Removal of diclofenac sodium from aqueous solution using different ionic liquids functionalized tragacanth gum hydrogel prepared by radiation technique
In this study, different alkyl substituted ionic liquids (1-alkyl -3-vinyl- imidazolium bromide [CnVIm]Br, n = 4, 6, 8, 10, 12) functionalized tragacanth gum (TG-CnBr) are prepared by radiation induced grafting and crosslinking polymerization. The adsorption behaviors of ionic liquids functionalized tragacanth gum for diclofenac sodium from aqueous solutions are examined. The adsorption capacity of TG-CnBr for diclofenac sodium increases with the increasing of alkyl chain length of the imidazolium cation and the hydrophobicity of the hydrogels. The maximum adsorption capacity by TG-C12Br for diclofenac sodium at 30, 40 and...
Source: International Journal of Biological Macromolecules - March 10, 2024 Category: Biochemistry Authors: Jifu Du Ke Xu Xin Yang Zhen Dong Long Zhao Source Type: research
Synthesis of sustainable mesoporous sulfur-doped biobased carbon with superior performance sodium diclofenac removal: Kinetic, equilibrium, thermodynamic and mechanism
Environ Res. 2024 Mar 8:118595. doi: 10.1016/j.envres.2024.118595. Online ahead of print.ABSTRACTOver the last years, the strategy of employing inevitable organic waste and residue streams to produce valuable and greener materials for a wide range of applications has been proven an efficient and suitable approach. In this research, sulphur-doped porous biochar was produced through a single-step pyrolysis of birch waste tree in the presence of zinc chloride as chemical activator. The sulfur doping process led to a remarkable impact on the biochar structure. Moreover, it was shown that sulfur doping also had an important imp...
Source: Environmental Research - March 10, 2024 Category: Environmental Health Authors: Glaydson S Dos Reis Alejandro Grimm Denise Alves Fungaro Tao Hu Irineu A S de Brum Eder C Lima Mu Naushad Guilherme L Dotto Ulla Lassi Source Type: research
Removal of diclofenac sodium from aqueous solution using different ionic liquids functionalized tragacanth gum hydrogel prepared by radiation technique
In this study, different alkyl substituted ionic liquids (1-alkyl -3-vinyl- imidazolium bromide [CnVIm]Br, n = 4, 6, 8, 10, 12) functionalized tragacanth gum (TG-CnBr) are prepared by radiation induced grafting and crosslinking polymerization. The adsorption behaviors of ionic liquids functionalized tragacanth gum for diclofenac sodium from aqueous solutions are examined. The adsorption capacity of TG-CnBr for diclofenac sodium increases with the increasing of alkyl chain length of the imidazolium cation and the hydrophobicity of the hydrogels. The maximum adsorption capacity by TG-C12Br for diclofenac sodium at 30, 40 and...
Source: International Journal of Biological Macromolecules - March 10, 2024 Category: Biochemistry Authors: Jifu Du Ke Xu Xin Yang Zhen Dong Long Zhao Source Type: research
Drug-induced liver injury (DILI) ascribed to non-steroidal anti-inflammatory drugs (NSAIDs) in the USA-Update with genetic correlations
CONCLUSIONS: Despite prevalent use, NSAID-DILI is infrequent in the United States. Diclofenac is the most commonly implicated, and adherence to warnings of risk and close observation are recommended. The increased frequency of HLA-B*35:03 and DRB1*04:03, driven by diclofenac, suggests the importance of immune-mediated responses.PMID:38451034 | DOI:10.1111/liv.15892 (Source: Cancer Control)
Source: Cancer Control - March 7, 2024 Category: Cancer & Oncology Authors: Herbert L Bonkovsky Marwan Ghabril Paola Nicoletti Andrew Dellinger Robert J Fontana Huiman Barnhart Jiezhun Gu Ann K Daly Guruprasad P Aithal Elizabeth J Phillips David E Kleiner US DILIN Investigators Source Type: research
β-keto amyrin isolated from Cryptostegia grandiflora R. br. inhibits inflammation caused by Daboia russellii viper venom: Direct binding of β-keto amyrin to phospholipase A < sub > 2 < /sub >
Toxicon. 2024 Mar 4:107679. doi: 10.1016/j.toxicon.2024.107679. Online ahead of print.ABSTRACTThe search for mechanism-based anti-inflammatory therapies is of fundamental importance to avoid undesired off-target effects. Phospholipase A2 (PLA2) activity is a potential molecular target for anti-inflammatory drugs because it fuels arachidonic acid needed to synthesize inflammation mediators, such as prostaglandins. Herein, we aim to investigate the molecular mechanism by which β-keto amyrin isolated from a methanolic extract of Cryptostegia grandiflora R. Br. Leaves can inhibit inflammation caused by Daboia russellii viper ...
