolites, particularly to...
Source: Journal of Applied Toxicology - April 5, 2020 Category: Toxicology Authors: Erasto Desales ‐Salazar, Ameer Khusro, Moisés Cipriano‐Salazar, Alberto Barbabosa‐Pliego, Raymundo Rene Rivas‐Caceres Tags: REVIEW ARTICLE Source Type: research

The role of close contacts tracking management in COVID-19 prevention: A cluster investigation in Jiaxing, China
Recently, there have been some studies of COVID-19 reported in this journal.1,2 The 2019 coronavirus outbreak has affected more than 60 countries. As of 6 March 2020, 100,326 patients have been reported, including 80,718 cases in China and 19,608 in other countries. The cause, a novel contagious respiratory virus named as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), also known as COVID-19, is a serious threat to global public health, like severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and middle east respiratory syndrome coronavirus (MERS-CoV) in 2015. (Source: Journal of Infection)
Source: Journal of Infection - April 5, 2020 Category: Infectious Diseases Authors: Rui Ge, Yunpeng Qi, Yong Yan, Min Tian, Qijun Gu, Peigen Chen, Yuegen Shen, Zhongwen Chen Tags: Letter to the Editor Source Type: research

Implementation of the WASPLab ™ and first year achievements within a university hospital
AbstractIn essence, automation can be driven by several of the following incentives: increased processing capacity of the laboratory, better costs control through processes standardization, optimized traceability, or improved workflows to reduce turnaround times (TAT). This project aims at presenting an overview of the project management and change management with a focus on the major challenges addressed by lab staff and laboratory leadership during the different phases of the implementation of the WASPLab ™ in a routine clinical bacteriology laboratory. This paper reports our experience and reviews changes in the b...
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 5, 2020 Category: Microbiology Source Type: research

Out-of-Hospital Cohort Treatment of Coronavirus Disease 2019 Patients with Mild Symptoms in Korea: an Experience from a Single Community Treatment Center.
Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) caused a worldwide pandemic. Less than 6 weeks after the first confirmed cases in Korea, the patient number exceeded 5,000, which overcrowded limited hospital resources and forced confirmed patients to stay at home. To allocate medical resources efficiently, Korea implemented a novel institution for the purpose of treating patients with cohort isolation out of hospital, namely the Community Treatment Center (CTC). Herein, we report results of the initial management of patients at one of the largest CTC in Korea. A total of 309 patients were admitted to o...
Source: J Korean Med Sci - April 4, 2020 Category: General Medicine Authors: Park PG, Kim CH, Heo Y, Kim TS, Park CW, Kim CH Tags: J Korean Med Sci Source Type: research

Environmental pollutants modulate RNA and DNA virus-activated miRNA-155 expression and innate immune system responses: Insights into new immunomodulative mechanisms.
In conclusion, this study added evidence that mir-155 signaling represents a sensitive pathway to chemically-induced immunomodulation and indicated that PCBs can modulate highly-regulated innate immune system signaling pathways important in determining host immune response outcomes during viral infections. PMID: 32233818 [PubMed - in process] (Source: Herpes)
Source: Herpes - April 4, 2020 Category: Infectious Diseases Authors: Badry A, Jaspers VLB, Waugh CA Tags: J Immunotoxicol Source Type: research

[Vascular Remodeling Induced by Biological Stresses].
Abstract The thymus is a vital organ for functional immune systems, and is the site of T cell development, which plays a central role in cellular immune defenses. Unlike other major organs, the thymus is highly dynamic in size and structure. It shrinks immediately upon bacterial infection, aging, pregnancy, mental stress, nutritional deficiency, and more. The reduction in size and function of the thymus during such biological events is called thymic involution or thymic atrophy; thymic involution is a particularly important issue because dysfunctional T cell immunity increases the risks of tumorigenesis and infect...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 4, 2020 Category: Drugs & Pharmacology Authors: Hasegawa H Tags: Yakugaku Zasshi Source Type: research

[Localization and Accumulation Studies of Daptomycin in Rats Kidney Using Immunohistochemistry].
This study will be a useful tool for analyzing the pharmacokinetics of DAP. PMID: 32238639 [PubMed - in process] (Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan)
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 4, 2020 Category: Drugs & Pharmacology Authors: Yamamoto Y, Yamamoto Y, Saita T, Shin M Tags: Yakugaku Zasshi Source Type: research

