A Novel Approach of Polyvinyl Alcohol/Acrylic Acid Based Hydrogels for Controlled Delivery of Diclofenac Sodium
CONCLUSION: The results indicated that prepared PVA/AA hydrogels can be used as an alternative approach for the controlled delivery of diclofenac sodium.PMID:38623980 | DOI:10.2174/0113892010296120240327055943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 16, 2024 Category: Biotechnology Authors: Muhammad Suhail Syed Faisal Badshah I-Hui Chiu Arif Ullah Arshad Khan Hamid Ullah Noorah Saleh Al-Sowayan Ming-Jun Tsai Pao-Chu Wu Source Type: research
A Novel Approach of Polyvinyl Alcohol/Acrylic Acid Based Hydrogels for Controlled Delivery of Diclofenac Sodium
CONCLUSION: The results indicated that prepared PVA/AA hydrogels can be used as an alternative approach for the controlled delivery of diclofenac sodium.PMID:38623980 | DOI:10.2174/0113892010296120240327055943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 16, 2024 Category: Biotechnology Authors: Muhammad Suhail Syed Faisal Badshah I-Hui Chiu Arif Ullah Arshad Khan Hamid Ullah Noorah Saleh Al-Sowayan Ming-Jun Tsai Pao-Chu Wu Source Type: research
A Novel Approach of Polyvinyl Alcohol/Acrylic Acid Based Hydrogels for Controlled Delivery of Diclofenac Sodium
CONCLUSION: The results indicated that prepared PVA/AA hydrogels can be used as an alternative approach for the controlled delivery of diclofenac sodium.PMID:38623980 | DOI:10.2174/0113892010296120240327055943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 16, 2024 Category: Biotechnology Authors: Muhammad Suhail Syed Faisal Badshah I-Hui Chiu Arif Ullah Arshad Khan Hamid Ullah Noorah Saleh Al-Sowayan Ming-Jun Tsai Pao-Chu Wu Source Type: research
Anaerobic co-metabolic biodegradation of pharmaceuticals and personal care products driven by glycerol fermentation
This study showed evidence that glycerol co-fermentation can exert a synergistic effect on the PPCPs removal during anaerobic digestion mediated by heterotrophic co-metabolism.PMID:38621493 | DOI:10.1016/j.chemosphere.2024.142006 (Source: Chemosphere)
Source: Chemosphere - April 15, 2024 Category: Chemistry Authors: Rodrigo B Carneiro Gisele M Gomes Franciele P Camargo Marcelo Zaiat Álvaro J Santos-Neto Source Type: research
Anaerobic co-metabolic biodegradation of pharmaceuticals and personal care products driven by glycerol fermentation
This study showed evidence that glycerol co-fermentation can exert a synergistic effect on the PPCPs removal during anaerobic digestion mediated by heterotrophic co-metabolism.PMID:38621493 | DOI:10.1016/j.chemosphere.2024.142006 (Source: Chemosphere)
Source: Chemosphere - April 15, 2024 Category: Chemistry Authors: Rodrigo B Carneiro Gisele M Gomes Franciele P Camargo Marcelo Zaiat Álvaro J Santos-Neto Source Type: research
Physicochemical, structural and biological characterisation of poly(3-hydroxyoctanoate) supplemented with diclofenac acid conjugates - Harnessing the potential in the construction of materials for skin regeneration processes
This study involved creating oligomeric conjugates of 3-hydroxy fatty acids and diclofenac, named Dic-oligo(3HAs). Advanced NMR techniques confirmed no free diclofenac in the mix. We tested diclofenac release under conditions resembling healthy and chronic wound skin. These oligomers were used to make P(3HO) blends, forming patches for drug delivery. Their preparation used the solvent casting/porogen leaching (SCPL) method. The patches' properties like porosity, roughness, and wettability were thoroughly analysed. Antimicrobial assays showed that Dic-oligo(3HAs) exhibited antimicrobial activity against reference (S. aureus...
