Design of low-cost natural casein biopolymer based adsorbent for efficient adsorption of multiple anionic dyes and diclofenac sodium from aqueous solutions
Chemosphere. 2024 Feb 27:141571. doi: 10.1016/j.chemosphere.2024.141571. Online ahead of print.ABSTRACTThe treatment of various organic pollutants from industrial wastewater using bio-based materials has gained significant attention owing to their excellent properties such as low-cost, eco-friendly, non-toxic, and biodegradability. In this perspective, casein (Cn), a protein-based biopolymer, was extracted from the cow milk as a low-cost adsorbent, and the adsorption performances were determined for the pristine Cn. The adsorbent was employed for the removal of two different classes of targeted pollutant anionic dyes such ...
Source: Chemosphere - February 29, 2024 Category: Chemistry Authors: Vinayak Hegde U T Uthappa PadmajaV Mane Seong Min Ji Maduru Suneetha Ben Wang Tariq Altalhi T M Subrahmanya Mahaveer D Kurkuri Source Type: research
Design of low-cost natural casein biopolymer based adsorbent for efficient adsorption of multiple anionic dyes and diclofenac sodium from aqueous solutions
Chemosphere. 2024 Feb 27:141571. doi: 10.1016/j.chemosphere.2024.141571. Online ahead of print.ABSTRACTThe treatment of various organic pollutants from industrial wastewater using bio-based materials has gained significant attention owing to their excellent properties such as low-cost, eco-friendly, non-toxic, and biodegradability. In this perspective, casein (Cn), a protein-based biopolymer, was extracted from the cow milk as a low-cost adsorbent, and the adsorption performances were determined for the pristine Cn. The adsorbent was employed for the removal of two different classes of targeted pollutant anionic dyes such ...
Source: Chemosphere - February 29, 2024 Category: Chemistry Authors: Vinayak Hegde U T Uthappa PadmajaV Mane Seong Min Ji Maduru Suneetha Ben Wang Tariq Altalhi T M Subrahmanya Mahaveer D Kurkuri Source Type: research
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes - detailed studies on CYP3A inhibitors
In conclusion, we identified several glucuronide metabolites with CYP inhibitory properties. Based on detailed experiments, the inactivation of CYP3A by carvedilol may cause clinically significant drug-drug interactions.PMID:38423227 | DOI:10.1016/j.ejps.2024.106735 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - February 29, 2024 Category: Drugs & Pharmacology Authors: Helin ä Kahma Marie-No ëlle Paludetto Mikko Neuvonen Mika Kurkela Anne M Filppula Mikko Niemi Janne T Backman Source Type: research
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes - detailed studies on CYP3A inhibitors
In conclusion, we identified several glucuronide metabolites with CYP inhibitory properties. Based on detailed experiments, the inactivation of CYP3A by carvedilol may cause clinically significant drug-drug interactions.PMID:38423227 | DOI:10.1016/j.ejps.2024.106735 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - February 29, 2024 Category: Drugs & Pharmacology Authors: Helin ä Kahma Marie-No ëlle Paludetto Mikko Neuvonen Mika Kurkela Anne M Filppula Mikko Niemi Janne T Backman Source Type: research
The Protective Effects of Vitamin B Complex on Diclofenac Sodium-Induced Nephrotoxicity: The Role of NOX4/RhoA/ROCK
In conclusion, vitamin B complex administration could be a renoprotective approach during treatment with DIC via, at least in part, suppressing the NOX4/RhoA/ROCK pathway. (Source: Inflammation)
Source: Inflammation - February 28, 2024 Category: Allergy & Immunology Source Type: research
Topical Diclofenac for Prevention of Capecitabine-Associated Hand-Foot Syndrome: A Double-Blind Randomized Controlled Trial
CONCLUSION: Topical diclofenac prevented HFS in patients receiving capecitabine. This trial supports the use of topical diclofenac to prevent capecitabine-associated HFS.PMID:38412399 | DOI:10.1200/JCO.23.01730 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - February 27, 2024 Category: Cancer & Oncology Authors: Akhil Santhosh Atul Sharma Sameer Bakhshi Akash Kumar Vinod Sharma Prabhat Singh Malik Raja Pramanik Ajay Gogia Chandra Prakash Prasad Tushar Sehgal Sneha Gund Arundhathi Dev Winson Y Cheung R M Pandey Saran Kumar Ishaan Gupta Atul Batra D-TORCH Trial Inv Source Type: research
Topical Diclofenac for Prevention of Capecitabine-Associated Hand-Foot Syndrome: A Double-Blind Randomized Controlled Trial
CONCLUSION: Topical diclofenac prevented HFS in patients receiving capecitabine. This trial supports the use of topical diclofenac to prevent capecitabine-associated HFS.PMID:38412399 | DOI:10.1200/JCO.23.01730 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - February 27, 2024 Category: Cancer & Oncology Authors: Akhil Santhosh Atul Sharma Sameer Bakhshi Akash Kumar Vinod Sharma Prabhat Singh Malik Raja Pramanik Ajay Gogia Chandra Prakash Prasad Tushar Sehgal Sneha Gund Arundhathi Dev Winson Y Cheung R M Pandey Saran Kumar Ishaan Gupta Atul Batra D-TORCH Trial Inv Source Type: research
The mechanism and reaction kinetics of visible light active bismuth oxide deposited on titanium vanadium oxide for aqueous diclofenac photocatalysis
Environ Sci Pollut Res Int. 2024 Feb 28. doi: 10.1007/s11356-024-32477-w. Online ahead of print.ABSTRACTNon-uniform, non-spherical bismuth oxide deposited on titanium vanadium oxide (3%-BVT1) was successfully synthesized via co-precipitation method and assessed for visible light degradation of aqueous diclofenac. The synthesized photocatalysts were characterized using X-ray diffraction, diffuse reflectance spectroscopy, X-ray photoelectron spectroscopy, scanning electron microscopy, and high-resolution transmission electron microscopy. Up to 80.7% diclofenac degradation was observed with a significant increment in reaction...