[Evaluation of the Usefulness of a Completely Separated Infection Waiting Room and Non-infection Waiting Room in a Pediatric Neighborhood Pharmacy].
In this study, we examined the potential usefulness of having separate waiting rooms by conducting a questionnaire survey on the structure of the pharmacy waiting room and investigating the visiting situation for influenza-infected pediatric patients from a record of the medicines they received. As a result of the questionnaire tabulated from guardians of 385 pediatric patients who first visited a pharmacy with separate waiting rooms, 70% of the pediatric patients concluded that having separate waiting rooms would be satisfactory. In addition, the possible risk of horizontal transmission of influenza was supposed to be red...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - April 4, 2020 Category: Drugs & Pharmacology Authors: Norikoshi Y, Uchiyama M, Ibusuki T, Nakashima N, Torigoe E, Ito E, Nagae M, Saruwatari J, Anraku M Tags: Yakugaku Zasshi Source Type: research

Authoritarianism and the threat of infectious diseases
Publication date: 4–10 April 2020Source: The Lancet, Volume 395, Issue 10230Author(s): Juan M Pericàs (Source: The Lancet)
Source: The Lancet - April 4, 2020 Category: General Medicine Source Type: research

Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea.
Authors: Hong KH, Lee SW, Kim TS, Huh HJ, Lee J, Kim SY, Park JS, Kim GJ, Sung H, Roh KH, Kim JS, Kim HS, Lee ST, Seong MW, Ryoo N, Lee H, Kwon KC, Yoo CK, Korean Society for Laboratory Medicine, COVID-19 Task Force and the Center for Laboratory Control of Infectious Diseases, the Korea Centers for Disease Control and Prevention Abstract The outbreak of coronavirus disease 2019 (COVID-19), which began in December 2019, is still ongoing in Korea, with>9,000 confirmed cases as of March 25, 2020. COVID-19 is a severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and real-time reverse transcriptio...
Source: Annals of Laboratory Medicine - April 4, 2020 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research

Children and their families are entitled to the benefits of differentiated ART delivery.
Authors: Wilkinson L, Siberry GK, Golin R, Phelps BR, Wolf HT, Modi S, Grimsrud A PMID: 32239657 [PubMed - as supplied by publisher] (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 4, 2020 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

Monotherapy with Vancomycin or Daptomycin versus Combination Therapy with β-Lactams in the Treatment of Methicillin-Resistant Staphylococcus Aureus Bloodstream Infections: A Retrospective Cohort Analysis
ConclusionsIn hospitalized adults with MRSA BSI, CT with any BL was independently associated with improved clinical outcomes and may ultimately be selected as preferred therapy. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 4, 2020 Category: Infectious Diseases Source Type: research

The other side of novel coronavirus outbreak: fear of performing cardiopulmonary resuscitation
When CPR is immediately performed before ambulance arrival, the chances of survival are three times higher.1 Nevertheless, laypeople are historically afraid they may contract an infectious disease while performing cardiopulmonary resuscitation (CPR). The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China at the end of 2019 has become a global public health concern. SARS-CoV-2 is generating panic across the globe due to the outbreak of the Coronavirus disease 2019 (COVID-19). (Source: Resuscitation)
Source: Resuscitation - April 4, 2020 Category: Emergency Medicine Authors: Tommaso Scquizzato, Theresa Mariero Olasveengen, Giuseppe Ristagno, Federico Semeraro Tags: Letter to the Editor Source Type: research

Adult-onset still & #39;s disease, an unusual cause of severe acute liver injury: A case report
SC Adiyaman, G Bengi, M Civak, M Birlik, Z Kuruuzum, C Altay, M SoyturkNigerian Journal of Clinical Practice 2020 23(4):581-585 Adult-onset Still's disease is a systemic inflammatory disease that often presents with spiking fever, typical rash, arthritis, and serositis. However, adult-onset-Still's-disease associated liver injury and acute liver failure are rare. Herein, we report a case of acute liver injury in a 23-year-old female patient with adult-onset Still's disease. She presented to the emergency department with a high fever and sore throat. She was then admitted to the department of infectious disease...
Source: Nigerian Journal of Clinical Practice - April 4, 2020 Category: Rural Health Authors: SC Adiyaman G Bengi M Civak M Birlik Z Kuruuzum C Altay M Soyturk Source Type: research

