A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition
The market has been in the doldrums and it has been a tough year for fundraising, both for non-profits and biotech startups. The conferences have exhibited more of an academic focus as companies tightened belts and postponed investment rounds, while investors stayed home. Not that this halts the flow of hype for some projects, and nor has it slowed media commentary on the longevity industry as it presently stands. A few of the articles in that commmentary are even interesting to read! The field has grown and is more mature now than has ever been the case. Biotech of all forms is a challenging field with a high failure rate...
Source: Fight Aging! - December 29, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Gut Microbiome Differs in Characteristic Ways in Patients with Precancerous Colon Polyps
The gut microbiome changes with age, the relative abundance of microbial populations shifting in ways that appear connected to chronic inflammation and dysfunction of the intestinal epithelium and intestinal barrier function. Cancer of the colon is an important cause of human mortality, and there is some hope that finding ways to prevent or reverse gut microbiome aging, such as via fecal microbiota transplant from young individuals, will go some way to minimizing colon cancer incidence.
Colorectal cancer is the second leading cause of cancer-related death in the U.S., and rates of colorectal cancer are rising amon...
Source: Fight Aging! - June 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Weekly Overseas Health IT Links – 23rd July2022.
In this study, researchers sought to determine whether differences in occult hypoxemia treatment existed between people of different races.Occult hypoxemia was defined as arterial blood oxygen saturation of less than 88 percent despite a pulse oximetry reading of 92 percent or more.-----https://healthitsecurity.com/news/security-awareness-and-training-crucial-to-preventing-healthcare-phishing-attacksSecurity Awareness and Training Crucial to Preventing Healthcare Phishing AttacksSecurity awareness and training greatly decreased the likelihood of an employee falling for a healthcare phishing attack, KnowBe4 researchers foun...
Source: Australian Health Information Technology - July 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
AI Adoption in Healthcare Requires Better Approaches to Patient Data
The following is a guest article by Vanessa Braunstein, Healthcare Product Marketing Lead at NVIDIA.
Building great AI models in healthcare and life sciences requires lots of data that is diverse, well-labeled, and spans across different patient types.
However, as AI gains traction, there are still a number of bottlenecks that slow down the process of developing robust AI models such as patient privacy, access to data, and lack of clinical expertise to annotate data for training.
In order to overcome these barriers, data scientists and developers have developed new solutions such as federated learning paradigms, AI models ...
Source: EMR and HIPAA - June 28, 2022 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Federated Learning GDPR Health Data Ethics Health Data Privacy Healthcare AI Healthcare AI Ethics Healthcare Neural Source Type: blogs
Catheter-Deliverable Biomaterial Sealants: Interview with Natalie Artzi, Co-founder of BioDevek
BioDevek, a medtech company based in Cambridge, Massachusetts, has developed a biomaterial adhesive that acts to seal internal wounds and incisions. The material is designed to be sprayed through a catheter, and the primary application for the technology so far is to act as a sealant following colonic polyp resection.
At present, following polyp resection, surgeons can use polyp clips to seal the resection site, which can hamper wound healing, or use no sealant at all, leading to an open wound that comes with a risk of bleeding or other complications. This can lead to additional surgeries to correct the issue and is inc...
Source: Medgadget - November 30, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Materials Plastic Surgery BioDevek Source Type: blogs
Gastroenterology Embraces Artificial Intelligence
AI and machine learning have the potential to redefine the management of several GI disorders.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.Colonoscopy is one of the true success stories in modern medicine.Studies have demonstrated that colonoscopy screening detects the cancer at a much earlier stage, reducing the risk of invasive tumors and metastatic disease, andreducing mortality. However, while colorectal cancer is highly preventable, it is thethird leading cause of cancer-related deathsin the U.S. A...
Source: Life as a Healthcare CIO - October 13, 2021 Category: Information Technology Source Type: blogs
Reimagining the FDA ’s Role in Digital Medicine
In addition to evaluating the safety of software as a medical device (SaMD), the agency needs to devote more resources to evaluating its efficacy and quality.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.The FDA ’s approach to software as a medical device (SaMD) has been evolving. Consider a few examples.In 2018, IDx-DR, a software system used to improve screening for retinopathy, a common complication of diabetes that affects the eye, became the first AI-based medical device to receiveUS Food and Drug...
