< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

< em > Sneathia < /em > : an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Crit Rev Microbiol. 2021 Apr 6:1-26. doi: 10.1080/1040841X.2021.1905606. Online ahead of print.ABSTRACTSneathia is an emerging pathogen implicated in adverse reproductive and perinatal outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes pathogenic following its ascension into the upper urogenital tract, amniotic fluid, placenta, and foetal membranes. The role of Sneathia in women's health and disease is generally underappreciated because the cultivation of these bacteria is limited by their complex nutritional requirements, slow growth patterns, and anaerobic nature. For this reason, mol...
Source: Critical Reviews in Microbiology - April 7, 2021 Category: Microbiology Authors: Kevin R Theis Violetta Florova Roberto Romero Andrei B Borisov Andrew D Winters Jose Galaz Nardhy Gomez-Lopez Source Type: research

Next-generation probiotics: a promising approach towards designing personalized medicine
Crit Rev Microbiol. 2021 Apr 6:1-20. doi: 10.1080/1040841X.2021.1902940. Online ahead of print.ABSTRACTSecond brain, forgotten organ, individual's identity card, and host's fingerprint are the few collective terms that are often used to describe the gut microbiome because of its variability, accountability, and its role in deciding the host's health. Also, the understanding of this host health-gut microbiota relationship can create an opportunity to control an individual's health by manipulating the gut microbiota composition. Several approaches like administration of probiotic, prebiotics, synbiotics, faecal microbiota tr...
Source: Critical Reviews in Microbiology - April 6, 2021 Category: Microbiology Authors: Tejinder Pal Singh Basavaprabhu Haranahalli Natraj Source Type: research

Rotavirus-related systemic diseases: clinical manifestation, evidence and pathogenesis
Crit Rev Microbiol. 2021 Apr 6:1-16. doi: 10.1080/1040841X.2021.1907738. Online ahead of print.ABSTRACTRotaviruses, double-stranded, non-enveloped RNA viruses, are a global health concern, associated with acute gastroenteritis and secretory-driven watery diarrhoea, especially in infants and young children. Conventionally, rotavirus is primarily viewed as a pathogen for intestinal enterocytes. This notion is challenged, however, by data from patients and animal models documenting extra-intestinal clinical manifestations and viral replication following rotavirus infection. In addition to acute gastroenteritis, rotavirus infe...
Source: Critical Reviews in Microbiology - April 6, 2021 Category: Microbiology Authors: Ziqin Dian Yi Sun Guiqian Zhang Ya Xu Xin Fan Xuemei Yang Qiuwei Pan Maikel Peppelenbosch Zhijiang Miao Source Type: research

Next-generation probiotics: a promising approach towards designing personalized medicine
Crit Rev Microbiol. 2021 Apr 6:1-20. doi: 10.1080/1040841X.2021.1902940. Online ahead of print.ABSTRACTSecond brain, forgotten organ, individual's identity card, and host's fingerprint are the few collective terms that are often used to describe the gut microbiome because of its variability, accountability, and its role in deciding the host's health. Also, the understanding of this host health-gut microbiota relationship can create an opportunity to control an individual's health by manipulating the gut microbiota composition. Several approaches like administration of probiotic, prebiotics, synbiotics, faecal microbiota tr...
Source: Critical Reviews in Microbiology - April 6, 2021 Category: Microbiology Authors: Tejinder Pal Singh Basavaprabhu Haranahalli Natraj Source Type: research

Rotavirus-related systemic diseases: clinical manifestation, evidence and pathogenesis
Crit Rev Microbiol. 2021 Apr 6:1-16. doi: 10.1080/1040841X.2021.1907738. Online ahead of print.ABSTRACTRotaviruses, double-stranded, non-enveloped RNA viruses, are a global health concern, associated with acute gastroenteritis and secretory-driven watery diarrhoea, especially in infants and young children. Conventionally, rotavirus is primarily viewed as a pathogen for intestinal enterocytes. This notion is challenged, however, by data from patients and animal models documenting extra-intestinal clinical manifestations and viral replication following rotavirus infection. In addition to acute gastroenteritis, rotavirus infe...
Source: Critical Reviews in Microbiology - April 6, 2021 Category: Microbiology Authors: Ziqin Dian Yi Sun Guiqian Zhang Ya Xu Xin Fan Xuemei Yang Qiuwei Pan Maikel Peppelenbosch Zhijiang Miao Source Type: research