HIV Treatment Knowledge in the Context of “Treatment as Prevention” (TasP)
This study used descriptive analysis of quantitative d ata (N = 99) and thematic analysis of qualitative interviews (n = 36) to compare participants recruited from a hospital-based detoxification (detox) unit, largely diagnosed with HIV pre-2012 (n = 63) vs. those recruited from public, urban sexual health clinics (SHCs), mainly diagnosed in 2012 or later (n = 36). Detox participants were significantly more knowledgeable than SHC participants about HIV treatment, except regarding TasP. SHC participants’ desire for rapid linkage to care and ART initiation was in ...
Source: AIDS and Behavior - April 4, 2020 Category: Infectious Diseases Source Type: research

Drug Use Among Adolescents and Young Adults with Unsuppressed HIV Who Use Alcohol: Identifying Patterns of Comorbid Drug Use and Associations with Mental Health
AbstractYouth living with HIV (YLWH; aged 16 –24) are at elevated risk of alcohol and drug use. Studies in older populations have identified patterns or profiles of multiple substance use differentially associated with mental health and anti-retroviral therapy (ART) adherence. No studies of YLWH have yet examined such patterns. A sample of 1 79 YLWH, reporting ART non-adherence and alcohol use, were recruited at five Adolescent Trials Network clinics in urban areas of the US between November 2014 and August 2017. Participants completed the Alcohol Smoking and Substance Involvement Screening Test (ASSIST) to assess su...
Source: AIDS and Behavior - April 4, 2020 Category: Infectious Diseases Source Type: research

Preventing catheter-related infections in cancer patients: a review of current strategies.
Authors: Malek AE, Raad II Abstract Introduction: Central line-associated bloodstream infections (CLABSI) are a frequent cause of healthcare-associated infections, increasing healthcare costs and decreasing the quality of life for critically and chronic ill patients such as those with cancer. These infections are largely preventable and have been significantly reduced throughout the United States. However, further reduction of CLABSI requires continued innovation in preventive strategies.Areas covered: We provide an overview of the recent medical literature on catheter-related infections among cancer patients, disc...
Source: Expert Review of Anti-Infective Therapy - April 3, 2020 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Multidrug-resistant Candida auris: an epidemiological review.
Authors: Chakrabarti A, Singh S Abstract Introduction: Since the emergence of Candida auris infection in 2009, the disease has been reported from multiple countries within a decade. The infection is classified under urgent threat, as it is multi-drug resistant, causes high mortality, spreads easily in hospital setting and is difficult to identify. Whole-genome sequencing has provided insights into this organisms biology and epidemiology. A comprehensive review of those issues would help the clinicians and scientists facing C. auris infection.Areas covered: We reviewed the epidemiological trends of C. auris infectio...
Source: Expert Review of Anti-Infective Therapy - April 3, 2020 Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research

Effects of Infectious Bursal Disease Virus Infection on Interferon and Antiviral Gene Expression in Layer Chicken Bursa
Publication date: Available online 2 April 2020Source: Microbial PathogenesisAuthor(s): Yan Yu, Zhiyong Xu, Yan Liu, Huan Zhang, Changbo Ou, Yanhong Zhang, Tingyu Liu, Qiuxia Wang, Jinyou Ma (Source: Microbial Pathogenesis)
Source: Microbial Pathogenesis - April 3, 2020 Category: Infectious Diseases Source Type: research

Molecular subtyping and clonal relatedness of human and cattle verotoxin-producing Escherichia coli O157:H7 isolates
Publication date: Available online 3 April 2020Source: Microbial PathogenesisAuthor(s): González Juliana, Cadona Jimena, Sanso Mariel, Bustamante Ana (Source: Microbial Pathogenesis)
Source: Microbial Pathogenesis - April 3, 2020 Category: Infectious Diseases Source Type: research

Novel IS26-mediated hybrid plasmid harboring tet(X4) in Escherichia coli
Publication date: Available online 2 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Pengcheng Du, Dejun Liu, Huangwei Song, Pei Zhang, Ruichao Li, Yulin Fu, Xiao Liu, Jinli Jia, Xiaodi Li, Séamus Fanning, Yang Wang, Li Bai, Hui Zeng (Source: Journal of Global Antimicrobial Resistance)
Source: Journal of Global Antimicrobial Resistance - April 3, 2020 Category: Infectious Diseases Source Type: research

SARS-CoV-2 infection presenting with hematochezia.
Authors: Li G, Zhao X, Dong Z, Wang H PMID: 32229159 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 3, 2020 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

No Evidence of Rapid Antiviral Clearance or Clinical Benefit with the Combination of Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection.
Authors: Molina JM, Delaugerre C, Goff JL, Mela-Lima B, Ponscarme D, Goldwirt L, de Castro N PMID: 32240719 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - April 3, 2020 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research

