Botanicals as promising antimicrobial agents for enhancing oral health: a comprehensive review
Crit Rev Microbiol. 2024 Mar 28:1-24. doi: 10.1080/1040841X.2024.2321489. Online ahead of print.ABSTRACTThe mouth houses the second largest diversity of microorganisms in the body, harboring more than 700 bacterial species colonizing the soft mucosa and hard tooth surfaces. Microbes are the cause of several health-related problems, such as dental carries, gingivitis, periodontitis, etc., in the mouth across different age groups and socioeconomic/demographic groups. Oral infections are major health problems that affect the standard of living. Compromised oral health is related to chronic conditions and systemic disorders. M...
Source: Critical Reviews in Microbiology - March 28, 2024 Category: Microbiology Authors: Ekta Narwal Jairam Choudhary Manoj Kumar Ryszard Amarowicz Sunil Kumar None Radha Deepak Chandran Sangram Dhumal Surinder Singh Marisennayya Senapathy Sureshkumar Rajalingam Muthamilselvan Muthukumar Mohamed Mekhemar Source Type: research
Botanicals as promising antimicrobial agents for enhancing oral health: a comprehensive review
Crit Rev Microbiol. 2024 Mar 28:1-24. doi: 10.1080/1040841X.2024.2321489. Online ahead of print.ABSTRACTThe mouth houses the second largest diversity of microorganisms in the body, harboring more than 700 bacterial species colonizing the soft mucosa and hard tooth surfaces. Microbes are the cause of several health-related problems, such as dental carries, gingivitis, periodontitis, etc., in the mouth across different age groups and socioeconomic/demographic groups. Oral infections are major health problems that affect the standard of living. Compromised oral health is related to chronic conditions and systemic disorders. M...
Source: Critical Reviews in Microbiology - March 28, 2024 Category: Microbiology Authors: Ekta Narwal Jairam Choudhary Manoj Kumar Ryszard Amarowicz Sunil Kumar None Radha Deepak Chandran Sangram Dhumal Surinder Singh Marisennayya Senapathy Sureshkumar Rajalingam Muthamilselvan Muthukumar Mohamed Mekhemar Source Type: research
Botanicals as promising antimicrobial agents for enhancing oral health: a comprehensive review
Crit Rev Microbiol. 2024 Mar 28:1-24. doi: 10.1080/1040841X.2024.2321489. Online ahead of print.ABSTRACTThe mouth houses the second largest diversity of microorganisms in the body, harboring more than 700 bacterial species colonizing the soft mucosa and hard tooth surfaces. Microbes are the cause of several health-related problems, such as dental carries, gingivitis, periodontitis, etc., in the mouth across different age groups and socioeconomic/demographic groups. Oral infections are major health problems that affect the standard of living. Compromised oral health is related to chronic conditions and systemic disorders. M...
Source: Critical Reviews in Microbiology - March 28, 2024 Category: Microbiology Authors: Ekta Narwal Jairam Choudhary Manoj Kumar Ryszard Amarowicz Sunil Kumar None Radha Deepak Chandran Sangram Dhumal Surinder Singh Marisennayya Senapathy Sureshkumar Rajalingam Muthamilselvan Muthukumar Mohamed Mekhemar Source Type: research
Botanicals as promising antimicrobial agents for enhancing oral health: a comprehensive review
Crit Rev Microbiol. 2024 Mar 28:1-24. doi: 10.1080/1040841X.2024.2321489. Online ahead of print.ABSTRACTThe mouth houses the second largest diversity of microorganisms in the body, harboring more than 700 bacterial species colonizing the soft mucosa and hard tooth surfaces. Microbes are the cause of several health-related problems, such as dental carries, gingivitis, periodontitis, etc., in the mouth across different age groups and socioeconomic/demographic groups. Oral infections are major health problems that affect the standard of living. Compromised oral health is related to chronic conditions and systemic disorders. M...