Combatting intracellular pathogens using bacteriophage delivery
Crit Rev Microbiol. 2021 Apr 5:1-18. doi: 10.1080/1040841X.2021.1902266. Online ahead of print.ABSTRACTIntracellular pathogens reside in specialised compartments within the host cells restricting the access of antibiotics. Insufficient intracellular delivery of antibiotics along with several other resistance mechanisms weaken the efficacy of current therapies. An alternative to antibiotic therapy could be bacteriophage (phage) therapy. Although phage therapy has been in practice for a century against various bacterial infections, the efficacy of phages against intracellular bacteria is still being explored. In this review,...
Source: Critical Reviews in Microbiology - April 5, 2021 Category: Microbiology Authors: Avijit Goswami Pallavi Raj Sharma Rachit Agarwal Source Type: research

Combatting intracellular pathogens using bacteriophage delivery
Crit Rev Microbiol. 2021 Apr 5:1-18. doi: 10.1080/1040841X.2021.1902266. Online ahead of print.ABSTRACTIntracellular pathogens reside in specialised compartments within the host cells restricting the access of antibiotics. Insufficient intracellular delivery of antibiotics along with several other resistance mechanisms weaken the efficacy of current therapies. An alternative to antibiotic therapy could be bacteriophage (phage) therapy. Although phage therapy has been in practice for a century against various bacterial infections, the efficacy of phages against intracellular bacteria is still being explored. In this review,...
Source: Critical Reviews in Microbiology - April 5, 2021 Category: Microbiology Authors: Avijit Goswami Pallavi Raj Sharma Rachit Agarwal Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

The role of two-component regulatory systems in environmental sensing and virulence in < em > Salmonella < /em >
We describe important aspects of these systems, such as the stimuli and responses involved, the processes regulated, and their roles in virulence. We also dissect the genomic organization of histidine kinases and response regulators, as well as the input and output domains for each TCS. Lastly, we explore how these systems may be promising targets for the development of antivirulence therapeutics to combat antibiotic-resistant infections.PMID:33751923 | DOI:10.1080/1040841X.2021.1895067 (Source: Critical Reviews in Microbiology)
Source: Critical Reviews in Microbiology - March 22, 2021 Category: Microbiology Authors: Lucindo Cardoso de Pina Fernanda Stephens Hermes da Silva Teca Calcagno Galv ão Heidi Pauer Rosana Barreto Rocha Ferreira L Caetano M Antunes Source Type: research

Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Highlighting the use of micro and nanoparticles based-drug delivery systems for the treatment of < em > Helicobacter pylori < /em > infections
Crit Rev Microbiol. 2021 Mar 16:1-26. doi: 10.1080/1040841X.2021.1895721. Online ahead of print.ABSTRACTDue to the high adaptability of Helicobacter pylori and the low targeting specificity of the drugs normally used in pharmacological therapy, the strains are becoming increasingly resistant to these drugs, making it difficult to eradicate the infection. Thus, the search for new therapeutic approaches has been considered urgent. The incorporation of drugs in advanced drug delivery systems, such as nano and microparticles, would allow the improvement of the retention time in the stomach and the prolongation of drug release ...
Source: Critical Reviews in Microbiology - March 16, 2021 Category: Microbiology Authors: Maur ício Palmeira Chaves de Souza Bruna Almeida Furquim de Camargo Larissa Sp ósito Giovanna Capaldi Fortunato Gabriela Corr êa Carvalho Gabriel Davi Marena Andr éia Bagliotti Meneguin Ta ís Maria Bauab Marlus Chorilli Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Nisin resistance in Gram-positive bacteria and approaches to circumvent resistance for successful therapeutic use
Crit Rev Microbiol. 2021 Mar 9:1-10. doi: 10.1080/1040841X.2021.1893264. Online ahead of print.ABSTRACTAntibiotic resistance among bacterial pathogens is one of the most worrying problems in health systems today. To solve this problem, bacteriocins from lactic acid bacteria, especially nisin, have been proposed as an alternative for controlling multidrug-resistant bacteria. Bacteriocins are antimicrobial peptides that have activity mainly against Gram-positive strains. Nisin is one of the most studied bacteriocins and is already approved for use in food preservation. Nisin is still not approved for human clinical use, but ...
Source: Critical Reviews in Microbiology - March 10, 2021 Category: Microbiology Authors: Ana Andr éa Teixeira Barbosa Marcelo Rodrigues de Melo C ésar Matos Ribeiro da Silva Sona Jain Silvio Santana Dolabella Source Type: research

