Bougie cap esophageal passage: A novel potential tool for calibration of  lumen diameter in eosinophilic esophagitis?
I read with great interest the recent article “Comparison of endoscopy and radiographic imaging for detection of esophageal inflammation and remodeling in adults with eosinophilic esophagitis” by Nelson et al.1 As discussed by Katzka2 in his accompanying editorial, adequate monitoring of eosinophilic esophagitis (EoE) remains troublesome in clinical practice, in particular assessment of luminal compromise as a reflection of fibrotic remodeling. Although endoscopy reliably grasps inflammatory markers of disease activity, fibrotic changes, especially in the common setting of more diffuse than focal...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Vincent Zimmer Tags: Letter to the Editor Source Type: research

Per-oral endoscopic myotomy in achalasia: Which way to go —anterior or posterior?
We read with great interest the article by Tan et  al1 wherein the authors have compared the efficacy and safety of per-oral endoscopic myotomy (POEM) by an anterior versus a posterior approach. The authors concluded that POEM is equally safe and effective when performed by an anterior or a posterior approach. In addition, the incidence of gastroe sophageal reflux disease (GERD) was equal in both groups (anterior, 26.7%; posterior, 33.3%). (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Zaheer Nabi, Mohan Ramchandani, D. Nageshwar Reddy Tags: Letter to the Editor Source Type: research

Worrisome endoscopic feature in the stomach of patients with familial adenomatous polyposis: the proximal white mucosal patch
Gastric adenocarcinoma (GC) is a recently reported cancer risk in Western patients with familial adenomatous polyposis (FAP).1,2 Most GCs in these FAP patients occur in an area of polyposis in the proximal gastric body or fundus.1 We previously demonstrated that Western FAP patients with GC were more likely than were non-GC FAP control patients to have high-risk endoscopic and histologic features, including a carpeting of proximal gastric polyposis, polypoid mounds of proximal polyps, large solitary polyps, and high-risk histologic features (pyloric gland adenoma, tubular adenoma, and fundic gland polyps with high-grade dy...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Nitin Das Kunnathu, Gautam N. Mankaney, Pamela J. Leone, Michael W. Cruise, James M. Church, Amit Bhatt, Carol A. Burke Tags: Letter to the Editor Source Type: research

No difference does not always mean equivalent
We read with great interest the article by Bang et  al,1 “Stent placement by EUS or ERCP for primary biliary decompression in pancreatic cancer: a randomized trial.” The authors concluded that EUS-guided biliary decompression (EUS-BD) is a practical alternative to ERCP for primary decompression in pancreatic cancer. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Kaumichi Kawakubo, Masaki Kuwatani, Naoya Sakamoto Tags: Letter to the Editor Source Type: research

EUS-guided biliary drainage versus ERCP for the primary treatment of malignant distal biliary obstruction: time for a large randomized study
We read with great interest the 2 randomized controlled studies1,2 comparing EUS-guided biliary drainage (EUS-BD) versus ERCP as primary treatment of distal malignant biliary obstruction. Despite different primary outcomes (adverse event rate for Bang et  al1 and stent patency duration for Park et al,2) both studies concluded that EUS-BD and ERCP were comparable regarding both primary outcomes and secondary outcomes (ie, technical and clinical success). However, although EUS-BD is a promising technique, we believe that both studies were not suff iciently powered to support their conclusion. (Source: Gas...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Leonardo Frazzoni, Lorenzo Fuccio, Alberto Larghi Tags: Letter to the Editor Source Type: research

Role of warfarin as a predictor of recurrent bleeding after negative small-bowel capsule endoscopy
We read with interest the recent publication by Yung et  al,1 who concluded that negative capsule endoscopy (CE) findings adequately demonstrate a subsequently low risk of rebleeding. This finding is important with regard to the treatment of patients with obscure GI bleeding (OGIB) and to risk stratification (Table 1, available online at www.giejournal .org). (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Ryota Niikura, Atsuo Yamada, Yoshihiro Hirata, Yoku Hayakawa, Hirobumi Suzuki, Shinzo Yamamoto, Mitsuhiro Fujishiro, Kazuhiko Koike Tags: Letter to the Editor Source Type: research

Use of N-acetylcysteine plus simethicone to improve mucosal visibility during upper GI endoscopy
We read with great interest the article by Monrroy et  al1 about the use of N-acetylcysteine (NAC) plus simethicone to improve mucosal visibility during upper GI endoscopy. The authors’ findings show that the use of NAC plus simethicone before upper GI endoscopy improves visibility of the gastric mucosa, reduces the volume of water needed, and may i ncrease the diagnostic yield of the examination. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Giancarlo Spinzi, Alida Andrealli, Francesco Simone Conforti Tags: Letter to the Editor Source Type: research

