Deep-learning-based automatic segmentation and classification for craniopharyngiomas
ConclusionsThe automatic segmentation model can perform accurate multi-structure segmentation based on MRI, which is conducive to clearing tumor location and initiating intraoperative neuronavigation. The proposed automatic classification model and clinical scale based on automatic segmentation results achieve high accuracy in the QST classification, which is conducive to developing surgical plans and predicting patient prognosis. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - May 5, 2023 Category: Cancer & Oncology Source Type: research

The influence of tumor topography on the surgical outcome of craniopharyngiomas
CONCLUSIONS: The tumor topography can influence the postoperative outcome. RCPs can be associated with a higher incidence of hypopituitarism and hypothalamic morbidities postoperatively. The influence of topography on EOR and tumor recurrence is controversial. However, this study did not find a significant difference in EOR and tumor recurrence between RCPs and non-RCPs. PFS and overall mortality are also comparable.PMID:37119112 | DOI:10.3171/2023.3.JNS222302 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 29, 2023 Category: Neurosurgery Authors: Saravanan Sadhasivam Girish Menon Mathew Abraham Rajnish Kumar Arora Suresh Narayanan Nair Source Type: research

Predictors of extent of resection and recurrence following endoscopic endonasal resection of craniopharyngioma
CONCLUSIONS: The study data show that GTR should be the goal of surgery in craniopharyngiomas if it can be achieved safely. Although stalk preservation can maintain some endocrine function, the risk of recurrence is higher in such cases. Radiation may not be as effective as previously reported.PMID:37119110 | DOI:10.3171/2023.3.JNS222607 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 29, 2023 Category: Neurosurgery Authors: Ernest J Bobeff Dimitrios Mathios Adina A Mistry Georgiana A Dobri Mark M Souweidane Vijay K Anand Abtin Tabaee Ashutosh Kacker Jeffrey P Greenfield Theodore H Schwartz Source Type: research

Anton de Haen (1704-1776) and his extraordinary "portentosum infundibulum" case: the futile skull cauterization of a blind patient with a craniopharyngioma
J Neurosurg. 2023 Apr 28:1-10. doi: 10.3171/2023.3.JNS2381. Online ahead of print.ABSTRACTAnton de Haen (1704-1776) became one of the most influential physicians in the Habsburg Empire as a reformer of clinical instruction at Vienna Citizen's Hospital (Bürgerspital), where he introduced the bedside teaching method he had learned from Herman Boerhaave in Leyden, Holland. He also promoted the meticulous recording of clinical observations and the use of postmortem studies to identify the cause of death in hospitalized patients. Among the numerous clinicopathological reports compiled in his monumental 18-volume work Rationis ...
Source: Journal of Neurosurgery - April 29, 2023 Category: Neurosurgery Authors: Jos é María Pascual Ruth Prieto Maria Rosdolsky Verena Hofecker Source Type: research

The influence of tumor topography on the surgical outcome of craniopharyngiomas
CONCLUSIONS: The tumor topography can influence the postoperative outcome. RCPs can be associated with a higher incidence of hypopituitarism and hypothalamic morbidities postoperatively. The influence of topography on EOR and tumor recurrence is controversial. However, this study did not find a significant difference in EOR and tumor recurrence between RCPs and non-RCPs. PFS and overall mortality are also comparable.PMID:37119112 | DOI:10.3171/2023.3.JNS222302 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 29, 2023 Category: Neurosurgery Authors: Saravanan Sadhasivam Girish Menon Mathew Abraham Rajnish Kumar Arora Suresh Narayanan Nair Source Type: research