Source: Toxicon - March 6, 2024 Category: Toxicology Authors: K H Santhosh V Krishna K Kemparaju H Manjunatha R Shashi Kumar Mukherjee Arnab S E Gomez Mejiba D C Ramirez B S Ravindranath Source Type: research
β-keto amyrin isolated from Cryptostegia grandiflora R. br. inhibits inflammation caused by Daboia russellii viper venom: Direct binding of β-keto amyrin to phospholipase A < sub > 2 < /sub >
Toxicon. 2024 Mar 4:107679. doi: 10.1016/j.toxicon.2024.107679. Online ahead of print.ABSTRACTThe search for mechanism-based anti-inflammatory therapies is of fundamental importance to avoid undesired off-target effects. Phospholipase A2 (PLA2) activity is a potential molecular target for anti-inflammatory drugs because it fuels arachidonic acid needed to synthesize inflammation mediators, such as prostaglandins. Herein, we aim to investigate the molecular mechanism by which β-keto amyrin isolated from a methanolic extract of Cryptostegia grandiflora R. Br. Leaves can inhibit inflammation caused by Daboia russellii viper ...
Source: Toxicon - March 6, 2024 Category: Toxicology Authors: K H Santhosh V Krishna K Kemparaju H Manjunatha R Shashi Kumar Mukherjee Arnab S E Gomez Mejiba D C Ramirez B S Ravindranath Source Type: research
Adsorption Capacity of Carbon-Silica Composites towards Diclofenac in Poly(acrylic acid) Containing Systems: A Crucial Study on Common Wastewater Contaminants
Chemphyschem. 2024 Mar 2:e202300813. doi: 10.1002/cphc.202300813. Online ahead of print.ABSTRACTDiclofenac is one of the most popular over-the-counter non-steroidal anti-inflammatory drug and poly(acrylic acid) is a frequently used as thickener, filler or stabilizer. For these reasons, they are common organic contaminants in raw wastewater. The purpose of the presented studies was to compare the adsorption capacity of three carbon-silica composites - metal-free C/SiO2, iron-enriched C/Fe/SiO2 and manganese-enriched C/Mn/SiO2 towards diclofenac. The studies were carried out in single, and mixed systems in the presence of po...
Source: Chemphyschem - March 2, 2024 Category: Chemistry Authors: Magdalena Medykowska Ma łgorzata Wiśniewska Katarzyna Szewczuk-Karpisz Mariia Galaburda Source Type: research
A novel and sustainable composite of L@PSAC for superior removal of pharmaceuticals from different water matrices: Production, characterization, and application
This study endeavors to develop cost-effective environmentally friendly technology for removing harmful residual pharmaceuticals from water and wastewater by utilizing the effective adsorption of pistachio shell (PS) biochar and the degradation potency of laccase immobilized on the biochar (L@PSAC). The carbonatization and activation of the shells were optimized regarding temperature, time, and NH4NO3/PS ratio. This step yielded an optimum PS biochar (PSAC) with the highest porosity and surface area treated at 700 °C for 3 h using an NH4NO3/PS ratio of 3% wt. The immobilization of laccase onto PSAC (L@PSAC) was at its bes...
Source: Environmental Research - March 2, 2024 Category: Environmental Health Authors: Osamah J Al-Sareji Shatha Y Al Samarrai Ruqayah Ali Grmasha M ónika Meiczinger Raed A Al-Juboori Mikl ós Jakab Viola Somogyi Norbert Miskolczi Khalid S Hashim Source Type: research
Adsorption Capacity of Carbon-Silica Composites towards Diclofenac in Poly(acrylic acid) Containing Systems: A Crucial Study on Common Wastewater Contaminants
Chemphyschem. 2024 Mar 2:e202300813. doi: 10.1002/cphc.202300813. Online ahead of print.ABSTRACTDiclofenac is one of the most popular over-the-counter non-steroidal anti-inflammatory drug and poly(acrylic acid) is a frequently used as thickener, filler or stabilizer. For these reasons, they are common organic contaminants in raw wastewater. The purpose of the presented studies was to compare the adsorption capacity of three carbon-silica composites - metal-free C/SiO2, iron-enriched C/Fe/SiO2 and manganese-enriched C/Mn/SiO2 towards diclofenac. The studies were carried out in single, and mixed systems in the presence of po...
Source: Chemphyschem - March 2, 2024 Category: Chemistry Authors: Magdalena Medykowska Ma łgorzata Wiśniewska Katarzyna Szewczuk-Karpisz Mariia Galaburda Source Type: research
Adsorption Capacity of Carbon-Silica Composites towards Diclofenac in Poly(acrylic acid) Containing Systems: A Crucial Study on Common Wastewater Contaminants
Chemphyschem. 2024 Mar 2:e202300813. doi: 10.1002/cphc.202300813. Online ahead of print.ABSTRACTDiclofenac is one of the most popular over-the-counter non-steroidal anti-inflammatory drug and poly(acrylic acid) is a frequently used as thickener, filler or stabilizer. For these reasons, they are common organic contaminants in raw wastewater. The purpose of the presented studies was to compare the adsorption capacity of three carbon-silica composites - metal-free C/SiO2, iron-enriched C/Fe/SiO2 and manganese-enriched C/Mn/SiO2 towards diclofenac. The studies were carried out in single, and mixed systems in the presence of po...
