Polymicrobial biofilms related to dental implant diseases: unravelling the critical role of extracellular biofilm matrix
Crit Rev Microbiol. 2022 May 18:1-21. doi: 10.1080/1040841X.2022.2062219. Online ahead of print.ABSTRACTBiofilms are complex tri-dimensional structures that encase microbial cells in an extracellular matrix comprising self-produced polymeric substances. The matrix rich in extracellular polymeric substance (EPS) contributes to the unique features of biofilm lifestyle and structure, enhancing microbial accretion, biofilm virulence, and antimicrobial resistance. The role of the EPS matrix of biofilms growing on biotic surfaces, especially dental surfaces, is largely unravelled. To date, there is a lack of a broad overview of ...
Source: Critical Reviews in Microbiology - May 18, 2022 Category: Microbiology Authors: Raphael C Costa Martinna Bertolini Barbara E Costa Oliveira Bruna E Nagay Caroline Dini Bruna Benso Marlise I Klein Valentim A R Bar āo Jo āo Gabriel S Souza Source Type: research

Polymicrobial biofilms related to dental implant diseases: unravelling the critical role of extracellular biofilm matrix
Crit Rev Microbiol. 2022 May 18:1-21. doi: 10.1080/1040841X.2022.2062219. Online ahead of print.ABSTRACTBiofilms are complex tri-dimensional structures that encase microbial cells in an extracellular matrix comprising self-produced polymeric substances. The matrix rich in extracellular polymeric substance (EPS) contributes to the unique features of biofilm lifestyle and structure, enhancing microbial accretion, biofilm virulence, and antimicrobial resistance. The role of the EPS matrix of biofilms growing on biotic surfaces, especially dental surfaces, is largely unravelled. To date, there is a lack of a broad overview of ...
Source: Critical Reviews in Microbiology - May 18, 2022 Category: Microbiology Authors: Raphael C Costa Martinna Bertolini Barbara E Costa Oliveira Bruna E Nagay Caroline Dini Bruna Benso Marlise I Klein Valentim A R Bar āo Jo āo Gabriel S Souza Source Type: research

Polymicrobial biofilms related to dental implant diseases: unravelling the critical role of extracellular biofilm matrix
Crit Rev Microbiol. 2022 May 18:1-21. doi: 10.1080/1040841X.2022.2062219. Online ahead of print.ABSTRACTBiofilms are complex tri-dimensional structures that encase microbial cells in an extracellular matrix comprising self-produced polymeric substances. The matrix rich in extracellular polymeric substance (EPS) contributes to the unique features of biofilm lifestyle and structure, enhancing microbial accretion, biofilm virulence, and antimicrobial resistance. The role of the EPS matrix of biofilms growing on biotic surfaces, especially dental surfaces, is largely unravelled. To date, there is a lack of a broad overview of ...
Source: Critical Reviews in Microbiology - May 18, 2022 Category: Microbiology Authors: Raphael C Costa Martinna Bertolini Barbara E Costa Oliveira Bruna E Nagay Caroline Dini Bruna Benso Marlise I Klein Valentim A R Bar āo Jo āo Gabriel S Souza Source Type: research

Probiotics: insights and new opportunities for < em > Clostridioides difficile < /em > intervention
Crit Rev Microbiol. 2022 May 15:1-21. doi: 10.1080/1040841X.2022.2072705. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) is a life-threatening disease caused by the Gram-positive, opportunistic intestinal pathogen C. difficile. Despite the availability of antimicrobial drugs to treat CDI, such as vancomycin, metronidazole, and fidaxomicin, recurrence of infection remains a significant clinical challenge. The use of live commensal microorganisms, or probiotics, is one of the most investigated non-antibiotic therapeutic options to balance gastrointestinal (GI) microbiota and subsequently tackle dysbio...
Source: Critical Reviews in Microbiology - May 16, 2022 Category: Microbiology Authors: Rusha Pal Ahmad I M Athamneh Riddhi Deshpande Jose A R Ramirez Kayode T Adu Pushpanathan Muthuirulan Shrikant Pawar Manuele Biazzo Yiorgos Apidianakis Ulrik Kraemer Sundekilde Cesar de la Fuente-Nunez Mark G Martens George P Tegos Mohamed N Seleem Source Type: research

Probiotics: insights and new opportunities for < em > Clostridioides difficile < /em > intervention
Crit Rev Microbiol. 2022 May 15:1-21. doi: 10.1080/1040841X.2022.2072705. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) is a life-threatening disease caused by the Gram-positive, opportunistic intestinal pathogen C. difficile. Despite the availability of antimicrobial drugs to treat CDI, such as vancomycin, metronidazole, and fidaxomicin, recurrence of infection remains a significant clinical challenge. The use of live commensal microorganisms, or probiotics, is one of the most investigated non-antibiotic therapeutic options to balance gastrointestinal (GI) microbiota and subsequently tackle dysbio...
Source: Critical Reviews in Microbiology - May 16, 2022 Category: Microbiology Authors: Rusha Pal Ahmad I M Athamneh Riddhi Deshpande Jose A R Ramirez Kayode T Adu Pushpanathan Muthuirulan Shrikant Pawar Manuele Biazzo Yiorgos Apidianakis Ulrik Kraemer Sundekilde Cesar de la Fuente-Nunez Mark G Martens George P Tegos Mohamed N Seleem Source Type: research

Probiotics: insights and new opportunities for < em > Clostridioides difficile < /em > intervention
Crit Rev Microbiol. 2022 May 15:1-21. doi: 10.1080/1040841X.2022.2072705. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) is a life-threatening disease caused by the Gram-positive, opportunistic intestinal pathogen C. difficile. Despite the availability of antimicrobial drugs to treat CDI, such as vancomycin, metronidazole, and fidaxomicin, recurrence of infection remains a significant clinical challenge. The use of live commensal microorganisms, or probiotics, is one of the most investigated non-antibiotic therapeutic options to balance gastrointestinal (GI) microbiota and subsequently tackle dysbio...
Source: Critical Reviews in Microbiology - May 16, 2022 Category: Microbiology Authors: Rusha Pal Ahmad I M Athamneh Riddhi Deshpande Jose A R Ramirez Kayode T Adu Pushpanathan Muthuirulan Shrikant Pawar Manuele Biazzo Yiorgos Apidianakis Ulrik Kraemer Sundekilde Cesar de la Fuente-Nunez Mark G Martens George P Tegos Mohamed N Seleem Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research

Leveraging big data bioinformatics approaches to extract knowledge from < em > Staphylococcus aureus < /em > public omics data
Crit Rev Microbiol. 2022 Apr 25:1-23. doi: 10.1080/1040841X.2022.2065905. Online ahead of print.ABSTRACTStaphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics techniques. Mining information from sequenced genomes and their expression data is an economic approach that alleviates wastage of resources and redundancy in experiments. The current review covers how big data bioinformatics has been used in the analysis of S. aureus from pub...
Source: Critical Reviews in Microbiology - April 25, 2022 Category: Microbiology Authors: Devika Subramanian Jeyakumar Natarajan Source Type: research