Source: Critical Reviews in Microbiology - March 28, 2024 Category: Microbiology Authors: Ekta Narwal Jairam Choudhary Manoj Kumar Ryszard Amarowicz Sunil Kumar None Radha Deepak Chandran Sangram Dhumal Surinder Singh Marisennayya Senapathy Sureshkumar Rajalingam Muthamilselvan Muthukumar Mohamed Mekhemar Source Type: research
Cancer invasion and anaerobic bacteria: new insights into mechanisms
J Med Microbiol. 2024 Mar;73(3). doi: 10.1099/jmm.0.001817.ABSTRACTThere is growing evidence that altered microbiota abundance of a range of specific anaerobic bacteria are associated with cancer, including Peptoniphilus spp., Porphyromonas spp., Fusobacterium spp., Fenollaria spp., Prevotella spp., Sneathia spp., Veillonella spp. and Anaerococcus spp. linked to multiple cancer types. In this review we explore these pathogenic associations. The mechanisms by which bacteria are known or predicted to interact with human cells are reviewed and we present an overview of the interlinked mechanisms and hypotheses of how multiple...
Source: Journal of Medical Microbiology - March 27, 2024 Category: Microbiology Authors: Rachel Hurst Daniel S Brewer Abraham Gihawi John Wain Colin S Cooper Source Type: research
Fusobacterium nucleatum induces chemoresistance in colorectal cancer by inhibiting pyroptosis via the Hippo pathway
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - March 27, 2024 Category: Microbiology Authors: Ni WangLu ZhangXiao-Xu LengYi-Le XieZi-Ran KangLi-Cong ZhaoLin-Hong SongCheng-Bei ZhouJing-Yuan Fanga Division of Gastroenterology and Hepatology; Shanghai Institute of Digestive Disease; NHC Key Laboratory of Digestive Diseases; State Key Laboratory for Source Type: research
Membrane-anchoring selenophene viologens for antibacterial photodynamic therapy against periodontitis via restoring subgingival flora and alleviating inflammation
Biomaterials. 2024 Mar 21;307:122536. doi: 10.1016/j.biomaterials.2024.122536. Online ahead of print.ABSTRACTAntibacterial photodynamic therapy (aPDT) has emerged as a promising strategy for treating periodontitis. However, the weak binding of most photosensitizers to bacteria and the hypoxic environment of periodontal pockets severely hamper the therapeutic efficacy. Herein, two novel oxygen-independent photosensitizers are developed by introducing selenophene into viologens and modifying with hexane chains (HASeV) or quaternary ammonium chains (QASeV), which improve the adsorption to bacteria through anchoring to the neg...
Source: Biomaterials - March 24, 2024 Category: Materials Science Authors: Rui Ding Xu Liu Xiaodan Zhao Qi Sun Yilong Cheng Ang Li Dandan Pei Gang He Source Type: research
Membrane-anchoring selenophene viologens for antibacterial photodynamic therapy against periodontitis via restoring subgingival flora and alleviating inflammation
Biomaterials. 2024 Mar 21;307:122536. doi: 10.1016/j.biomaterials.2024.122536. Online ahead of print.ABSTRACTAntibacterial photodynamic therapy (aPDT) has emerged as a promising strategy for treating periodontitis. However, the weak binding of most photosensitizers to bacteria and the hypoxic environment of periodontal pockets severely hamper the therapeutic efficacy. Herein, two novel oxygen-independent photosensitizers are developed by introducing selenophene into viologens and modifying with hexane chains (HASeV) or quaternary ammonium chains (QASeV), which improve the adsorption to bacteria through anchoring to the neg...
Source: Biomaterials - March 24, 2024 Category: Materials Science Authors: Rui Ding Xu Liu Xiaodan Zhao Qi Sun Yilong Cheng Ang Li Dandan Pei Gang He Source Type: research
Gut Microbial Dysbiosis in the Pathogenesis of Leukemia: An Immune-based Perspective
A growing body of evidence points to the role of various human gut microbes in the genesis and progression of different cancers and hematological diseases including leukemia. This is carried out by both direct and indirect mechanisms [1]. For example, the bacterial species of Fusobacterium nucleatum directly binds to E-cadherin through its adhesin factor FadA (Fusobacterium adhesin A) thereby triggering the process of tumorigenesis in colorectal cancer [2]. Indirectly, the gut microbiota, with its constant provocation of the immune system, may lead into the development of cancer by creating a pro-inflammatory state within ...