Response:
We thank Dr Frazzoni et  al1 for their comments on our article.2 The majority of published studies on EUS-guided biliary drainage included patients with previously failed ERCPs who had locally advanced or metastatic disease. In the present study, we included all patients with pancreatic cancer, both operable and inoperabl e. Because the rate of procedure-related adverse events in this patient subset is unknown, we powered the study to demonstrate a difference of around 25%. Our study cohort comprised patients who had not previously undergone instrumentation, in whom the mean common bile duct diameter was modest at 12 ...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Ji Young Bang, Shyam Varadarajulu Tags: Letter to the Editor Source Type: research

Response:
We would like to thank Dr Kawakubo et  al1 for the comments on our article.2 The sample size for this superiority randomized trial was performed for a 2-sided comparison at 80% power, type I error rate of 0.05, based on the primary outcome measure of adverse rates. Therefore, the null hypothesis (H0) was defined as there being no signi ficant difference in adverse event rates between EUS-guided biliary drainage (EUS-BD) and ERCP, and the alternative hypothesis (H1) was defined as a significant difference in adverse event rates between the 2 treatment modalities, without the direction of the difference being specified....
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Ji Young Bang, Shyam Varadarajulu Tags: Letter to the Editor Source Type: research

Response:
We sincerely appreciate the comments and questions raised by Nabi et  al1 regarding our article.2 On the basis of our findings, the short-term (follow-up duration, 9-21 months; mean, 15.5 months) treatment efficacy, manometry outcomes, and adverse events were comparable between the anterior and posterior myotomy groups. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Yuyong Tan, Jirong Huo, Deliang Liu Tags: Letter to the Editor Source Type: research

Meta-analysis evaluating colonoscopy novelties: mind the methodology!
Having read with interest the meta-analysis that examined the effects of technologic novelties in improving the adenoma detection rate (ADR) and adenoma miss rate (AMR) in colonoscopy,1 we noted that the authors combined in the analysis data from randomized and nonrandomized studies and pooled outcomes data from different study designs. Although the former practice is debatable, combining studies with different designs (parallel groups vs crossover) that measure different outcomes (ADR vs AMR) to calculate the effect size of ADR is questionable2; thus, the results of ADR effect size should be interpreted cautiously, in our...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Konstantinos Triantafyllou, Georgios Tziatzios, Paraskevas Gkolfakis Tags: Letter to the Editor Source Type: research

Biliary radiofrequency ablation: burning issues
Endoscopic treatment of biliary neoplasms is a frontier of ERCP. Endoscopists lack widely accepted, effective, and safe therapies that not only relieve obstruction but also control or cure intraductal neoplasia. Radiofrequency ablation (RFA) may enhance local management of biliary neoplasms and is simpler and easier to use than photodynamic therapy, but definitive studies establishing its  benefit are lacking. In this context, the study of Camus et al1 in this issue of Gastrointestinal Endoscopy provides the first prospectively collected evidence that RFA may cure intraductal extension of ampullary adenomas. (Sou...
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Vinay Chandrasekhara, Mark Topazian Tags: Original article Source Type: research

Response:
We appreciate the interest shown by Drs Triantafyllou, Tziatzios, and Gkolfakis1 in our article2 and consider their comments appropriate. As mentioned in the letter, in our analysis we used data from parallel and crossover studies, which directly evaluated the adenoma detection rate (ADR) and adenoma miss rate (AMR), respectively. For the ADR analysis, we included data from crossover studies for the final calculation, obtaining the raw data from the first pass in both arms to establish the ADR in each study, which essentially followed the ADR calculation principle used in the parallel studies. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Daniel Castaneda, Seth A. Gross Tags: Letter to the Editor Source Type: research

Response:
We would like to thank our colleagues from Cleveland, Das Kunnathu et  al,1 for their important study that evaluated the association between white mucosal patch (WMP) and gastric cancer in familial adenomatosis polyposis (FAP) patients and for their comments1 on our study.2 (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Mathieu Pioche, Laura Calavas, Jean-Christophe Saurin Tags: Letter to the Editor Source Type: research

