Clinical features and treatment outcomes of PD-1 inhibitor therapy in elderly patients ( ≥ 65 years) with advanced esophageal squamous cell carcinoma: a real-world study
ConclusionThe study demonstrated that individuals older than 65 years with locally advanced or metastatic ESCC have a survival benefit from the first-line treatment of PD-1 inhibitors combined therapy, with a manageable safety profile. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 11, 2024 Category: Cancer & Oncology Source Type: research
Machine Learning as a Diagnostic and Prognostic Tool for Predicting Thrombosis in Cancer Patients: A Systematic Review
This study was conducted per Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Databases Medline, EMBASE, Cochrane, and ClinicalTrials.gov, were searched from inception to September 15, 2023, for studies evaluating the use of ML models for the prediction of thrombosis in cancer patients. Search terms “machine learning,” “artificial intelligence,” “thrombosis,” and “cancer” were used. Studies that examined adult cancer patients using any ML model were included. Two independent reviewers conducted study selection and data extraction. Three hundred citations were screened, of which...
Source: Seminars in Thrombosis and Hemostasis - April 11, 2024 Category: Hematology Authors: El-Sherbini, Adham H. Coroneos, Stefania Zidan, Ali Othman, Maha Tags: Review Article Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
High LINC00626 expression promotes esophagogastric junction adenocarcinoma metastasis: the mediating role of the JAK1/STAT3/KHSRP axis
CONCLUSION: High LINC00626 expression promotes esophageal-gastric junction adenocarcinoma metastasis by activating the JAK1/STAT3/KHSRP signal axis.PMID:38597446 | DOI:10.12122/j.issn.1673-4254.2024.03.16 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: F Zhang L Fan X Kang H Wei L Li Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
High LINC00626 expression promotes esophagogastric junction adenocarcinoma metastasis: the mediating role of the JAK1/STAT3/KHSRP axis
CONCLUSION: High LINC00626 expression promotes esophageal-gastric junction adenocarcinoma metastasis by activating the JAK1/STAT3/KHSRP signal axis.PMID:38597446 | PMC:PMC11006707 | DOI:10.12122/j.issn.1673-4254.2024.03.16 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: F Zhang L Fan X Kang H Wei L Li Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
High LINC00626 expression promotes esophagogastric junction adenocarcinoma metastasis: the mediating role of the JAK1/STAT3/KHSRP axis
CONCLUSION: High LINC00626 expression promotes esophageal-gastric junction adenocarcinoma metastasis by activating the JAK1/STAT3/KHSRP signal axis.PMID:38597446 | PMC:PMC11006707 | DOI:10.12122/j.issn.1673-4254.2024.03.16 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: F Zhang L Fan X Kang H Wei L Li Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
Nomograms and prognosis for superficial esophageal squamous cell carcinoma
World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated ...
Source: World Journal of Gastroenterology : WJG - April 10, 2024 Category: Gastroenterology Authors: Hong Tao Lin Ahmed Abdelbaki Somashekar G Krishna Source Type: research
High LINC00626 expression promotes esophagogastric junction adenocarcinoma metastasis: the mediating role of the JAK1/STAT3/KHSRP axis
CONCLUSION: High LINC00626 expression promotes esophageal-gastric junction adenocarcinoma metastasis by activating the JAK1/STAT3/KHSRP signal axis.PMID:38597446 | PMC:PMC11006707 | DOI:10.12122/j.issn.1673-4254.2024.03.16 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: F Zhang L Fan X Kang H Wei L Li Source Type: research
High LINC00626 expression promotes esophagogastric junction adenocarcinoma metastasis: the mediating role of the JAK1/STAT3/KHSRP axis
CONCLUSION: High LINC00626 expression promotes esophageal-gastric junction adenocarcinoma metastasis by activating the JAK1/STAT3/KHSRP signal axis.PMID:38597446 | PMC:PMC11006707 | DOI:10.12122/j.issn.1673-4254.2024.03.16 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: F Zhang L Fan X Kang H Wei L Li Source Type: research