Source: Environmental Science and Pollution Research International - February 27, 2024 Category: Environmental Health Authors: Mehmooda Bibi Jamshaid Rashid Asima Siddiqa Ming Xu Source Type: research
Topical Diclofenac for Prevention of Capecitabine-Associated Hand-Foot Syndrome: A Double-Blind Randomized Controlled Trial
CONCLUSION: Topical diclofenac prevented HFS in patients receiving capecitabine. This trial supports the use of topical diclofenac to prevent capecitabine-associated HFS.PMID:38412399 | DOI:10.1200/JCO.23.01730 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - February 27, 2024 Category: Cancer & Oncology Authors: Akhil Santhosh Atul Sharma Sameer Bakhshi Akash Kumar Vinod Sharma Prabhat Singh Malik Raja Pramanik Ajay Gogia Chandra Prakash Prasad Tushar Sehgal Sneha Gund Arundhathi Dev Winson Y Cheung R M Pandey Saran Kumar Ishaan Gupta Atul Batra D-TORCH Trial Inv Source Type: research
Topical Diclofenac for Prevention of Capecitabine-Associated Hand-Foot Syndrome: A Double-Blind Randomized Controlled Trial
CONCLUSION: Topical diclofenac prevented HFS in patients receiving capecitabine. This trial supports the use of topical diclofenac to prevent capecitabine-associated HFS.PMID:38412399 | DOI:10.1200/JCO.23.01730 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - February 27, 2024 Category: Cancer & Oncology Authors: Akhil Santhosh Atul Sharma Sameer Bakhshi Akash Kumar Vinod Sharma Prabhat Singh Malik Raja Pramanik Ajay Gogia Chandra Prakash Prasad Tushar Sehgal Sneha Gund Arundhathi Dev Winson Y Cheung R M Pandey Saran Kumar Ishaan Gupta Atul Batra D-TORCH Trial Inv Source Type: research
Evaluation of diclofenac utilization patterns before and after digital risk minimization intervention in outpatient settings in Montenegro
ConclusionsAlthough a significant decrease in diclofenac prescription in both cohorts occurred, diclofenac is still prescribed, even in diagnoses contraindicated for its use. Further improvements of existing tools and the creation of new ones are necessary for minimization of cardiovascular and other risks related to diclofenac. (Source: Drugs and Therapy Perspectives)
Source: Drugs and Therapy Perspectives - February 24, 2024 Category: Drugs & Pharmacology Source Type: research
Adsorption of anti-inflammatory and analgesic drugs traces in water on clay minerals
Chemosphere. 2024 Feb 20:141469. doi: 10.1016/j.chemosphere.2024.141469. Online ahead of print.ABSTRACTThe aim of this study was to assess the adsorption of four non-steroidal anti-inflammatory drugs (NSAIDs), namely Paracetamol (PRC), Diclofenac (DIC), Ibuprofen (IBU), and Ketoprofen (KET), using both batch and continuous experiments with clay. Various analytical techniques, including XRD, FTIR, SEM coupled to EDX, and Zeta potential, were employed to characterize both raw and calcined clay. XRD and FTIR analyses confirmed the kaolinite nature of the clay. SEM data revealed a lamellar structure formed in the clay after ca...
Source: Chemosphere - February 22, 2024 Category: Chemistry Authors: Fatma Mansouri Khawla Chouchene Ahmed Wali Jerome Labille Nicolas Roche Mohamed Ksibi Source Type: research
Comparing different versions of the Yoon-Nelson model in describing organic micropollutant adsorption within fixed bed adsorbers
This study aims to augment its modeling efficacy through two proposed refinements found in the literature: a logarithmic transformation and the incorporation of steric hindrance effects. We systematically evaluated the original Yoon-Nelson model alongside the modified versions, using breakthrough data associated with micropollutant adsorption on solid materials. Three distinct cases were scrutinized: (1) caffeine adsorption on activated carbon; (2) tetracycline adsorption on hierarchical porous carbon; and (3) diclofenac adsorption on organoclay. While all three models demonstrated comparable performance with highly symmet...
Source: Environmental Science and Pollution Research International - February 22, 2024 Category: Environmental Health Authors: Khim Hoong Chu Mohd Ali Hashim Source Type: research
Adsorption of anti-inflammatory and analgesic drugs traces in water on clay minerals
Chemosphere. 2024 Feb 20:141469. doi: 10.1016/j.chemosphere.2024.141469. Online ahead of print.ABSTRACTThe aim of this study was to assess the adsorption of four non-steroidal anti-inflammatory drugs (NSAIDs), namely Paracetamol (PRC), Diclofenac (DIC), Ibuprofen (IBU), and Ketoprofen (KET), using both batch and continuous experiments with clay. Various analytical techniques, including XRD, FTIR, SEM coupled to EDX, and Zeta potential, were employed to characterize both raw and calcined clay. XRD and FTIR analyses confirmed the kaolinite nature of the clay. SEM data revealed a lamellar structure formed in the clay after ca...
Source: Chemosphere - February 22, 2024 Category: Chemistry Authors: Fatma Mansouri Khawla Chouchene Ahmed Wali Jerome Labille Nicolas Roche Mohamed Ksibi Source Type: research
