Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report
We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.PMID:38310437 | PMC:PMC10685829 | DOI:10.34172/aim.2023.53 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - February 4, 2024 Category: Middle East Health Authors: G ökmen Güzel Muhammer Ergen ç Source Type: research

Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report
We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.PMID:38310437 | PMC:PMC10685829 | DOI:10.34172/aim.2023.53 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - February 4, 2024 Category: Middle East Health Authors: G ökmen Güzel Muhammer Ergen ç Source Type: research

Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report
We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.PMID:38310437 | PMC:PMC10685829 | DOI:10.34172/aim.2023.53 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - February 4, 2024 Category: Middle East Health Authors: G ökmen Güzel Muhammer Ergen ç Source Type: research

Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report
We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.PMID:38310437 | PMC:PMC10685829 | DOI:10.34172/aim.2023.53 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - February 4, 2024 Category: Middle East Health Authors: G ökmen Güzel Muhammer Ergen ç Source Type: research

Linked-color imaging with or without artificial intelligence for adenoma detection: a randomized trial
Conclusions LCA was significantly superior to LCI alone in terms of ADR. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Endoscopy)
Source: Endoscopy - February 1, 2024 Category: Gastroenterology Authors: Miyaguchi, Kazuya Tsuzuki, Yoshikazu Hirooka, Nobutaka Matsumoto, Hisashi Ohgo, Hideki Nakamoto, Hidetomo Imaeda, Hiroyuki Tags: Original article Source Type: research

Cronkhite ‒Canada syndrome as inflammatory hamartomatous polyposis: new evidence from whole transcriptome sequencing of colonic polyps
Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary disease characterized by diffuse gastrointestinal polyposis and ectodermal abnormalities. Although it has been proposed to be a chronic inflammatory con... (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - February 1, 2024 Category: Internal Medicine Authors: Shuang Liu, Yunfei Zhi, Runfeng Zhang, Yan You, Wen You, Qiushi Xu, Jingnan Li and Ji Li Tags: Research Source Type: research

GSE244542 Single-cell landscape of the cellular microenvironment in three different colonic polyp subtypes in children
Contributors : Youcai Deng ; Yafei DengSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensscRNA-seq was applied to map the cellular landscape of colonic polyps from pediatric patients with SJP, JPS or PJS and aged-matched colonic tissues to help dissect polyp heterogeneity among different polyp subtypes and identify the underlying cellular and molecular events that may control disease outcome (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - January 31, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Device-assisted enteroscopy in the surveillance of intestinal hamartomas in Peutz-Jeghers syndrome
Conclusions Endoscopic management of small bowel polyps in patients with PJS using DAE is an effective strategy for prophylactic removal of hamartomas. DAE surveillance and endoscopic polypectomy is safe and may decrease the need for repeated laparotomy in patients with PJS. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - January 30, 2024 Category: Gastroenterology Authors: Mohamed Elfeky, Omar Wahid Panjwani, Suraj Cave, David Wild, Daniel Raines, Daniel Tags: Original article Source Type: research

An unusual manifestation of Langerhans cell histiocytosis in the gastrointestinal tract
We present the case of a 49-year-old woman with a previous diagnosis of LCH in 2018 with only cutaneous involvement, managed with topical corticosteroids. After developing hypertransaminasemia, a PET-CT scan was performed, showing dissemination of the disease with bone, hepatosplenic and gynecological involvement. In addition, hypermetabolic lesions were described in the cecum with ileocecal adenopathies. A colonoscopy was performed showing in the cecum and ascending colon multiple sessile polyps of 5-10mm with central fibrin-coated erosions, from which biopsies were obtained. Histology revealed typical features of LCH wit...
Source: Revista Espanola de Enfermedades Digestivas - January 29, 2024 Category: Gastroenterology Authors: Laura Ray ón Moreno Alberto P érez Garvin Bruno Bernardo Beatriz Merino Source Type: research

Pachydysostosis of the fibula in a case of familial adenomatous polyposis
We report a 17-year-old male, who presented with a non-progressive bowing of the right leg detected at 18 months of age caused by a fibula malformation (later characterized as pachydysostosis) and a large exophytic osteoma of the left radius, noticed at the age of 15 years, without gastrointestinal symptoms. There was no relevant family history. Detailed characterisation revealed multiple osteomas, skin lesions and dental abnormalities, raising the hypothesis of FAP. This diagnosis was confirmed by genetic testing [c.4406_4409dup p.(Ala1471Serfs*17) de novo mutation in the APC gene] and endoscopic investigation (multiple a...
Source: European Journal of Medical Genetics - January 29, 2024 Category: Genetics & Stem Cells Authors: Daniela Oliveira Sofia Maia In ês Balacó Paulo Coelho Susana Almeida Margarida Ven âncio Jorge Saraiva Gen Nishimura S érgio B Sousa Source Type: research