Source: International Journal of Biological Macromolecules - April 13, 2024 Category: Biochemistry Authors: Katarzyna Hara źna Annabelle T Fricker Rafa ł Konefał Aneta Medaj Ma łgorzata Zimowsk Bartosz Leszczy ński Andrzej Wr óbel Andrzej J Bojarski Ipsita Roy Maciej Guzik Source Type: research
Optimized Design of Quaternary Amino-Functionalized Chitosan Fibers for Ultra-High Diclofenac Adsorption from Wastewater
Chemosphere. 2024 Apr 10:141970. doi: 10.1016/j.chemosphere.2024.141970. Online ahead of print.ABSTRACTThe extraction of non-steroidal anti-inflammatory drugs (NSAIDs) from water bodies is imperative due to the potential harm to humans and the ecosystem caused by NSAID-contaminated water. Quaternary amino-functionalized epichlorohydrin cross-linked chitosan fibers (QECFs), an economical and eco-friendly adsorbent, were successfully prepared using a simple and gentle method for efficient diclofenac (DCF) adsorption. Additionally, the optimized factors for the preparation of QECFs included epichlorohydrin concentration, pH, ...
Source: Chemosphere - April 12, 2024 Category: Chemistry Authors: Xiaoyu Lin Myung-Hee Song Wenhao Li Wei Wei Xiaohui Wu Juan Mao Yeoung-Sang Yun Source Type: research
Environmental risk assessment of selected pharmaceuticals in hospital wastewater in nothern vietnam
This study investigated the occurrence of selected pharmaceuticals in influent and effluent of wastewater treatment plants of 12 hospitals in Hanoi and 3 northern cities of Vietnam during dry and rainy seasons. In addition, environmental risk of pharmaceuticals in both hospital influents and effluents were evaluated based on risk quotients (RQs). Nine selected pharmaceutical compounds including sulfamethoxazole (SMX), naproxen (NPX), diclofenac (DCF), ibuprofen (IBU), acetaminophen (ACT), carbamazepine (CBM), iopromide (IOP), atenolol (ATN), and caffeine (CAF) were frequently detected in most influent and effluent wastewat...
Source: Chemosphere - April 12, 2024 Category: Chemistry Authors: Anh T P Hoang Manh Cuong Do Kyoung-Woong Kim Source Type: research
Synthesis of recyclable and light-weight graphene oxide/chitosan/genipin sponges for the adsorption of diclofenac, triclosan, and microplastics
Chemosphere. 2024 Apr 9:141956. doi: 10.1016/j.chemosphere.2024.141956. Online ahead of print.ABSTRACTEmerging micropollutants, such as pharmaceuticals and microplastics (MPs), have become a pressing water environmental concern. The aim of this study is to synthesize chitosan sponges using graphene oxide (GO) and genipin (GP) for the removal of pharmaceuticals (diclofenac (DCF) and triclosan (TCS)) and MPs, verify their adsorption mechanisms, evaluate the effects of temperature, pH, and salinity on their adsorption capacities, and determine their reusability. The GO5/CS/GP sponge exhibited a macroporous nature (porosity = ...
Source: Chemosphere - April 11, 2024 Category: Chemistry Authors: Mingi Ko Taesoon Jang Soyeong Yoon Jooyoung Lee Jin-Hyuk Choi Jae-Woo Choi Jeong-Ann Park Source Type: research
Synthesis of recyclable and light-weight graphene oxide/chitosan/genipin sponges for the adsorption of diclofenac, triclosan, and microplastics
Chemosphere. 2024 Apr 9:141956. doi: 10.1016/j.chemosphere.2024.141956. Online ahead of print.ABSTRACTEmerging micropollutants, such as pharmaceuticals and microplastics (MPs), have become a pressing water environmental concern. The aim of this study is to synthesize chitosan sponges using graphene oxide (GO) and genipin (GP) for the removal of pharmaceuticals (diclofenac (DCF) and triclosan (TCS)) and MPs, verify their adsorption mechanisms, evaluate the effects of temperature, pH, and salinity on their adsorption capacities, and determine their reusability. The GO5/CS/GP sponge exhibited a macroporous nature (porosity = ...