Polymicrobial interaction between < em > Lactobacillus < /em > and < em > Saccharomyces cerevisiae < /em > : coexistence-relevant mechanisms
Crit Rev Microbiol. 2021 Mar 4:1-11. doi: 10.1080/1040841X.2021.1893265. Online ahead of print.ABSTRACTThe coordination of single or multiple microorganisms are required for the manufacture of traditional fermented foods, improving the flavour and nutrition of the food materials. However, both the additional economic benefits and safety concerns have been raised by microbiotas in fermented products. Among the fermented products, Lactobacillus and Saccharomyces cerevisiae are one of the stable microbiotas, suggesting their interaction is mediated by coexistence-relevant mechanisms and prevent to be excluded by other microbi...
Source: Critical Reviews in Microbiology - March 5, 2021 Category: Microbiology Authors: Zhenbo Xu Zerong Lu Thanapop Soteyome Yanrui Ye Tengyi Huang Junyan Liu Janette M Harro Birthe V Kjellerup Brian M Peters Source Type: research

Polymicrobial interaction between < em > Lactobacillus < /em > and < em > Saccharomyces cerevisiae < /em > : coexistence-relevant mechanisms
Crit Rev Microbiol. 2021 Mar 4:1-11. doi: 10.1080/1040841X.2021.1893265. Online ahead of print.ABSTRACTThe coordination of single or multiple microorganisms are required for the manufacture of traditional fermented foods, improving the flavour and nutrition of the food materials. However, both the additional economic benefits and safety concerns have been raised by microbiotas in fermented products. Among the fermented products, Lactobacillus and Saccharomyces cerevisiae are one of the stable microbiotas, suggesting their interaction is mediated by coexistence-relevant mechanisms and prevent to be excluded by other microbi...
Source: Critical Reviews in Microbiology - March 5, 2021 Category: Microbiology Authors: Zhenbo Xu Zerong Lu Thanapop Soteyome Yanrui Ye Tengyi Huang Junyan Liu Janette M Harro Birthe V Kjellerup Brian M Peters Source Type: research

Polymicrobial interaction between < em > Lactobacillus < /em > and < em > Saccharomyces cerevisiae < /em > : coexistence-relevant mechanisms
Crit Rev Microbiol. 2021 Mar 4:1-11. doi: 10.1080/1040841X.2021.1893265. Online ahead of print.ABSTRACTThe coordination of single or multiple microorganisms are required for the manufacture of traditional fermented foods, improving the flavour and nutrition of the food materials. However, both the additional economic benefits and safety concerns have been raised by microbiotas in fermented products. Among the fermented products, Lactobacillus and Saccharomyces cerevisiae are one of the stable microbiotas, suggesting their interaction is mediated by coexistence-relevant mechanisms and prevent to be excluded by other microbi...
Source: Critical Reviews in Microbiology - March 5, 2021 Category: Microbiology Authors: Zhenbo Xu Zerong Lu Thanapop Soteyome Yanrui Ye Tengyi Huang Junyan Liu Janette M Harro Birthe V Kjellerup Brian M Peters Source Type: research

Polymicrobial interaction between < em > Lactobacillus < /em > and < em > Saccharomyces cerevisiae < /em > : coexistence-relevant mechanisms
Crit Rev Microbiol. 2021 Mar 4:1-11. doi: 10.1080/1040841X.2021.1893265. Online ahead of print.ABSTRACTThe coordination of single or multiple microorganisms are required for the manufacture of traditional fermented foods, improving the flavour and nutrition of the food materials. However, both the additional economic benefits and safety concerns have been raised by microbiotas in fermented products. Among the fermented products, Lactobacillus and Saccharomyces cerevisiae are one of the stable microbiotas, suggesting their interaction is mediated by coexistence-relevant mechanisms and prevent to be excluded by other microbi...
Source: Critical Reviews in Microbiology - March 5, 2021 Category: Microbiology Authors: Zhenbo Xu Zerong Lu Thanapop Soteyome Yanrui Ye Tengyi Huang Junyan Liu Janette M Harro Birthe V Kjellerup Brian M Peters Source Type: research