Investigation of cullin-3 gene expression changes in people with colorectal cancer and polyps in China
This study aims to investigate the expression level of the CUL3 gene in polyps and colorectal cancer. This cross-sectional study collected 300 colorectal tissue biopsy samples, including 40 tumor tissue samples, 73 precancerous lesions with their adjacent tissue, and 31 normal tissue samples. The expression of the CUL3 gene was investigated by the Real-time PCR method. There was no significant difference in CUL3 mRNA expression between polyp tissues and their adjacent samples (p = 0.41). Our results showed no statistically significant difference in CUL3 gene expression between tumor tissues and their adjacent thermal sampl...
Source: Cellular and Molecular Biology - January 27, 2024 Category: Molecular Biology Authors: Xiaoguo Wei Xin Zhao Xinyan Zhao Xiaoxiong Yang Source Type: research

Prevalence of Colonic Polyps in Patients Undergoing Kidney Transplant Evaluation: A Meta-Analysis and Systematic Review
CONCLUSIONS: Our results suggest an average or increased prevalence of polyps and adenomatous polyps in patients with chronic kidney disease undergoing colonoscopy during evaluation for kidney transplant. The pooled analysis of the studies comparing the end-stage renal disease population versus a matched control group indicates higher prevalence of adenomatous polyps in patients with end-stage renal disease. Multiple studies have shown that screening colonoscopy in this patient group is safe and does not delay kidney transplant evaluation or waitlistrates; hence, screening colonoscopy should be routinely considered.PMID:38...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - January 24, 2024 Category: Transplant Surgery Authors: Mahmoud Y Madi Fouad Jaber Laith Numan Manar Y Shahwan Gregory Sayuk Michael E Presti Jill E Elwing Ahmad Najdat Bazarbashi Antonio R Cheesman Wissam Kiwan Source Type: research

Impact of study design on adenoma detection in the evaluation of artificial intelligence-aided colonoscopy: a systematic review and meta-analysis
Randomized controlled trials (RCTs) have reported that artificial intelligence (AI) improves endoscopic polyp detection. Different methodologies, namely parallel and tandem designs, have been employed to evaluate the efficacy of AI-assisted colonoscopy in RCTs. Systematic reviews and meta-analyses have reported a pooled effect that includes both study designs. However, it is unclear whether there are inconsistencies in the reported results of these two designs. Here, we aimed to determine whether study characteristics moderate between-trial differences in outcomes when evaluating the effectiveness of AI-assisted polyp dete...
Source: Gastrointestinal Endoscopy - January 23, 2024 Category: Gastroenterology Authors: Michelle CM. Lee, Colleen H. Parker, Louis WC. Liu, Armin Farahvash, Thurarshen Jeyalingam Source Type: research

Impact of study design on adenoma detection in the evaluation of artificial intelligence –aided colonoscopy: a systematic review and meta-analysis
Randomized controlled trials (RCTs) have reported that artificial intelligence (AI) improves endoscopic polyp detection. Different methodologies —namely, parallel and tandem designs—have been used to evaluate the efficacy of AI-assisted colonoscopy in RCTs. Systematic reviews and meta-analyses have reported a pooled effect that includes both study designs. However, it is unclear whether there are inconsistencies in the reported results o f these 2 designs. Here, we aimed to determine whether study characteristics moderate between-trial differences in outcomes when evaluating the effectiveness of AI-assisted polyp detec...
Source: Gastrointestinal Endoscopy - January 23, 2024 Category: Gastroenterology Authors: Michelle C.M. Lee, Colleen H. Parker, Louis W.C. Liu, Armin Farahvash, Thurarshen Jeyalingam Tags: Systematic review and meta-analysis Source Type: research

Spatio-Temporal Feature Transformation Based Polyp Recognition for Automatic Detection: Higher Accuracy than Novice Endoscopists in Colorectal Polyp Detection and Diagnosis
ConclusionsThe STFT-based colon polyp detection model exhibits high accuracy in detecting polyps in colonoscopy videos, with a particular efficiency in detecting small polyps ( ≤ 0.5 cm)(0.902 vs. 0.70,P <  0.001). (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - January 20, 2024 Category: Gastroenterology Source Type: research