Response:
We read with great interest the letter by Spinzi et  al1 commenting on our article2 and warning about simethicone and its potential harmful effect when it is used for GI endoscopy. We agree with their concerns based on reports of crystallization in the endoscope channels when simethicone is used in the water pump.3 The concentration of simethicone u sed varies and is not standardized, but frequently 10 to 20 mL (1-2 g) are poured into 1 liter of water. Then the water is flushed; applied on the mucosa covered with bubbles, mucus, or both; and directly suctioned. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Adolfo Parra-Blanco, Hugo Monrroy, Jose Ignacio Vargas, Roberto Candia, Robinson Gonzalez Tags: Letter to the Editor Source Type: research

Contents
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

Editors
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

Focus on...
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

ASGE update
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

In upcoming issues...
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

Information for readers
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Source Type: research

Continuing Medical Education Exam: September 2018
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 14, 2018 Category: Gastroenterology Authors: Karthik Ravi, William Ross, Ara Sahakian, Brian Weston, Prasad G. Iyer, Amit Rastogi, Michael B. Wallace Tags: CME examination Source Type: research

Endoscopic sinusotomy versus redo surgery for the treatment of chronic pouch anastomotic sinus in ulcerative colitis patients
Pouch sinus may be a serious adverse event in patients undergoing ileal pouch-anal anastomosis. The aim of this study was to compare endoscopic sinusotomy and redo pouch surgery in the management of pouch sinus. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 11, 2018 Category: Gastroenterology Authors: Nan Lan, Tracy H. Hull, Bo Shen Source Type: research

Utility of video capsule endoscopy for longitudinal monitoring of Crohn ’s disease activity in the small bowel: a prospective study
This prospective, multicenter study evaluated small-bowel capsule endoscopy (CE) for the longitudinal assessment of mucosal inflammation in subjects with Crohn ’s disease (CD). (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 6, 2018 Category: Gastroenterology Authors: Gil Y. Melmed, Marla C. Dubinsky, David T. Rubin, Mark Fleisher, Shabana F. Pasha, Atsushi Sakuraba, Felix Tiongco, Ira Shafran, Ignacio Fernandez-Urien, Bruno Rosa, Neofytos P. Papageorgiou, Jonathan A. Leighton Source Type: research

Spigelman Stage IV Duodenal Polyposis Does Not Precede a Majority of Duodenal Cancer Cases in Patients with Familial Adenomatous Polyposis
The greatest known risk factor for duodenal cancer in FAP is Spigelman Stage (SS) IV duodenal polyposis. Endoscopic surveillance is recommended in FAP patients with SS 0-IV and prophylactic duodenectomy should be considered in SS IV. Cancer occurs in patients without SS IV polyposis. We assessed the relationship of SS and other factors with duodenal cancer in FAP. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 3, 2018 Category: Gastroenterology Authors: Sushrut S. Thiruvengadam, Rocio Lopez, Margaret O ’Malley, Lisa LaGuardia, James M. Church, Matthew Kalady, R. Matthew Walsh, Carol A. Burke Source Type: research

EUS-guided antegrade intervention for benign biliary diseases in patients with surgically altered anatomy (with videos)
Although balloon enteroscopy-assisted ERCP (BE-ERCP) is effective and safe for benign biliary diseases in patients with surgically altered anatomy (SAA), BE-ERCP is not always successful. Recently, EUS-guided antegrade intervention (EUS-AI) including a 1-stage or 2-stage procedure has been developed for BE-ERCP failure cases. The aim of the present study was to evaluate the outcome of EUS-AI for benign biliary diseases with SAA. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 1, 2018 Category: Gastroenterology Authors: Shuntaro Mukai, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Mitsuru Fujita, Kenjiro Yamamoto, Yuichi Nagakawa Source Type: research

Radiofrequency ablation compared with argon plasma coagulation after endoscopic resection of high-grade dysplasia or T1 adenocarcinoma in Barrett ’s esophagus: a randomized pilot study (BRIDE)
Endoscopic resection (ER) is safe and effective for Barrett ’s esophagus (BE) containing high-grade dysplasia (HGD) or mucosal adenocarcinoma (T1A); risk of metachronous neoplasia is reduced by ablation of residual BE using radiofrequency ablation (RFA) or argon plasma coagulation (APC). These have not been directly compared. We aimed to recruit up to 100 patients with BE and HGD or T1A confirmed by ER over 1 year in 6 centres in a randomized pilot study. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 1, 2018 Category: Gastroenterology Authors: Mohammad Farhad Peerally, Pradeep Bhandari, Krish Ragunath, Hugh Barr, Rehan Haidry, Laurence Lovat, Howard Smart, Rebecca Harrison, Clive Stokes, Karen Smith, Tom Morris, John S. de Caestecker Source Type: research