Source: Chemphyschem - March 2, 2024 Category: Chemistry Authors: Magdalena Medykowska Ma łgorzata Wiśniewska Katarzyna Szewczuk-Karpisz Mariia Galaburda Source Type: research
Adsorption Capacity of Carbon-Silica Composites towards Diclofenac in Poly(acrylic acid) Containing Systems: A Crucial Study on Common Wastewater Contaminants
Chemphyschem. 2024 Mar 2:e202300813. doi: 10.1002/cphc.202300813. Online ahead of print.ABSTRACTDiclofenac is one of the most popular over-the-counter non-steroidal anti-inflammatory drug and poly(acrylic acid) is a frequently used as thickener, filler or stabilizer. For these reasons, they are common organic contaminants in raw wastewater. The purpose of the presented studies was to compare the adsorption capacity of three carbon-silica composites - metal-free C/SiO2, iron-enriched C/Fe/SiO2 and manganese-enriched C/Mn/SiO2 towards diclofenac. The studies were carried out in single, and mixed systems in the presence of po...
Source: Chemphyschem - March 2, 2024 Category: Chemistry Authors: Magdalena Medykowska Ma łgorzata Wiśniewska Katarzyna Szewczuk-Karpisz Mariia Galaburda Source Type: research
Hyaluronic acid from bleufin tuna by-product: Structural analysis and pharmacological activities
Int J Biol Macromol. 2024 Feb 28:130424. doi: 10.1016/j.ijbiomac.2024.130424. Online ahead of print.ABSTRACTThe fishing and aquaculture industries generate a huge amount of waste during processing and preservation operations, especially those of tuna. Recovering these by-products is a major economic and environmental challenge for manufacturers seeking to produce new active biomolecules of interest. A new hyaluronic acid was extracted from bluefin tuna's vitreous humour to assess its antioxidant and pharmacological activities. The characterization by infrared spectroscopy (FT-IR), nuclear magnetic resonance ((1D1H) and 2D ...
Source: International Journal of Biological Macromolecules - March 1, 2024 Category: Biochemistry Authors: Sawsen Elhiss Assia Hamdi Latifa Chahed Catherine Boisson-Vidal Hatem Majdoub Nadia Bouchemal Jamila Laschet Jamil Kraiem Didier Le Cerf Raoui Mounir Maaroufi Fr édéric Chaubet Mohamed Ben Mansour Source Type: research
Design of low-cost natural casein biopolymer based adsorbent for efficient adsorption of multiple anionic dyes and diclofenac sodium from aqueous solutions
Chemosphere. 2024 Feb 27:141571. doi: 10.1016/j.chemosphere.2024.141571. Online ahead of print.ABSTRACTThe treatment of various organic pollutants from industrial wastewater using bio-based materials has gained significant attention owing to their excellent properties such as low-cost, eco-friendly, non-toxic, and biodegradability. In this perspective, casein (Cn), a protein-based biopolymer, was extracted from the cow milk as a low-cost adsorbent, and the adsorption performances were determined for the pristine Cn. The adsorbent was employed for the removal of two different classes of targeted pollutant anionic dyes such ...
Source: Chemosphere - February 29, 2024 Category: Chemistry Authors: Vinayak Hegde U T Uthappa PadmajaV Mane Seong Min Ji Maduru Suneetha Ben Wang Tariq Altalhi T M Subrahmanya Mahaveer D Kurkuri Source Type: research
Design of low-cost natural casein biopolymer based adsorbent for efficient adsorption of multiple anionic dyes and diclofenac sodium from aqueous solutions
Chemosphere. 2024 Feb 27:141571. doi: 10.1016/j.chemosphere.2024.141571. Online ahead of print.ABSTRACTThe treatment of various organic pollutants from industrial wastewater using bio-based materials has gained significant attention owing to their excellent properties such as low-cost, eco-friendly, non-toxic, and biodegradability. In this perspective, casein (Cn), a protein-based biopolymer, was extracted from the cow milk as a low-cost adsorbent, and the adsorption performances were determined for the pristine Cn. The adsorbent was employed for the removal of two different classes of targeted pollutant anionic dyes such ...
Source: Chemosphere - February 29, 2024 Category: Chemistry Authors: Vinayak Hegde U T Uthappa PadmajaV Mane Seong Min Ji Maduru Suneetha Ben Wang Tariq Altalhi T M Subrahmanya Mahaveer D Kurkuri Source Type: research
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes - detailed studies on CYP3A inhibitors
In conclusion, we identified several glucuronide metabolites with CYP inhibitory properties. Based on detailed experiments, the inactivation of CYP3A by carvedilol may cause clinically significant drug-drug interactions.PMID:38423227 | DOI:10.1016/j.ejps.2024.106735 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - February 29, 2024 Category: Drugs & Pharmacology Authors: Helin ä Kahma Marie-No ëlle Paludetto Mikko Neuvonen Mika Kurkela Anne M Filppula Mikko Niemi Janne T Backman Source Type: research
