Reuse of Nasoseptal Flaps for Endoscopic Endonasal Skull Base Reconstruction
Conclusions NSF reuse is effective at preventing postoperative CSF leak. The primary predictors of leak are high-flow intraoperative leak and inadequate defect coverage with NSF, regardless of the operation number. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - August 4, 2023 Category: Neurosurgery Authors: Bobeff, Ernest J. Mathios, Dimitrios Longo, Davide Estin, Joshua Joshua, Shejoy Tabaee, Abtin Kacker, Ashutosh Anand, Vijay K. Schwartz, Theodore H. Tags: Original Article Source Type: research

Bariatric surgery for hypothalamic obesity in craniopharyngioma patients: A literature review
Asian J Surg. 2023 Aug 1:S1015-9584(23)01125-9. doi: 10.1016/j.asjsur.2023.07.117. Online ahead of print.NO ABSTRACTPMID:37537035 | DOI:10.1016/j.asjsur.2023.07.117 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - August 3, 2023 Category: Surgery Authors: Hui-Zheng Hu Lei Lei Source Type: research

Reducing CSF complications by a recycled Hadad ’s flap combined with autologous mucosa in secondary endoscope transsphenoidal surgery
ConclusionA recycled HBF incorporated with an autologous mucosa is reliable for reconstructing the skull base in secondary transsphenoidal surgery, especially for patients simultaneously suffering from diabetes mellitus and central skull base tumors. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 2, 2023 Category: Cancer & Oncology Source Type: research

The feasibility and acceptability of mobile ecological momentary assessment to evaluate sleep, family functioning, and affect in patients with pediatric craniopharyngioma
. (Source: Journal of Psychosocial Oncology)
Source: Journal of Psychosocial Oncology - August 1, 2023 Category: Cancer & Oncology Authors: Nour Al Ghriwati Marcia Winter Joshua Semko Thomas E. Merchant Valerie McLaughlin Crabtree Source Type: research

Imaging of pituitary tumors: an update with the 5th WHO Classifications —part 2. Neoplasms other than PitNET and tumor-mimicking lesions
AbstractMany types of tumors can develop in the pituitary gland. In the recently revised 5th editions of the World Health Organization (WHO) classifications (2021 WHO Classification of Central Nervous System Tumors and the 2022 WHO Classification of Endocrine and Neuroendocrine Tumors), various changes have been made to the tumors other than pituitary neuroendocrine tumor (PitNET)/pituitary adenoma, as well as PitNET. Adamantinomatous craniopharyngioma and papillary craniopharyngioma are now considered separate tumors in the 5th edition of the WHO classification. Tumors positive for thyroid transcription factor 1, a marker...
Source: Japanese Journal of Radiology - July 27, 2023 Category: Radiology Source Type: research

BRAF plus MEK inhibition effective in papillary craniopharyngioma
Nature Reviews Clinical Oncology, Published online: 25 July 2023; doi:10.1038/s41571-023-00807-5BRAF plus MEK inhibition effective in papillary craniopharyngioma (Source: Nature Reviews Clinical Oncology)
Source: Nature Reviews Clinical Oncology - July 25, 2023 Category: Cancer & Oncology Authors: Peter Sidaway Source Type: research

Craniopharyngioma in Pediatrics and Adults
Adv Exp Med Biol. 2023;1405:299-329. doi: 10.1007/978-3-031-23705-8_11.ABSTRACTCraniopharyngiomas are rare malignancies of dysembryogenic origin, involving the sellar and parasellar areas. These low-grade, epithelial tumors account for two main histological patterns (adamantinomatous craniopharyngioma and papillary craniopharyngioma), which differ in epidemiology, pathogenesis, and histomorphological appearance. Adamantinomatous craniopharyngiomas typically show a bimodal age distribution (5-15 years and 45-60 years), while papillary craniopharyngiomas are limited to adult patients, especially in the fifth and sixth decade...
Source: Advances in Experimental Medicine and Biology - July 15, 2023 Category: Research Authors: Martina Piloni Filippo Gagliardi Michele Bailo Marco Losa Nicola Boari Alfio Spina Pietro Mortini Source Type: research

Dabrafenib as a diagnostic and therapeutic strategy for the non-surgical management of papillary craniopharyngioma
ConclusionPatients with a suspected papillary craniopharyngioma can be challenged with dabrafenib as a potentially effective diagnostic and therapeutic strategy, given that rapid regression with dabrafenib is only observed in tumors harboring aBRAF V600 mutation. Further work is needed to explore the optimal regimen and dose of the targeted therapy. (Source: Pituitary)
Source: Pituitary - July 10, 2023 Category: Endocrinology Source Type: research

Delayed epiphyseal closure in an adult with panhypopituitarism detected by 99mTc ‐MDP bone SPECT/CT
We reported a 23-year-old male patient with panhypopituitarism who underwent two resections for craniopharyngioma and received postoperative hormone replacement therapy. The99mTc-MDP bone scan revealed focal high uptake of radioactive nuclide in multiple large joints. The SPECT/CT demonstrated the focal high uptake in their metaphysis. Thus, delayed epiphyseal closure was considered. (Source: Clinical Case Reports)
Source: Clinical Case Reports - July 5, 2023 Category: General Medicine Authors: Yu Ning, Xiaoji Liu, Yao Chen, Min Cai, Sijin Li Tags: CASE REPORT Source Type: research