Performance Indicators in Colonoscopy after Certification for Independent Practice: Outcomes and Predictors of Competence
Robust real-world performance data of newly independent colonoscopists are lacking. In the United Kingdom, provisional colonoscopy certification (PCC) marks the transition from training to newly independent practice. We aimed to assess changes in key performance indicators (KPIs) such as cecal intubation rate (CIR) in the periods pre- and post-PCC, particularly regarding rates and predictors of trainees exhibiting a drop-in performance (DIP), defined as CIR (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 1, 2018 Category: Gastroenterology Authors: Keith Siau, James Hodson, Roland M. Valori, Stephen T. Ward, Paul Dunckley Source Type: research

Choosing the right through-the-scope clip: a rigorous comparison of rotatability, whip, open/close precision, and closure strength (with videos)
Many new through-the-scope (TTS) clips are available, and physicians often select clips based on physical characteristics and/or cost However, functional profiles may be equally important and have not been methodically assessed. We evaluated 5 commercially available clips: Resolution 360, Instinct, Quick Clip Pro, Dura Clip, and SureClip. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 26, 2018 Category: Gastroenterology Authors: Thomas J. Wang, Hiroyuki Aihara, Andrew C. Thompson, Allison R. Schulman, Christopher C. Thompson, Marvin Ryou Source Type: research

Detection of mesenteric ischemia by means of endoscopic visible light spectroscopy after luminal feeding
Endoscopic visible light spectroscopy (VLS) enables measurement of mucosal oxygen saturation during upper GI endoscopy and is used in the diagnostic work-up of chronic mesenteric ischemia (CMI). Currently, VLS is performed when the patient has fasted. We aimed to determine whether food challenge improves the diagnostic performance of VLS measurements for the diagnosis of CMI. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 25, 2018 Category: Gastroenterology Authors: Louisa J.D. van Dijk, Jihan Harki, Desir ée van Noord, Annemarie C. de Vries, Adriaan Moelker, Hence J.M. Verhagen, Ernst J. Kuipers, Marco J. Bruno Source Type: research

Clinical impact of closure of the mucosal defect after duodenal endoscopic submucosal dissection
Delayed adverse events (bleeding or perforation) are major concerns associated with duodenal endoscopic submucosal dissection (ESD). The aim of this study was to assess the efficacy of prophylactic closure of the mucosal defect after duodenal ESD. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 25, 2018 Category: Gastroenterology Authors: Motohiko Kato, Yasutoshi Ochiai, Seiichiro Fukuhara, Tadateru Maehata, Motoki Sasaki, Yoshiyuki Kiguchi, Teppei Akimoto, Ai Fujimoto, Atsushi Nakayama, Takanori Kanai, Naohisa Yahagi Source Type: research

Risk Assessment of Lymph Node Metastases in Early Gastric Adenocarcinoma Fulfilling Expanded Endoscopic Resection Criteria
Early gastric cancer (EGC) is known to present a low rate of lymph node metastases (LNMs). Gastrectomy with D2 lymphadenectomy is usually curative for EGC. Endoscopic submucosal dissection (ESD) is a well-accepted treatment modality for lesions that meet the classic criteria: those mucosal differentiated adenocarcinoma measuring 20 mm or less, without ulceration. Expanded criteria for ESD have been proposed based on null LNM rate from large gastrectomies series from Japan. Patients with LNM have been reported in Western centers, emerging the need for validation of expanded criteria. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 24, 2018 Category: Gastroenterology Authors: Fernanda Cristina Sim ões Pessorrusso, Aloisio Felipe-Silva, Carlos Eduardo Jacob, Marcus Fernando Kodama Pertille Ramos, Venancio Avancini Alves Ferreira, Evandro Sobroza de Mello, Bruno Zilberstein, Ulysses Ribeiro, Fauze Maluf-Filho Source Type: research

The retrievable puncture anchor traction method for EUS-guided gallbladder drainage: a porcine study
EUS-guided gallbladder drainage (EUS-GBD) is a challenging technique for endoscopists that requires a high level of skill. A very important reason why EUS-GBD is challenging is that the gallbladder can be easily collapsed. In order to resolve this concern, we aimed to develop a retrievable puncture anchor traction (RPAT) method for EUS-GBD. We evaluated and compared the success rate, safety, and outcomes of the RPAT method for EUS-GBD against EUS-GBD without retrievable puncture anchor using a porcine model. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 23, 2018 Category: Gastroenterology Authors: Kai Zhang, Siyu Sun, Jintao Guo, Sheng Wang, Nan Ge, Xiang Liu, Guoxin Wang Source Type: research

