Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage
CONCLUSIONS: Our findings suggest a relationship among altered fecal α-glucosidase levels, the presence of intestinal mucosal lesions, which can be precursors of CRC, and shifts in defined microbial groups of the fecal microbiota.PMID:38614290 | DOI:10.1016/j.anaerobe.2024.102853 (Source: Anaerobe)
Source: Anaerobe - April 13, 2024 Category: Microbiology Authors: Sergio Ruiz-Saavedra Nuria Salazar Adolfo Su árez Ylenia Diaz Carmen Gonz ález Del Rey Sonia Gonz ález Clara G de Los Reyes-Gavil án Source Type: research
Management of Rectal Cancer in Lynch Syndrome: Balancing Risk Reduction and Quality of Life
Clin Colon Rectal Surg. 2023 Aug 10;37(3):180-184. doi: 10.1055/s-0043-1770730. eCollection 2024 May.ABSTRACTPatients with Lynch syndrome are predisposed to developing colorectal cancer and a variety of extracolonic malignancies, at a young age. The management of rectal cancer in the setting of Lynch syndrome is a complex clinical scenario that requires the expertise of a multidisciplinary management team. In this review, we delve into the approach for rectal cancer in these patients, and specifically focus on several key aspects of treatment. Some unique aspects of rectal cancer in Lynch syndrome include the decision betw...
Source: Clinical Colorectal Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Bradley A Krasnick Matthew F Kalady Source Type: research
Management of Rectal Cancer in Lynch Syndrome: Balancing Risk Reduction and Quality of Life
Clin Colon Rectal Surg. 2023 Aug 10;37(3):180-184. doi: 10.1055/s-0043-1770730. eCollection 2024 May.ABSTRACTPatients with Lynch syndrome are predisposed to developing colorectal cancer and a variety of extracolonic malignancies, at a young age. The management of rectal cancer in the setting of Lynch syndrome is a complex clinical scenario that requires the expertise of a multidisciplinary management team. In this review, we delve into the approach for rectal cancer in these patients, and specifically focus on several key aspects of treatment. Some unique aspects of rectal cancer in Lynch syndrome include the decision betw...
Source: Clinical Colorectal Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Bradley A Krasnick Matthew F Kalady Source Type: research
Evaluation of EGFR and COX pathway inhibition in human colon organoids of serrated polyposis and other hereditary cancer syndromes
This study examined effects of EGFR and COX pathway inhibition in organoid cultures derived from uninvolved colon and polyps of SPS patients. We also compared with organoids representing the hereditary gastrointestinal syndromes, Familial Adenomatous Polyposis (FAP) and Lynch syndrome (LS). Eighteen total organoid colon cultures were generated from uninvolved colon and polyps in SPS, FAP, LS, and non-syndromic screening colonoscopy patients.BRAF andKRAS mutation status was determined for each culture. Erlotinib (EGFR inhibitor) and sulindac (COX inhibitor) were applied individually and in combination. A 44-target gene cust...
Source: Familial Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
Unrestricted vs 3-day low-residue diet for colonoscopy preparation. Results of a feasibility randomized trial
CONCLUSIONS: It is feasible to test the impact of an unrestricted diet for adequate bowel preparation. Comparable cleansing results were achieved, but the unrestricted diet showed better tolerability.PMID:38591600 | DOI:10.17235/reed.2024.10417/2024 (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - April 9, 2024 Category: Gastroenterology Authors: Salvador Machlab Mashlab Eva Mart ínez-Bauer Pilar L ópez Mar ía Del Mar Pujals Fernando Fern ández-Bañares Anna Selva Xavier Calvet Rafel Campo Source Type: research
Efficacy and Safety of Thermal Ablation after Endoscopic Mucosal Resection: A Systematic Review and Network Meta-Analysis
Conclusions: We demonstrated the efficacy and safety of thermal ablation after EMR for decreasing recurrence of adenoma.PMID:38592137 | PMC:PMC10932371 | DOI:10.3390/jcm13051298 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 9, 2024 Category: Cancer & Oncology Authors: Hossein Haghbin Nuruddinkhodja Zakirkhodjaev Rawish Fatima Faisal Kamal Muhammad Aziz Source Type: research
Unrestricted vs 3-day low-residue diet for colonoscopy preparation. Results of a feasibility randomized trial
CONCLUSIONS: It is feasible to test the impact of an unrestricted diet for adequate bowel preparation. Comparable cleansing results were achieved, but the unrestricted diet showed better tolerability.PMID:38591600 | DOI:10.17235/reed.2024.10417/2024 (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - April 9, 2024 Category: Gastroenterology Authors: Salvador Machlab Mashlab Eva Mart ínez-Bauer Pilar L ópez Mar ía Del Mar Pujals Fernando Fern ández-Bañares Anna Selva Xavier Calvet Rafel Campo Source Type: research
