Impact of the Lumbar Catheter on the Incidence of Postsurgical Meningitis in the Endoscopic Endonasal Approach
Conclusions This study demonstrates an extremely high incidence of meningitis (36%) following EEA procedures when an LC is used. The incidence of meningitis was not significantly associated with CSF leak in our cohort. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - May 7, 2024 Category: Neurosurgery Authors: Maskin, Luis Patricio Noya, Santiago E. Caffaratti, Guido Echarri, Maria Martina Hlavnicka, Alejandro Cervio, Andres Tags: Original Article Source Type: research

Correction to: Customized ventral bony and dural opening in the transplanum/transtuberculum and transclival variants of extended endoscopic endonasal approach to suprasellar craniopharyngiomas: an approach ‑based stepwise cadaveric dissection and clinical applicability
(Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - May 7, 2024 Category: Neurosurgery Source Type: research

Endoscopic Endonasal Approach for Residual and Recurrent Craniopharyngioma after Transcranial Approach: A Multi-institutional Experience
Conclusions EEA achieves reasonable GTR rates and is an effective, safe surgical option for recurrent CP postinitial TCA. This approach demonstrated stable or improved visual and endocrinologic outcomes in all patients within our two-institution series. Thus, EEA should be considered as an efficacious form of retreatment in cases of progressive and recurrent CP. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - May 3, 2024 Category: Neurosurgery Authors: Jani, Ronak H. Raju, Sudesh Kim, Miri Gardner, Paul Zenonos, Georgios A. Snyderman, Carl Wang, Eric W. Patel, Chirag Germanwala, Anand V. Tags: Original Article Source Type: research

Targeted therapy in BRAF  mutated aggressive papillary craniopharyngioma: a case report and overview of the literature
ConclusionsOur study confirms the excellent response of papillary craniopharyngioma to combined BRAF and MEK inhibitors. However, rapid tumor recurrence is the rule when medical therapy is stopped. Resistance to a second and third course of targeted therapy did not occur, suggesting that tumor mutations affecting the response to drugs seems an uncommon event in papillary craniopharyngioma. The exact role of targeted therapy in the treatment algorithm of papillary craniopharyngiomas has still to be refined. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 2, 2024 Category: Endocrinology Source Type: research

Interdisziplin äre Behandlung von SchädelbasistumorenInterdisciplinary Management of Skull Base Tumors
Conclusion Interdisciplinary endonasal endoscopic surgery combines surgical expertise, improves resection rates for many pathologies, and minimizes morbidity by reducing the incidence of surgical complications. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Laryngo- Rhino- Otologie)
Source: Laryngo- Rhino- Otologie - May 2, 2024 Category: ENT & OMF Authors: Gerlach, Ruediger Modesti, Claudia Lodovica Rampinelli, Vittorio Tags: Referat Source Type: research

Pituitary abscess: a descriptive analysis of a series of 19 patients —a multi-center experience
ConclusionsGiven the lack of clarity in preoperative diagnosis, typical intraoperative findings and effective antibiotics treatment are more indicative of the correct diagnosis than other tests. In terms of therapy, optimal surgical intervention and active postoperative antibiotic treatment contribute to resolving the challenges posed by PA. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - May 2, 2024 Category: Research Source Type: research

Targeted therapy in BRAF  mutated aggressive papillary craniopharyngioma: a case report and overview of the literature
ConclusionsOur study confirms the excellent response of papillary craniopharyngioma to combined BRAF and MEK inhibitors. However, rapid tumor recurrence is the rule when medical therapy is stopped. Resistance to a second and third course of targeted therapy did not occur, suggesting that tumor mutations affecting the response to drugs seems an uncommon event in papillary craniopharyngioma. The exact role of targeted therapy in the treatment algorithm of papillary craniopharyngiomas has still to be refined. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 2, 2024 Category: Endocrinology Source Type: research

Supraorbital Keyhole Approach: Opening of the Frontal Sinus and Cerebrospinal Fluid Rhinorrhea
Conclusion: SOKHA is an excellent approach for anterior cranial fossa lesions especially with properly chosen cases. Incidence of CSF leak in our study is 1.1% and majority can be managed by placement of lumbar drain. Intraoperative obliteration of the frontal sinus can reduce the risk of postoperative CSF leak. A large frontal sinus needs not be a contraindication for SOKHA. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - April 30, 2024 Category: Neurosurgery Authors: Mehrotra, Anant Das, Kuntal Kanti Rangari, Kamlesh Kanjilal, Soumen Tataskar, Pooja Verma, Pawan Kumar Bhaisora, Kamlesh S. Jaiswal, Awadhesh Kumar, Raj Tags: Original Article Source Type: research

Efficacy of the Craniopharyngioma Resection via Expanded Endoscopic Endonasal Transsphenoidal Approach in the Treatment of Complex Craniopharyngioma and Its Effect on Pituitary Function and Complications of Patients
CONCLUSION: The craniopharyngioma resection via EETS has a significant therapeutic effect in complex craniopharyngioma with a high total tumor resection rate and clinical remission rate, which can protect the pituitary function of patients and provide more benefits for patients.PMID:38684506 | DOI:10.62713/aic.3145 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Xiongjian Bu Source Type: research