Source: Chemosphere - April 11, 2024 Category: Chemistry Authors: Mingi Ko Taesoon Jang Soyeong Yoon Jooyoung Lee Jin-Hyuk Choi Jae-Woo Choi Jeong-Ann Park Source Type: research
Synthesis of recyclable and light-weight graphene oxide/chitosan/genipin sponges for the adsorption of diclofenac, triclosan, and microplastics
Chemosphere. 2024 Apr 9:141956. doi: 10.1016/j.chemosphere.2024.141956. Online ahead of print.ABSTRACTEmerging micropollutants, such as pharmaceuticals and microplastics (MPs), have become a pressing water environmental concern. The aim of this study is to synthesize chitosan sponges using graphene oxide (GO) and genipin (GP) for the removal of pharmaceuticals (diclofenac (DCF) and triclosan (TCS)) and MPs, verify their adsorption mechanisms, evaluate the effects of temperature, pH, and salinity on their adsorption capacities, and determine their reusability. The GO5/CS/GP sponge exhibited a macroporous nature (porosity = ...
Source: Chemosphere - April 11, 2024 Category: Chemistry Authors: Mingi Ko Taesoon Jang Soyeong Yoon Jooyoung Lee Jin-Hyuk Choi Jae-Woo Choi Jeong-Ann Park Source Type: research
Recent Advancements in Refashioning of NSAIDs and their Derivatives as Anticancer Candidates
Curr Pharm Des. 2024 Apr 5. doi: 10.2174/0113816128304230240327044201. Online ahead of print.ABSTRACTInflammation is critical to the formation and development of tumors and is closely associated with cancer. Therefore, addressing inflammation and the mediators that contribute to the inflammatory process may be a useful strategy for both cancer prevention and treatment. Tumor predisposition can be attributed to inflammation. It has been demonstrated that NSAIDs can modify the tumor microenvironment by enhancing apoptosis and chemosensitivity and reducing cell migration. There has been a recent rise in interest in drug repos...
Source: Current Pharmaceutical Design - April 8, 2024 Category: Drugs & Pharmacology Authors: Asmaa E Kassab Ehab M Gedawy Source Type: research
Recent Advancements in Refashioning of NSAIDs and their Derivatives as Anticancer Candidates
Curr Pharm Des. 2024 Apr 5. doi: 10.2174/0113816128304230240327044201. Online ahead of print.ABSTRACTInflammation is critical to the formation and development of tumors and is closely associated with cancer. Therefore, addressing inflammation and the mediators that contribute to the inflammatory process may be a useful strategy for both cancer prevention and treatment. Tumor predisposition can be attributed to inflammation. It has been demonstrated that NSAIDs can modify the tumor microenvironment by enhancing apoptosis and chemosensitivity and reducing cell migration. There has been a recent rise in interest in drug repos...
Source: Current Pharmaceutical Design - April 8, 2024 Category: Drugs & Pharmacology Authors: Asmaa E Kassab Ehab M Gedawy Source Type: research
Recent Advancements in Refashioning of NSAIDs and their Derivatives as Anticancer Candidates
Curr Pharm Des. 2024 Apr 5. doi: 10.2174/0113816128304230240327044201. Online ahead of print.ABSTRACTInflammation is critical to the formation and development of tumors and is closely associated with cancer. Therefore, addressing inflammation and the mediators that contribute to the inflammatory process may be a useful strategy for both cancer prevention and treatment. Tumor predisposition can be attributed to inflammation. It has been demonstrated that NSAIDs can modify the tumor microenvironment by enhancing apoptosis and chemosensitivity and reducing cell migration. There has been a recent rise in interest in drug repos...
Source: Current Pharmaceutical Design - April 8, 2024 Category: Drugs & Pharmacology Authors: Asmaa E Kassab Ehab M Gedawy Source Type: research
Recent Advancements in Refashioning of NSAIDs and their Derivatives as Anticancer Candidates
Curr Pharm Des. 2024 Apr 5. doi: 10.2174/0113816128304230240327044201. Online ahead of print.ABSTRACTInflammation is critical to the formation and development of tumors and is closely associated with cancer. Therefore, addressing inflammation and the mediators that contribute to the inflammatory process may be a useful strategy for both cancer prevention and treatment. Tumor predisposition can be attributed to inflammation. It has been demonstrated that NSAIDs can modify the tumor microenvironment by enhancing apoptosis and chemosensitivity and reducing cell migration. There has been a recent rise in interest in drug repos...
Source: Current Pharmaceutical Design - April 8, 2024 Category: Drugs & Pharmacology Authors: Asmaa E Kassab Ehab M Gedawy Source Type: research
