Enhancing endoscopic measurement: validating a quantitative method for polyp size and location estimation in upper gastrointestinal endoscopy
ConclusionsThe proposed method of measurements of polyp size and location was found to be highly accurate, offering great potential for clinical implementation to improve polyp assessment. This level of performance represents a notable improvement over visual estimation technique used in clinical practice. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - March 11, 2024 Category: Surgery Source Type: research

Efficacy and safety of esketamine combined with propofol for curative endoscopic resection in colorectum: a prospective, randomized controlled trial
Curative endoscopic resection is widely used to treat colonic polyps and early stage cancers. The anesthetic strategy commonly involves the use of propofol combined with a small dose of opioids for sedation. A... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - March 9, 2024 Category: Anesthesiology Authors: Yimei Ma, Jiali Wang, Yuying Yang and Minmin Yao Tags: Research Source Type: research

The histologic features, molecular features, detection and management of serrated polyps: a review
This article provides a comprehensive summary of the epidemiology, histologic features, molecular features, and detection methods for various serrated polyps, along with recommendations for their management and surveillance. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 7, 2024 Category: Cancer & Oncology Source Type: research

Underwater versus conventional endoscopic mucosal resection for ≥10 mm sessile or flat colorectal polyps: A systematic review and meta-analysis
by Xue Wang, Yue Wang, Xueyan Cao, Chunmei Zhang, Lin Miao Background and aimUnderwater endoscopic mucosal resection (UEMR) has been an emerging substitute for conventional EMR (CEMR). This systematic review and meta-analysis aimed at comparing the efficiency and safety of the two techniques for removing ≥10 mm sessile or flat colorectal polyps. MethodsPubMed, Cochrane Library and Embase databases were searched up to February 2023 to identify eligible studies that compared the outcomes of UEMR and CEMR. This meta-analysis was conducted on the en bloc resection rate, R0 resection rate, complete resection rate, procedure t...
Source: PLoS One - March 7, 2024 Category: Biomedical Science Authors: Xue Wang Source Type: research

A colonial serrated polyp classification model using white-light ordinary endoscopy images with an artificial intelligence model and TensorFlow chart
In this study, we implemented a combination of data augmentation and artificial intelligence (AI) model —Convolutional Neural Network (CNN)—to help physicians classify colonic polyps into traditional adenoma (T... (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - March 5, 2024 Category: Gastroenterology Authors: Tsung-Hsing Chen, Yu-Tzu Wang, Chi-Huan Wu, Chang-Fu Kuo, Hao-Tsai Cheng, Shu-Wei Huang and Chieh Lee Tags: Research Source Type: research

Peutz –Jeghers syndrome with polyps in the stomach, duodenum, and small and large intestine: a case report
ConclusionTimely polyp removal and lifelong surveillance are crucial in managing Peutz –Jeghers syndrome. Further research and genetic analysis are needed to improve understanding and management of this rare disorder. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 5, 2024 Category: General Medicine Source Type: research

Efficient organized colorectal cancer screening in Shenzhen: a microsimulation modelling study
CONCLUSION: This study identifies efficient CRC screening strategies for the average-risk population in Shenzhen. Most efficient screening strategies indeed start at age 40, but the optimal starting age depends on the chosen willingness-to-pay threshold. Within insufficient colonoscopy resources, efficient FIT and NCPCS screening strategies might be CRC initial screening strategies. We acknowledged the age-dependency bias of the results with NCPCS and RS.PMID:38429684 | DOI:10.1186/s12889-024-18201-w (Source: Cancer Control)
Source: Cancer Control - March 1, 2024 Category: Cancer & Oncology Authors: Minmin Zhu Xuan Zhong Tong Liao Xiaolin Peng Lin Lei Ji Peng Yong Cao Source Type: research

GSE199173 Specific serum methylome of the serrated pathway of colorectal carcinogenesis
This study was conducted to explore the serum methylome of precancerous lesions belonging to the serrated pathway of colorectal carcinogenesis in a prospective multicentre cohort. Individuals were grouped into five main categories: (i) serrated adenocarcinoma (SAC), (ii) high-risk serrated polyps (HR-SP) comprising traditional serrated adenomas (TSA), sessile serrated lesions (SSL), and serrated polyps (SP) with dysplasia or ≥ 10 mm; (iii) high-risk hyperplastic polyps (HR-HP), defined as HP ≥ 10 mm; (iv) low-risk serrated lesions (LR-SL) including SP without dysplasia< 10 mm and HP< 10 mm; and (v) healthy individuals ...
Source: GEO: Gene Expression Omnibus - March 1, 2024 Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research

Older Woman With Proptosis, Ptosis, and Blurred Vision
A woman in her early 70s with a history of coronary artery disease, hypertension, and colon polyps presented to oculoplastic surgery with 1 week of progressive right-sided proptosis, headache, right eyelid ptosis, and blurry vision. Outside magnetic resonance imaging demonstrated an infiltrative mass involving right greater than left orbital apices, the right optic nerve, and right extraocular muscles. What would you do next? (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - March 1, 2024 Category: Opthalmology Source Type: research

Population-based screening for colorectal cancer in Wuhan, China
In conclusion, preliminary real-world evidence suggested that fecal DNA tests had promising diagnostic yield in population-based CRC screening.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=192838, identifier ChiCTR2300070520. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 29, 2024 Category: Cancer & Oncology Source Type: research

Bridging the Diagnostic Gap: How Autonomous Artificial Intelligence Can Assist in Endoscopic Diagnosis of Experts
I read with interest the article by Djinbachian et  al1 comparing autonomous artificial intelligence (AI) with AI-assisted human optical diagnosis of colorectal polyps. It is an important contribution, and additional perspectives regarding implementation into clinical practice deserve discussion. (Source: Gastroenterology)
Source: Gastroenterology - February 29, 2024 Category: Gastroenterology Authors: Hantong Hu Tags: Correspondence Source Type: research