Nomograms and prognosis for superficial esophageal squamous cell carcinoma

World J Gastroenterol. 2024 Mar 14;30(10):1291-1294. doi: 10.3748/wjg.v30.i10.1291.ABSTRACTIn recent years, endoscopic resection, particularly endoscopic submucosal dissection, has become increasingly popular in treating non-metastatic superficial esophageal squamous cell carcinoma (ESCC). In this evolving paradigm, it is crucial to identify factors that predict higher rates of lymphatic invasion and poorer outcomes. Larger tumor size, deeper invasion, poorer differentiation, more infiltrative growth patterns (INF-c), higher-grade tumor budding, positive lymphovascular invasion, and certain biomarkers have been associated with lymph node metastasis and increased morbidity through retrospective reviews, leading to the construction of comprehensive nomograms for outcome prediction. If validated by future prospective studies, these nomograms would prove highly applicable in guiding the selection of treatment for superficial ESCC.PMID:38596490 | PMC:PMC11000082 | DOI:10.3748/wjg.v30.i10.1291
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research