Correction: Empaglifozin improves kidney senescence induced by D-galactose by reducing sirt1-mediated oxidative stress
Biogerontology. 2024 Apr 26. doi: 10.1007/s10522-024-10108-8. Online ahead of print.NO ABSTRACTPMID:38668818 | DOI:10.1007/s10522-024-10108-8 (Source: Biogerontology)
Source: Biogerontology - April 26, 2024 Category: Geriatrics Authors: Ronghua Fang Jie Chen Jiangchuan Long Binghan Zhang Qixuan Huang Shengbing Li Ke Li Qing Chen Dongfang Liu Source Type: research
'Too young to sit at home': a qualitative study conducted among employees with young-onset dementia and their relatives
CONCLUSION: The findings highlight a strong desire to work post-YOD diagnosis, serving as a foundation for developing workplace support tools and guidance. This has the potential to help individuals with YOD preserve their self-confidence and identity while working within their capabilities.PMID:38669151 | DOI:10.1080/13607863.2024.2345132 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 26, 2024 Category: Geriatrics Authors: Bo Smeets Niels Janssen Kirsten Peetoom Lizzy Boots Christian Bakker Marjolein de Vugt Source Type: research
Reminiscence interventions for loneliness reduction in older adults: a systematic review
CONCLUSION: While reminiscence interventions hold some promise for reducing loneliness levels among older adults, future methodologically rigorous research is required, and standardised protocols need to be developed for application, with the specific aim of reducing levels of loneliness among older adults.PMID:38669147 | DOI:10.1080/13607863.2024.2345809 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 26, 2024 Category: Geriatrics Authors: Andrea Castillo-Hornero Mario Rojano-Hidalgo Agust ín López Ana Alarc ón Oscar Belmonte Antonio Caballer Source Type: research
How can care home activities facilitate social connection in residents? A qualitative study
CONCLUSION: We identified the key aspects of activities which facilitate social connection in care homes. These findings can be applied to a range of existing and newly designed activities in care homes and inform the development and testing of psychosocial interventions aiming to improve social connection.PMID:38669150 | DOI:10.1080/13607863.2024.2345130 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 26, 2024 Category: Geriatrics Authors: Michal M Misiak Jennifer Bethell Hannah Chapman Andrew Sommerlad Source Type: research
Fragility Fractures: Preoperative assessment and optimisation
Z Gerontol Geriatr. 2024 Apr 26. doi: 10.1007/s00391-024-02299-z. Online ahead of print.ABSTRACTFragility fractures are associated with high morbidity and mortality. An interdisciplinary collaboration and an individualized, patient-centered approach are essential to ensure an optimized preoperative period and to improve perioperative safety. Preoperative responsibilities of trauma surgery include in the first step the identification of fragility fractures and the necessity for geriatric involvement. Orthogeriatric co-management (OCM) focuses on the identification of the medical, functional and social needs of the patient. ...
Source: Zeitschrift fur Gerontologie und Geriatrie - April 26, 2024 Category: Geriatrics Authors: Jan-Niklas Krohn Basel Habboub Markus Gosch Source Type: research
How PBPK Can Help to Understand Old Drugs and Inform their Dosing in Elderly: Amantadine Case Study
Clin Pharmacol Ther. 2024 Apr 26. doi: 10.1002/cpt.3276. Online ahead of print.ABSTRACTAmantadine, despite being on the market for 55 years, has several unknown aspects of its pharmacokinetics especially related to the influence of covariates such as age, disease, or interactions linked to amantadine's renal elimination. As amantadine is used in Parkinson's disease and is considered a potential candidate in COVID treatment and other diseases, there is an unmet need for thorough understanding of its pharmacokinetic in special populations, such as the elderly. We aimed to mechanistically describe amantadine pharmacokinetics ...
Source: Clinical Pharmacology and Therapeutics - April 26, 2024 Category: Drugs & Pharmacology Authors: Olha Shuklinova Sibylle Neuhoff Sebastian Polak Source Type: research
What is a presumed sign of life doing on a dead comet?
Scientists have discovered dimethyl sulfide (DMS), a molecule thought to have only living sources, on a cold, lifeless comet. The finding calls into question the molecule’s usefulness as a biosignature and the significance of an earlier hint of it in the atmosphere of an alien planet.
“This is the first sign of an abiotic source,” says Nora Hänni, a chemist at the University of Bern who
presented the discovery last week
at the General Assembly of the European Geosciences Union.
Tim Lichtenberg, a planetary astronomer at the University of Groningen who wasn
’t involved ...