Impact of water exchange colonoscopy on endoscopy room efficiency: a systematic review and meta-analysis
Separate randomized controlled trials (RCTs) showed water exchange (WE) colonoscopy outperformed other techniques in minimizing insertion pain and optimizing adenoma detection rate. Longer insertion time required for removal of infused water, residual air and feces might have hampered its wider adoption. We evaluate the impact of WE compared with air or carbon dioxide insufflation (GAS) on room turnaround efficiency measured by cecal intubation, withdrawal and total procedure time. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 23, 2018 Category: Gastroenterology Authors: Sergio Cadoni, Cesare Hassan, Leonardo Frazzoni, Sauid Ishaq, Felix W. Leung Source Type: research

Burkitt lymphoma of the stomach in an immunocompetent patient
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Dorra Trad, Bibani Norsaf, Sabbah Meriam, Ouakaa Asma, Ben Brahim Ehsen Source Type: research

Atrophy or cancer? That is the question
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Lianjun Di, Kuang-I. Fu, Rui Xie, Xinglong Wu, Biguang Tuo Source Type: research

Disappearance of a tumor that completely covered the appendiceal orifice by endoloop-assisted endoscopic strangulation
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Tomoaki Tashima, Kouichi Nonaka, Shomei Ryozawa, Yuki Tanisaka Source Type: research

Radiation Gastritis After Yttrium-90 Radioembolization
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Shana Kothari, Yanxia Li, Charles Berkelhammer, Tarek Almouradi Source Type: research

Esophageal tuberculosis: a cause of dysphagia we should be aware of
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Alfonso Elosua Gonz ález, Elena Macías Mendizábal, Cristina Saldaña Dueñas, Ignacio Fernández-Urién Sainz, Juan J. Vila Costas Source Type: research

Long-term recurrent bleeding risk after endoscopic therapy for definitive colonic diverticular bleeding: band ligation versus clipping
This study sought to elucidate the recurrent bleeding risk of endoscopic band ligation versus clipping for definitive CDB based on stigmata of recent hemorrhage (SRH). (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 20, 2018 Category: Gastroenterology Authors: Naoyoshi Nagata, Naoki Ishii, Mitsuru Kaise, Takuro Shimbo, Toshiyuki Sakurai, Junichi Akiyama, Naomi Uemura Source Type: research

Computerized feedback during colonoscopy training leads to improved performance: a randomized trial
Simulation-based training in colonoscopy is increasingly replacing the traditional apprenticeship method to avoid patient-related risk. Mentoring during simulation is necessary to provide feedback and to motivate, but expert supervisors are a scarce resource. We aimed to determine whether computerized feedback in simulated colonoscopy would improve performance, optimize time spent practicing, and optimize the pattern of training. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2018 Category: Gastroenterology Authors: Andreas Slot Vilmann, David Norsk, Morten Bo S øndergaard Svendsen, Rasmus Reinhold, Lars Bo Svendsen, Yoon Soo Park, Lars Konge Source Type: research

Tethered capsule endomicroscopy for unsedated microscopic imaging of the esophagus, stomach, and duodenum in humans (with video)
Patients with many different digestive diseases undergo repeated esophagogastroduodenoscopy throughout their life. Tethered capsule endomicroscopy (TCE) is a less invasive method for obtaining high-resolution images of the gastrointestinal mucosa for diagnosis and treatment planning of diseases. In this paper, we present our results from a single center, aimed at testing the safety and the feasibility of TCE for imaging the esophagus, stomach, and duodenum. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2018 Category: Gastroenterology Authors: Michalina J. Gora, Lucille Qu énéhervé, Robert W. Carruth, Weina Lu, Mireille Rosenberg, Jenny S. Sauk, Alessio Fasano, Gregory Y. Lauwers, Norman S. Nishioka, Guillermo J. Tearney Source Type: research

Impact of fellow training level on adverse events and operative time for common pediatric GI endoscopic procedures
Previous studies on pediatric endoscopic training have not examined if adverse events (AEs) are affected by the fellow ’s training level in detail. We aimed to determine whether trainee presence and educational level increases AEs or operative time (OT) for pediatric intestinal endoscopy. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2018 Category: Gastroenterology Authors: Jacob A. Mark, Robert E. Kramer Source Type: research