Source: Life as a Healthcare CIO - September 30, 2021 Category: Information Technology Source Type: blogs
GI Genius Polyp Detection System: Interview with Giovanni Di Napoli, President, Gastrointestinal at Medtronic
We recently reported on the de novo FDA clearance received by Medtronic for its GI Genius AI polyp detection system. The product is hugely flexible as it works with any video colonoscope and provides AI powered assistance for clinicians in identifying colorectal polyps during colonoscopies.
Medtronic reports that the system has significantly improved polyp detection rates, which should translate to better colorectal cancer patient outcomes through prompt diagnosis and early treatment.
As a clinician performs a colonoscopy the system analyzes the video data and highlights suspected polyps using a green box on the vid...
Source: Medgadget - May 13, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Source Type: blogs
FDA Clears First AI Polyp Detection System for Colonoscopies
Medtronic won FDA de novo clearance for its GI Genius endoscopy technology that can spot suspicious lesions during routine colonoscopy exams. The system works with any video colonoscope and can even process pre-recorded colonoscopies.
Even highly experienced gastroenterologists can miss a polyp while navigating through the colon. Computer vision technology can carefully process the entirety of every video frame to spot any irregularities associated with polyps. According to Medtronic, “the GI Genius module has demonstrated a 14% absolute increase in ADR [adenoma detection rate] compared to colonoscopy alone fo...
Source: Medgadget - April 15, 2021 Category: Medical Devices Authors: Medgadget Editors Tags: GI Source Type: blogs
Racial disparities and early-onset colorectal cancer: A call to action
Colorectal cancer (CRC) is the second leading cause of death from cancer in both men and women in the US. Thanks in large part to increased screening of those over age 50 in last decade, overall CRC rates have been falling among the general population. However, the incidence of CRC among younger individuals in the US is rising at an alarming rate. Over the past 20 years, the rate of CRC has increased by 2.2% per year in people under age 50. Hidden within these statistics are the significant disparities in CRC incidence and outcomes that exist for African Americans.
Compared to whites, African Americans have a 20% higher in...
Source: Harvard Health Blog - March 17, 2021 Category: Consumer Health News Authors: Andrew Chan, MD, MPH Tags: Cancer Digestive Disorders Health care disparities Source Type: blogs
Can I take something to prevent colorectal cancer?
Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. There is compelling evidence that screening to detect CRC early to find and remove precancerous polyps can reduce CRC mortality. However, screening has associated harms, including procedural complications, and inherent limitations. For example, colonoscopy, the most common screening tool in the US, is less effective in preventing cancers of the right, or ascending side, of the colon compared with cancers of the left, or descending, side of the colon.
Moreover, only 60% of US adults recommended for screening actually follow through. Ev...
Source: Harvard Health Blog - January 13, 2021 Category: Consumer Health News Authors: Andrew Chan, MD, MPH Tags: Cancer Prevention Screening Source Type: blogs
Medgadget ’s Best Medical Technologies of 2020
In conclusion, 2020 will certainly be remembered for a world stopped by an pandemic. It will also stand out as a time when people came together to innovate, adapt, and improve the world around them. We wish you all a happy New Year and look forward to better times ahead, together.
Flashbacks: Medgadget’s Best Medical Technologies of 2019; 2018; 2017; 2016; 2015 (Source: Medgadget)
Source: Medgadget - December 30, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Source Type: blogs
CRAZY AMERICA: Health Insurance Covers Testing When You Are Well But Not When You Are Sick
By HANS DUVEFELT
Insurance is the wrong word for what we have here. Our private health insurance system’s prioritization of sometimes frivolous screenings but non-coverage for common illnesses and emergencies is a travesty and an insult to typical American middle class families.
State Medicaid insurance for the underemployed has minimal copays of just a few dollars for doctor visits and medications. From my vantage point as a physician, it is the best insurance a patient can have. They cover almost everything and it is clear to me how to apply for exceptions or follow their step care requirements. I cannot...
Source: The Health Care Blog - December 9, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Source Type: blogs
Aspirin and breast cancer risk: How a wonder drug may become more wonderful
Aspirin has been called a wonder drug. And it’s easy to see why.
It’s inexpensive, its side effects are well-known and generally minor. And since it was developed in the 1890s, it’s been shown to provide a number of potential benefits, such as relieving pain, bringing down a fever, and preventing heart attacks and strokes. Over the last 20 years or so, the list of aspirin’s potential benefits has been growing. And it might be about to get even longer: did you know that aspirin may lower your risk of several types of cancer?
Studies of aspirin and cancer
A number of studies suggest that aspirin can lower the risk of...
Source: Harvard Health Blog - October 23, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Breast Cancer Health Source Type: blogs