Am J Trop Med Hyg; +24 new citations
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2020/04/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 3, 2020 Category: Infectious Diseases Tags: Report Source Type: research

GSE145974 Global transcriptome analysis identifies a signature for early disseminated Lyme disease and its resolution
We examined gene expression patterns in the blood of individuals with early disseminated LD at the time of diagnosis (Acute LD) and also at approximately 1 month and 6 months following antibiotic treatment. A distinct acute LD profile was observed that was sustained during early convalescence (1 month) but returned to control levels six months after treatment. Using a computer learning algorithm, we identified sets of 20 classifier genes that discriminate LD from other bacterial and viral infections. In addition, these novel LD biomarkers are highly acurate in distinvuishing patients with acute LD from healthy subjects and...
Source: GEO: Gene Expression Omnibus - April 3, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by array Source Type: research

Severe Acute Respiratory Syndrome Coronavirus 2 RNA Detected in Blood Donations
L. Chang et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - April 3, 2020 Category: Infectious Diseases Source Type: research

Daily fluctuating temperatures decrease growth and reproduction rate of a lethal amphibian fungal pathogen in culture
Emerging infectious diseases (EIDs) are contributing to species die-offs worldwide. We can better understand EIDs by using ecological approaches to study pathogen biology. For example, pathogens are exposed to... (Source: BMC Ecology)
Source: BMC Ecology - April 3, 2020 Category: Biology Authors: Alexa L. Lindauer, Paul A. Maier and Jamie Voyles Tags: Research article Source Type: research

Hepatitis E virus outbreak associated with rainfall in the Central African Republic in 2008-2009
Infection by hepatitis E virus (HEV) can cause a high burden of morbidity and mortality in countries with poor access to clean water and sanitation. Our study aimed to investigate the situation of HEV infectio... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 3, 2020 Category: Infectious Diseases Authors: Vianney Tricou, Julie Bouscaillou, Gina-Laure Laghoe-Nguembe, Aubin B éré, Xavier Konamna, Benjamin Sélékon, Emmanuel Nakouné, Mirdad Kazanji and Narcisse P. Komas Tags: Research article Source Type: research

Q fever seroprevalence in parturient women: the EQRUN cross-sectional study on Reunion Island
Q fever (Coxiella burnetii infection) has been associated with adverse perinatal outcomes. After investigating the obstetrical importance of Q fever on Reunion island and demonstrating an association between inci... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 3, 2020 Category: Infectious Diseases Authors: Julien Jaubert, Laura Atiana, Sophie Larrieu, Philippe De Vos, Claudine Somon-Payet, Sylvaine Porcherat, Yoan Mboussou, Florence Naze, Sandrine Picot, Malik Boukerrou, Pierre-Yves Robillard and Patrick G érardin Tags: Research article Source Type: research

Molecular characterization of human Echinococcus isolates and the first report of E. canadensis (G6/G7) and E. multilocularis from the Punjab Province of Pakistan using sequence analysis
Echinococcosis is a zoonotic parasitic disease causing serious health problems in both humans and animals in different endemic regions across the world. There are two different forms of human echinococcosis: C... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 3, 2020 Category: Infectious Diseases Authors: Aisha Khan, Haroon Ahmed, Sami Simsek, Hua Liu, Jianhai Yin, Ying Wang, Yujuan Shen and Jianping Cao Tags: Research article Source Type: research

Solidarity, vulnerability and mistrust: how context, information and government affect the lives of women in times of Zika
The public health response to Zika outbreak has mostly focused on epidemiological surveillance, vector control, and individual level preventative measures. This qualitative study employs a social-ecological fr... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 3, 2020 Category: Infectious Diseases Authors: Ana Rosa Linde-Arias, Maria Roura and Eduardo Siqueira Tags: Research article Source Type: research

Ombitasvir/paritaprevir/ritonavir & dasabuvir ± ribavirin following protease inhibitors failure - a prospective multi-centre trial
Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and hepatocellular carcinoma. Treatment with first generation protease inhibitors (PI)  + peg-interferon (pegIFN) and ribavirin (RBV... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 3, 2020 Category: Infectious Diseases Authors: Liat Deutsch, Inbal Houri, Ziv Ben-Ari, Amir Shlomai, Ella Veitsman, Oranit Cohen-Ezra, Assaf Issachar, Orna Mor, Yael Gozlan, Rafael Bruck, Yoram Menachem, Shira Zelber-Sagi, Helena Katchman and Oren Shibolet Tags: Research article Source Type: research