Source: Science of Aging Knowledge Environment - April 26, 2024 Category: Geriatrics Source Type: research
Multicomponent perioperative interventions to improve outcomes for frail patients: a systematic review
Preoperative frailty is associated with increased risk of adverse outcomes. In 2017, McIsaac and colleagues ’ systematic review found that few interventions improved outcomes in this population and evidence was... (Source: BMC Geriatrics)
Source: BMC Geriatrics - April 26, 2024 Category: Geriatrics Authors: Vivian Ka-Yan Kwok, Natasha Reid, Ruth E Hubbard, Harshithaa Thavarajah and Emily H Gordon Tags: Research Source Type: research
Factors associated with the level of self-management in elderly patients with chronic diseases: a pathway analysis
To analyze the effects and pathways of factors such as psychological capital, family functioning, and sources of meaning in life on the level of self-management in elderly patients with chronic diseases and to... (Source: BMC Geriatrics)
Source: BMC Geriatrics - April 26, 2024 Category: Geriatrics Authors: Zhiyang Cong, Mingshu Huo, Xing Jiang and Hongyu Yu Tags: Research Source Type: research
Tailored videoconferencing counselling program to support family carers of people living with dementia during the transition to permanent residential care: a pilot and feasibility randomised trial
Decisions surrounding the permanent residential care placement of people living with dementia can be stressful and distressing; however, providing access to targeted information and support prior to placement ... (Source: BMC Geriatrics)
Source: BMC Geriatrics - April 26, 2024 Category: Geriatrics Authors: Deborah Brooks, Katy Wyles, Nancy A. Pachana, Elizabeth Beattie and Joseph E. Gaugler Tags: Research Source Type: research
News at a glance: Plants ’ tree of life, conserving U.S. federal lands, and entertaining invertebrate sentience
CONSERVATION
Interior Department boosts restoration
The largest manager of public lands in the United States last week announced it will manage them to promote ecological stewardship, while continuing to allow extractive commercial uses such as mining, oil drilling, and cattle grazing. The Bureau of Land Management (BLM) oversees nearly 1 million square kilometers of federal land, about 10% of the country’s landmass, mostly in Western states. Under a rule issued on 18 April,
BLM will now assess the ecological condition of all hectares it manages
, not just grazing land. The agency will a...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research
Traffic noise causes lifelong harm to baby birds
If you think it’s hard to chat next to a busy highway, try raising a nestling there. A new experiment on developing birds shows traffic noise can slow their growth and lead to lifelong impairments. The finding raises new concerns about the effect of noise pollution on wildlife—and humans as well.
“I’m surprised by these effects,” says Clinton Francis, an ecologist at California Polytechnic State University who was not involved in the work. He says the new paper,
published
today in
Science
, “provides very strong evidence for a direct impact of noise.”
Researchers already knew
...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research
A gene mutation turned these fish into intrepid explorers
The 240 species of cichlid fish in Africa’s Lake Tanganyika come in an astonishing variety of shapes and sizes, from the paper clip–size “sheller” that lives in abandoned snail shells to the nearly meter-long emperor cichlid. Biologists have long wondered what drove this burst of evolutionary creativity. Now, researchers have demonstrated what many suspected but had not been able to prove: that the behavior of an ancestral species—in this case, an appetite for exploration—set the stage for the rapid evolution.
The work, which appears today in
Science
, also
ties this behavioral trait to a...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research
Can science find ways to ease loneliness?
Related podcast
The science of loneliness, making one of organic chemistry’s oldest reactions safer, and a new book series
BY
Sarah Crespi
,
Kelly Servick
,
Ariana Remmel
,
Valerie Thompson
,
Angela Saini
Podcast
25 Apr 2024
One Wednesday in May 2023, a small group gathered at an outdoor café in Barcelona, Spain, sipping coffee in t...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research
Are Barriers to Physical Activity Associated With Changing Physical Activity Levels and Sedentary Time in Patients With Peripheral Arterial Disease? A Longitudinal Study
J Aging Phys Act. 2024 Apr 24:1-7. doi: 10.1123/japa.2023-0120. Online ahead of print.ABSTRACTThe aims of the current study were to analyze the association between the barriers to and changes in physical activity levels and sedentary behavior, as well as to examine whether these barriers change over time in patients with peripheral artery disease. In this longitudinal study, we assessed 72 patients (68% men; 65.7 ± 9.2 years). Physical activity was measured over a 7-day period using an accelerometer, and data were collected on time spent in sedentary activities, low-light physical activities, and moderate-to-vigorous phys...
Source: Journal of Aging and Physical Activity - April 25, 2024 Category: Geriatrics Authors: Juliane Carolina da Silva Santos Raphael Mendes Ritti-Dias Gabriel Grizzo Cucato Nelson Wolosker Marilia de Almeida Correia Breno Quintella Farah Source Type: research