Collision of early cancer and mucosa-associated lymphoid tissue lymphoma in Helicobacter pylori-eradicated stomach
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2018 Category: Gastroenterology Authors: Yosuke Toya, Shotaro Nakamura, Yasuko Fujita, Tamotsu Sugai, Takayuki Matsumoto Source Type: research

A rare cause of gastric “volvulus”
(Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2018 Category: Gastroenterology Authors: Fei Chen, Xiaoli Jin, Yang Guo, Liangjing Wang Source Type: research

Laparoscopic magnetic sphincter augmentation versus double-dose proton pump inhibitors for management of moderate-to-severe regurgitation in GERD: a randomized controlled trial
GERD patients frequently complain of regurgitation of gastric contents. Medical therapy with proton-pump inhibitors (PPIs) is frequently ineffective in alleviating regurgitation symptoms, as PPIs do nothing to restore a weak lower esophageal sphincter. Our aim was to compare effectiveness of increased PPI dosing with laparoscopic magnetic sphincter augmentation (MSA) in patients with moderate-to-severe regurgitation despite once-daily PPI therapy. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 18, 2018 Category: Gastroenterology Authors: R.C. Bell, J.C. Lipham, B.E. Louie, V.A. Williams, J.D. Luketich, M.A. Hill, W.O. Richards, C.M. Dunst, D.G. Lister, L.E. McDowell-Jacobs, P.R. Reardon, K.L. Woods, J.C. Gould, F. Buckley, S.N. Kothari, L. Khaitan, C.D. Smith, A. Park, C.C. Smith, G.R. Ja Source Type: research

Aspiring to inspIRE: catheter-directed electrical therapy and biliary metal stent patency
In the January issue of Gastrointestinal Endoscopy, Ueshima et  al1 describe the feasibility and safety of catheter-directed irreversible electroporation (IRE) of a normal common bile duct (CBD) in an animal model. The authors report the results of their initial experience with a novel catheter (20 mm long, 7F) using a modified 240-cm balloon dilation cathete r, which serves as a monopolar device to perform direct IRE at 2000 V, 90 pulses, and 100-μs pulse. On the basis of these preliminary results. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 14, 2018 Category: Gastroenterology Authors: Meir Mizrahi, Jonah Cohen, Douglas Pleskow Tags: Original article Source Type: research

Antimicrobial decontamination of endoscopes: Are we there  yet?
The growth of GI endoscopy provision globally has mirrored developments in the management of GI disease. Endoscopic procedures have become increasingly complex and are often performed in critically ill patients. All endoscopes have the potential to harbor and transmit pathogens, which could cause lethal healthcare-associated infections (HAIs). Data from the Centers for Disease Control and Prevention (CDC) suggest that the prevalence of HAIs has been on the decline.1 Endoscopy is generally safe, and HAIs associated with endoscopy have been uncommon despite the volume of procedures performed annually. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 14, 2018 Category: Gastroenterology Authors: Shyam Menon Tags: Original article Source Type: research

Importance of timely eradication of Helicobacter pylori to prevent peptic ulcer recurrence and gastric cancer
Helicobacter pylori infection has long been identified as one of the most important risk factors for the development of peptic ulcer and gastric cancer. Eradication of H pylori infection has also been found to reduce the recurrence of peptic ulcers and lower the risk of gastric cancer.1-3 In the article in this issue of Gastrointestinal Endoscopy, Sverden et  al4 report their results from a population-based study regarding the effect of delaying H pylori eradication on the risk of the development of recurrent peptic ulcer and gastric cancer. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 14, 2018 Category: Gastroenterology Authors: Hon Chi Yip, Anthony Yuen Bun Teoh Tags: Original article Source Type: research

Duodenoscope-related and echoendoscope-related infections: Is “never” possible?
In 1999, the term “never event” was introduced by the National Quality Forum (NQF) to refer to particularly egregious and entirely preventable errors such as wrong-site surgery.1 The NQF more recently transitioned toward using the slightly more flexible term “serious reportable events” to describe events tha t are “unambiguous, usually preventable, serious,” “indicative of a problem in a health care facility's safety systems,” and/or “important for public credibility or…accountability.”2 The widely reported duodenoscope-related outbreaks in the past se...
Source: Gastrointestinal Endoscopy - July 14, 2018 Category: Gastroenterology Authors: Tyler M. Berzin, Joseph D. Feuerstein Tags: Original article Source Type: research