Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
CONCLUSIONS: This overview summarises the evidence of nine SRs investigating the effect of postnatal corticosteroids in preterm infants at risk for BPD. Late initiated (≥ seven days after birth) systemic administration of dexamethasone is considered an effective intervention to reduce the risk of BPD in infants with a high risk profile for BPD, based on a favourable balance between benefits and harms. Endotracheal instillation of corticosteroids (budesonide) with surfactant as a carrier is a promising intervention, based on the beneficial effect on desirable outcomes without (so far) negative side effects. Pending result...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Moniek van de Loo Anton van Kaam Martin Offringa Lex W Doyle Chris Cooper Wes Onland Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
CONCLUSIONS: This overview summarises the evidence of nine SRs investigating the effect of postnatal corticosteroids in preterm infants at risk for BPD. Late initiated (≥ seven days after birth) systemic administration of dexamethasone is considered an effective intervention to reduce the risk of BPD in infants with a high risk profile for BPD, based on a favourable balance between benefits and harms. Endotracheal instillation of corticosteroids (budesonide) with surfactant as a carrier is a promising intervention, based on the beneficial effect on desirable outcomes without (so far) negative side effects. Pending result...
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Moniek van de Loo Anton van Kaam Martin Offringa Lex W Doyle Chris Cooper Wes Onland Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
A sericin hydrogel scaffold for sustained dexamethasone release modulates macrophage polarization to promote mandibular bone defect repair in rats
CONCLUSION: The SMH-CD/DEX scaffold capable of sustained dexamethasone release promotes osteogenic differentiation of stem cells and bone defect repair in rats by regulating M2 polarization.PMID:38597445 | PMC:PMC11006699 | DOI:10.12122/j.issn.1673-4254.2024.03.15 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: Y Fan M Luo D Huang L Liu B Fu X Wang M Guan H Li Source Type: research