Polymicrobial interaction between < em > Lactobacillus < /em > and < em > Saccharomyces cerevisiae < /em > : coexistence-relevant mechanisms
Crit Rev Microbiol. 2021 Mar 4:1-11. doi: 10.1080/1040841X.2021.1893265. Online ahead of print.ABSTRACTThe coordination of single or multiple microorganisms are required for the manufacture of traditional fermented foods, improving the flavour and nutrition of the food materials. However, both the additional economic benefits and safety concerns have been raised by microbiotas in fermented products. Among the fermented products, Lactobacillus and Saccharomyces cerevisiae are one of the stable microbiotas, suggesting their interaction is mediated by coexistence-relevant mechanisms and prevent to be excluded by other microbi...
Source: Critical Reviews in Microbiology - March 5, 2021 Category: Microbiology Authors: Zhenbo Xu Zerong Lu Thanapop Soteyome Yanrui Ye Tengyi Huang Junyan Liu Janette M Harro Birthe V Kjellerup Brian M Peters Source Type: research

Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update
Crit Rev Microbiol. 2021 Mar 3:1-17. doi: 10.1080/1040841X.2021.1888867. Online ahead of print.ABSTRACTHalitosis or oral malodor is one of the most common reasons for the patients' visit to the dental clinic, ranking behind only dental caries and periodontitis. In the present times, where social and professional communications are becoming unavoidable, halitosis has become a concern of growing importance. Oral malodor mostly develops due to the putrefaction of substrates by the indigenous bacterial populations. Although culture-based studies have provided adequate information on halitosis, the high throughput omics technol...
Source: Critical Reviews in Microbiology - March 3, 2021 Category: Microbiology Authors: Lean Heong Foo Preethi Balan Li Mei Pang Marja L Laine Chaminda Jayampath Seneviratne Source Type: research

Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update
Crit Rev Microbiol. 2021 Mar 3:1-17. doi: 10.1080/1040841X.2021.1888867. Online ahead of print.ABSTRACTHalitosis or oral malodor is one of the most common reasons for the patients' visit to the dental clinic, ranking behind only dental caries and periodontitis. In the present times, where social and professional communications are becoming unavoidable, halitosis has become a concern of growing importance. Oral malodor mostly develops due to the putrefaction of substrates by the indigenous bacterial populations. Although culture-based studies have provided adequate information on halitosis, the high throughput omics technol...
Source: Critical Reviews in Microbiology - March 3, 2021 Category: Microbiology Authors: Lean Heong Foo Preethi Balan Li Mei Pang Marja L Laine Chaminda Jayampath Seneviratne Source Type: research

Community-wide changes reflecting bacterial interspecific interactions in multispecies biofilms
Crit Rev Microbiol. 2021 Mar 2:1-21. doi: 10.1080/1040841X.2021.1887079. Online ahead of print.ABSTRACTExistence of most bacterial species, in natural, industrial, and clinical settings in the form of surface-adhered communities or biofilms has been well acknowledged for decades. Research predominantly focusses on single-species biofilms as these are relatively easy to study. However, microbiologists are now interested in studying multispecies biofilms and revealing interspecific interactions in these communities because of the existence of a plethora of different bacterial species together in almost all natural settings. ...
Source: Critical Reviews in Microbiology - March 2, 2021 Category: Microbiology Authors: Faizan Ahmed Sadiq Mette Burm ølle Marc Heyndrickx Steve Flint Wenwei Lu Wei Chen Jianxin Zhao Hao Zhang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

< em > Candida albicans < /em > targets that potentially synergize with fluconazole
Crit Rev Microbiol. 2021 Feb 15:1-15. doi: 10.1080/1040841X.2021.1884641. Online ahead of print.ABSTRACTFluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Hui Lu Manjari Shrivastava Malcolm Whiteway Yuanying Jiang Source Type: research

Candida albicans targets that potentially synergize with fluconazole.
Abstract Fluconazole has characteristics that make it widely used in the clinical treatment of C. albicans infections. However, fluconazole has only a fungistatic activity in C. albicans, therefore, in the long-term treatment of C. albicans infection with fluconazole, C. albicans has the potential to acquire fluconazole resistance. A promising approach to increase fluconazole's efficacy is identifying potential targets of drugs that can enhance the antifungal effect of fluconazole, or even make the drug fungicidal. In this review, we systematically provide a global overview of potential targets of drugs synergisti...
Source: Critical Reviews in Microbiology - February 15, 2021 Category: Microbiology Authors: Lu H, Shrivastava M, Whiteway M, Jiang Y Tags: Crit Rev Microbiol Source Type: research