Immunoglobulin G4 hypophysitis in a 63-year-old woman with no autoimmune history: a case report
ConclusionThe case contributes to the growing clinicopathologic description of immunoglobulin-G4-related hypophysitis and illustrates that this diagnosis should be a consideration even outside the conventional demographic setting. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - September 5, 2021 Category: General Medicine Source Type: research

Primary ectopic parasellar craniopharyngioma: a case report
Craniopharyngioma (CP) is a slow-growing, benign tumor of the central nervous system located within the sellar and suprasellar regions. The tumor may extend from the suprasellar region to other areas. CPs are ... (Source: BMC Neurology)
Source: BMC Neurology - September 3, 2021 Category: Neurology Authors: Xintao Cai, Zhixiang Sun, Yu Li, Dongqi Shao, Xialin Zheng, Yu Wang and Zhiquan Jiang Tags: Case report Source Type: research

Typing of inflammatory lesions of the pituitary
AbstractInflammatory pituitary lesions account for 1.8% of all specimens from the German Pituitary Tumor Registry. They occure in 0.5% of the autoptical specimens and in 2.2% of the surgical cases. Women are significantly more often affected than men and are often younger when first diagnosed. In general, primary and secondary inflammation can be distinguished, with secondary types occurring more frequently (75.1%) than idiopathic inflammatory lesions (15.4%). In primary inflammation, the lymphocytic type is more common (88.5%) than the granulomatous type of hypophysitis (11.5%). The most common causes of secondary inflamm...
Source: Pituitary - August 31, 2021 Category: Endocrinology Source Type: research

Vision-related quality-of-life in pediatric primary brain tumor patients
ConclusionsPediatric brain tumor patients ’ vision, HR-QOL, and VR-QOL were often severely affected even when tumors were considered cured. Visual acuity and legal blindness correlated with VR-QOL. Systematic neuro-ophthalmologic examinations in pediatric primary brain tumor patients are necessary to facilitate early preventative and corr ective ophthalmologic interventions. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - August 30, 2021 Category: Cancer & Oncology Source Type: research

Strictly third ventricle craniopharyngiomas: pathological verification, anatomo-clinical characterization and surgical results from a comprehensive overview of 245 cases
This study thoroughly analyzes the largest series of strictly 3V CPs ever collected. From 5346 CP reports published between 1887 and 2021, we selected 245 cases with reliable pathological, surgical, and/or neuroradiological ve rification of an intact 3VF beneath the tumor. This specific topography occurs predominantly in adult (92.6%), male (64.4%) patients presenting with headache (69.2%), and psychiatric disturbances (59.2%). Neuroradiological features defining strictly 3V CPs are a tumor-free chiasmatic cistern (95.9%) , an entirely visible pituitary stalk (86.4%), and the hypothalamus positioned around the tumor’s lo...
Source: Neurosurgical Review - August 27, 2021 Category: Neurosurgery Source Type: research

Natural pregnancy after gross total resection of a large craniopharyngioma with hypothalamic involvement: a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - August 18, 2021 Category: Neurology Source Type: research

Descriptive epidemiology of craniopharyngiomas in the United States
ConclusionsCraniopharyngiomas are rare tumors with a bimodal age distribution and an equal male-to-female incidence. Black patients had the highest incidence, and adamantinomatous craniopharyngiomas were significantly more common than papillary tumors in adolescent, adult, and elderly populations. (Source: Pituitary)
Source: Pituitary - August 1, 2021 Category: Endocrinology Source Type: research

Three cases of ocular neuromyotonia associated with proton beam therapy
We report 3 cases of pediatric ocular neuromyotonia (ONM) following proton beam therapy (PBT) for craniopharyngioma. This complication has not been reported following PBT. (Source: Journal of AAPOS)
Source: Journal of AAPOS - August 1, 2021 Category: Opthalmology Authors: Cody Richardson, Casey Smith, Thomas Merchant, Raja Khan, Mary E. Hoehn Source Type: research

PH-0170 Proton therapy for adult craniopharyngioma
(Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - August 1, 2021 Category: Radiology Authors: N. Scher, R. Bentahila, C. Alapetite, A. Beddok, S. Helfre, S. Bolle, H. Mammar, R. Dendale, V. Calugaru, L. Feuvret Tags: Poster highlights: Poster Highlights 6: CNS 1 Source Type: research

Bariatric interventions in craniopharyngioma patients - Best choice or last option for treatment of hypothalamic obesity?
J Clin Endocrinol Metab. 2021 Jul 31:dgab567. doi: 10.1210/clinem/dgab567. Online ahead of print.NO ABSTRACTPMID:34331765 | DOI:10.1210/clinem/dgab567 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 31, 2021 Category: Endocrinology Authors: Hermann L M üller Source Type: research

Bariatric interventions in craniopharyngioma patients - Best choice or last option for treatment of hypothalamic obesity?
J Clin Endocrinol Metab. 2021 Jul 31:dgab567. doi: 10.1210/clinem/dgab567. Online ahead of print.NO ABSTRACTPMID:34331765 | DOI:10.1210/clinem/dgab567 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 31, 2021 Category: Endocrinology Authors: Hermann L M üller Source Type: research

Risk Factors for Hypothalamic Obesity in Patients With Adult-Onset Craniopharyngioma: A Consecutive Series of 120 Cases
ConclusionsHO is a common complication in patients with adult-onset craniopharyngioma. Patients with higher preoperative BMI had a greater risk for developing HO postoperatively. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - July 28, 2021 Category: Endocrinology Source Type: research

Safety of growth hormone (GH) treatment in GH deficient children and adults treated for cancer and non-malignant intracranial tumors —a review of research and clinical practice
AbstractIndividuals surviving cancer and brain tumors may experience growth hormone (GH) deficiency as a result of tumor growth, surgical resection and/or radiotherapy involving the hypothalamic-pituitary region. Given the pro-mitogenic and anti-apoptotic properties of GH and insulin-like growth factor-I, the safety of GH replacement in this population has raised hypothetical safety concerns that have been debated for decades. Data from multicenter studies with extended follow-up have generally not found significant associations between GH replacement and cancer recurrence or mortality from cancer among childhood cancer su...
Source: Pituitary - July 25, 2021 Category: Endocrinology Source Type: research