Evaluating the impact of automatic positive airway pressure therapy on cardiovascular risk index and vascular behavior in patients with obstructive sleep apnea: a study on heterogeneity in the therapeutic response
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - April 22, 2024 Category: Sleep Medicine Authors: Wenjun Zhu Lin Xiang Linna Cao Yaping Tian Wenjun Li Lirong He 1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, China 2Department of Respiratory and Sleep Medicine, Peking University P Source Type: research

Exploring sleep characteristics in Chinese patients with narcolepsy: insights from the nocturnal sleep onset rapid eye movement period (nSOREMP)
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - April 22, 2024 Category: Sleep Medicine Authors: Shufei Zeng Fei Feng Weimin Li Yan Xu Rui Zhao Shengpeng Liang Yihong Cheng Ruichen Fang Hailing Jia Yang Wang Dongsheng Lv Bin Zhang 1Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University 2Key Laboratory of Mental Source Type: research

Analysis and prevention strategies of risk factors for postoperative stroke complications in cardiac surgery
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 22, 2024 Category: Neuroscience Authors: Liang WeiJie LiFeng ZhengYan ZhangDepartment of Cardiac and Vascular Surgery, Affiliated Huai ’an Hospital of Yangzhou University, Huai’an, China Source Type: research

Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - April 22, 2024 Category: Toxicology Authors: Ben YuanJunbiao MaoJunling WangShuhong LuoBingbing Luoa Department of Reproductive Medicine, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi, Chinab Huangshi Key Laboratory of Assisted Reproduction and Reproductive Source Type: research

Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - April 22, 2024 Category: Toxicology Authors: Haihui LiuLiujiangshan JiangSi XuChen WangJingyi Suna Department of Environmental Health, School of Public Health, China Medical University, Shenyang, PR Chinab Department of Cardiology, The Second Hospital of Dalian Medical University, Dalian, PR China Source Type: research

PM2.5 associates with blood pressure: a Mendelian randomization analysis
. (Source: International Journal of Environmental Health Research)
Source: International Journal of Environmental Health Research - April 22, 2024 Category: Environmental Health Authors: Minghui BaoHaotong LiYan ZhangJianping Lia Department of Cardiology, Peking University First Hospital, Peking University, Beijing, Chinab National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Med Source Type: research

Measuring Equity in Readmission as an Assessment of Hospital Performance
To the Editor A recent study that used Medicare administrative data reported disparities in readmission rates for Black compared with White beneficiaries and notable segregation in the care of Black and White patients among hospitals. These findings necessitate attention to additional structural factors contributing to the observed disparities, extending beyond between-hospital –level segregation to the community and other health system levels. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Measuring Equity in Readmission as an Assessment of Hospital Performance —Reply
In Reply We agree with Drs Gallo and Santiago that research is needed to identify and target the upstream contributors to disparities in hospital readmissions. These root causes function both at the level of the hospital and outside of the hospital via the social determinants of health (SDoH). In our recent study, we proposed a novel measure of equity —an important domain of health care quality that has only recently been incorporated into formal hospital accountability programs. Quality measurement, through its use in public reporting and value-based payment programs, is a known and effective policy-level intervention t...
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Gastritis cystica profunda presenting as an ulcerated lesion
A 57-year-old man was referred to our hospital due to repeated upper abdominal discomfort for more than 1 year. Endoscopy was performed 4 times in the past and gastric cancer was suspected, but biopsy showed inflammation. In our hospital, endoscopy showed a 2.5 cm diameter depressed lesion on the gastric angle (Fig. 1A) and magnifying narrow band imaging observed the central surface structure of the lesion disappeared (Fig. 1B). Endoscopic ultrasound (EUS) revealed a 0.8 × 0.7 cm anechoic area in the submucosa (Fig. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 22, 2024 Category: Gastroenterology Authors: Yang Li, Ruide Liu, Ziqiang Wang, Yi Mou Tags: Image of the Month Source Type: research

Primary survey: highlights from this issue
‘Free vapes given to smokers at hospitals could help thousands quit, study suggests.’ And ‘Calls for free vapes to be handed out in emergency departments.’ These were the headlines describing this month’s Editor’s Choice, the Cessation of Smoking Trial in the Emergency Department (COSTED), when it was published on-line in March. Of course COSTED wasn’t just about vapes. This randomised, controlled study conducted by Pope and colleagues at 6 UK emergency departments (ED) recruited patients attending for any reason who smoked daily. Intervention patients received 15 min of face-to-fa...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Weber, E. J. Tags: Highlights from this issue Source Type: research

GP patients in the emergency department
In this edition of the Emergency Medicine Journal, Dr Cooper and her colleagues explore the facilitators and barriers to the effectiveness of different general practitioner service models in or alongside EDs (GP-ED).1 The availability of these services in the UK expanded in response to a 2017 budget commitment of £100 million to enhance A&E services including the colocation of on-site GP services.2 The authors observed that the demand for ED services is influenced by a range of individual, department and wider system factors, but that colocated GP/ED service models did not reduce attendances and waiting times and...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: FitzGerald, G. Tags: In perspective Source Type: research

Journal update monthly top five
This month’s update comes from the Emergency Department at Northern General Hospital, Sheffield. We used a multimodal search strategy, drawing on free open-access medical education resources and literature searches. We identified the five most interesting and relevant papers (decided by consensus) and highlight the main findings, key limitations and clinical bottom line for each paper. Worth a peek—interesting, but not yet ready for prime time. Head turner—new concepts. Game changer—this paper could/should change practice. A non-inferiority randomised controlled trial comparing nebulised ketamine to...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Trimble, A., Sampson, B., Underwood, C. G., Cherian, R., McDonald, F., Webster, V., Shepherd, J., van Oppen, J. D. Tags: Journal update Source Type: research

The addiction consultation service for hospitalized patients with substance use disorder: An integrative review of the evidence
The Addiction Consultation Service has emerged as a model of care for hospitalized patients with substance use disorder. The aim of this integrative review is to characterize the Addiction Consultation Service in general hospital settings, assess its impact on clinical outcomes, identify knowledge gaps, and offer guidance for implementation. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - April 22, 2024 Category: Addiction Authors: Itai Danovitch, Samuel Korouri, Harlene Kaur, Gabrielle Messineo, Teryl Nuckols, Waguih W. Ishak, Allison Ober Source Type: research

Molecular investigation and genetic characterization of feline leukemia virus (FeLV) in cats referred to a veterinary teaching hospital in Northern Italy
In this study, a quantitative SYBR Green Real-Time PCR (qPCR) assay was used to detect FeLV proviral DNA in blood samples from antigen positive cats referred to a veterinary teaching hospital in Northern Italy in 2018 –2021. To genetically characterize the identified viruses, a portion of the viral envelope (env) gene was amplified using six different end-point PCRs and sequenced. Twenty-two of 26 (84.6%) cats included in the study tested positive by qPCR assay. This suggests a high performance of the qPCR adopted but further studies are required to investigate the cause of discordant results between the antigen test and...
Source: Veterinary Research Communications - April 22, 2024 Category: Veterinary Research Source Type: research

Diagnosis, management, and outcomes of parechovirus infections in infants: an overview
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - April 22, 2024 Category: Microbiology Authors: Anjana SasidharanChristopher J. HarrisonRangaraj Selvarangan1Department of Pathology and Laboratory Medicine, Children ’s Mercy Hospital and Clinics, Kansas City, Missouri, USA2University of Missouri, College of Medicine, Kansas City, Missouri, USA Romn Source Type: research