Source: Experimental Hematology - March 23, 2024 Category: Hematology Authors: Mayuri Goswami, Purabi Deka Bose Tags: Review Source Type: research
Identification of temporal shifts of oral bacteria in bone regeneration following mandibular bone defect injury and therapeutic surgery in a porcine model
Mol Oral Microbiol. 2024 Mar 21. doi: 10.1111/omi.12460. Online ahead of print.ABSTRACTBACKGROUND: Considered the second largest and most diverse microbiome after the gut, the human oral ecosystem is complex with diverse and niche-specific microorganisms. Although evidence is growing for the importance of oral microbiome in supporting a healthy immune system and preventing local and systemic infections, the influence of craniomaxillofacial (CMF) trauma and routine reconstructive surgical treatments on community structure and function of oral resident microbes remains unknown. CMF injuries affect a large number of people, n...
Source: Cancer Control - March 21, 2024 Category: Cancer & Oncology Authors: Fatemeh Sanjar David T Silliman Ian J Johnson Zayer Htut Trent J Peacock Samira F Thompson Gregory R Dion Md A Nahid John F Decker Kai P Leung Source Type: research
A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche
Nature, Published online: 20 March 2024; doi:10.1038/s41586-024-07182-wA study reveals that Fusobacterium nucleatum subspecies animalis is bifurcated into two distinct clades, and shows that only one of these dominates the colorectal cancer niche, probably through increased colonization of the human gastrointestinal tract. (Source: Nature AOP)
Source: Nature AOP - March 20, 2024 Category: Research Authors: Martha Zepeda-Rivera Samuel S. Minot Heather Bouzek Hanrui Wu Aitor Blanco-M íguez Paolo Manghi Dakota S. Jones Kaitlyn D. LaCourse Ying Wu Elsa F. McMahon Soon-Nang Park Yun K. Lim Andrew G. Kempchinsky Amy D. Willis Sean L. Cotton Susan C. Yost Ewa Sic Source Type: research
Stratification of Fusobacterium nucleatum by local health status in the oral cavity defines its subspecies disease association
Cell Host Microbe. 2024 Mar 8:S1931-3128(24)00053-2. doi: 10.1016/j.chom.2024.02.010. Online ahead of print.ABSTRACTThe ubiquitous inflammophilic oral pathobiont Fusobacterium nucleatum (Fn) is widely recognized for its strong association with inflammatory dysbiotic diseases and cancer. Fn is subdivided into four subspecies, which are historically considered functionally interchangeable in the oral cavity. To test this assumption, we analyzed patient-matched dental plaque and odontogenic abscess clinical specimens and examined whether an inflammatory environment selects for/against particular Fn subspecies. Dental plaque h...
Source: Cell Host and Microbe - March 13, 2024 Category: Microbiology Authors: Madeline Krieger Yasser M AbdelRahman Dongseok Choi Elizabeth A Palmer Anna Yoo Sean McGuire Jens Kreth Justin Merritt Source Type: research
Stratification of Fusobacterium nucleatum by local health status in the oral cavity defines its subspecies disease association
Cell Host Microbe. 2024 Mar 8:S1931-3128(24)00053-2. doi: 10.1016/j.chom.2024.02.010. Online ahead of print.ABSTRACTThe ubiquitous inflammophilic oral pathobiont Fusobacterium nucleatum (Fn) is widely recognized for its strong association with inflammatory dysbiotic diseases and cancer. Fn is subdivided into four subspecies, which are historically considered functionally interchangeable in the oral cavity. To test this assumption, we analyzed patient-matched dental plaque and odontogenic abscess clinical specimens and examined whether an inflammatory environment selects for/against particular Fn subspecies. Dental plaque h...
Source: Cell Host and Microbe - March 13, 2024 Category: Microbiology Authors: Madeline Krieger Yasser M AbdelRahman Dongseok Choi Elizabeth A Palmer Anna Yoo Sean McGuire Jens Kreth Justin Merritt Source Type: research
Application of photoelectrochemical oxidation of wastewater used in the cooling tower water and its influence on microbial corrosion
DiscussionA metagenomics study revealed that bacteria present in the cooling tower water consists of 12% of Nitrospira genus and 22% of Fusobacterium genus. Conclusively, PEO serves as an effective method for treating wastewater, inhibiting microbial growth, degrading pollutants, and protecting metal from biocorrosion. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 13, 2024 Category: Microbiology Source Type: research
