Reinvestigating Tumor –Ventricle Relationship of Craniopharyngiomas With Predominantly Ventricular Involvement: An Endoscopic Endonasal Series Based on Histopathological Assessment
ConclusionCPs with predominantly ventricular involvement should be considered as lesions with an extraventricular, epi-pia topography rather than “intraventricular” or “subpial” topography. Accurate understanding of the relationship between the third ventricle and such tumors would predict the circumferential cleavage plane of dissection, and remind neurosurgeons of performing dissection along the safe surgical plane to achieve total tumoral resection with minimizing hypothalamic damage. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 3, 2021 Category: Cancer & Oncology Source Type: research

Prediction of Post-operative Visual Deterioration Using Visual-Evoked Potential Latency in Extended Endoscopic Endonasal Resection of Craniopharyngiomas
Conclusions: The current study revealed that intraoperative VEP monitoring in EEEA is effective for predicting post-operative visual deterioration, and an extension over 8.61% in VEP latency can be used as a critical cut-off value to predict post-operative visual deterioration. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 3, 2021 Category: Neurology Source Type: research

Endocrine Disorder in Patients With Craniopharyngioma
This article reviews the latest research progress on pathogenesis, manifestation, significance, and treatment of endocrine disorders in patients with craniopharyngioma. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 2, 2021 Category: Neurology Source Type: research

Correction to: The eagle sign: a new preoperative MRI-based tool for predicting topographic correlation between craniopharyngioma and hypothalamus
(Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - December 2, 2021 Category: Cancer & Oncology Source Type: research

Radiotherapy alone for pediatric patients with craniopharyngioma
ConclusionRadiotherapy alone is an important treatment option to consider when radical resection is contraindicated, or surgical intervention is not required to alleviate symptoms. Disease control and functional outcomes are excellent after radiation therapy alone in appropriately selected patients. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - November 30, 2021 Category: Cancer & Oncology Source Type: research

Imaging Errors in Distinguishing Pituitary Adenomas From Other Sellar Lesions
Conclusions: Errors in imaging differentiation of pituitary adenoma from nonadenomatous lesions occurred often and sometimes with high confidence among a small sample of neurosurgeons and neuroradiologists. In the misdiagnosis of nonadenomatous lesions as adenomas, errors occurred largely from failure to appreciate a separate pituitary gland, but unavoidable errors occurred when large lesions had obliterated this distinguishing feature. In the misdiagnosis of adenomas as nonadenomatous lesions, avoidable errors occurred because readers failed to recognize imaging features more characteristic of adenomas and because cys...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Update on management of craniopharyngiomas
ConclusionEndoscopic technology has improved surgical results for craniopharyngiomas and expanded the indications for the transsphenoidal approach. The goal of CP surgery goal is maximal safe resection to achieve cure, but subtotal resection and radiation may be equally effective. Early diagnosis of specific variants will facilitate enrollment in promising medical trials. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - November 22, 2021 Category: Cancer & Oncology Source Type: research

Clinical Analysis of Risk Factors of Postoperative Psychiatric Disorders in Patients With Adult Craniopharyngioma
Conclusion: Neurocognitive assessment and intervention before and after surgery are important in patients with larger tumors, invading the third ventricle, and tumors with hypothalamic invasion. Prediction of these risk factors is essential for the treatment. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - November 17, 2021 Category: Neurology Source Type: research

Intraventricular Craniopharyngiomas —Overcoming Their Relative Inaccessibility: Institutional Experience With a Review of Literature
Conclusion: Purely IVCrs present with raised intracranial pressure, and visual disturbances are less common. Their deep-seated location and limited surgical field-of-view makes minimally invasive endoscopic-assisted surgery most suitable for their excision. The thin-walled cystic lesions may be occasionally adherent to the ependymal wall in close vicinity to the thalamus–hypothalamus complex, making complete excision difficult. Their responsiveness to radiotherapy, often leads to a gratifying long-term outcome. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - November 15, 2021 Category: Neurology Source Type: research

Cognitive interference processing in adults with childhood craniopharyngioma using functional magnetic resonance imaging
ConclusionAdults with childhood CP performed cognitive interference processing equally well as controls and demonstrated no compensatory fMRI activity in the CFP attention network compared to controls. This was also true for the two subgroups with and without hypothalamic injury. The results can be useful to better characterize this condition, and to optimize treatment and support for these individuals. (Source: Endocrine)
Source: Endocrine - November 11, 2021 Category: Endocrinology Source Type: research

The effect of radiation therapy and chemotherapy on malignant craniopharyngioma: A review
CONCLUSION: Malignant craniopharyngioma carries a dismal prognosis with no apparent benefits of radiation therapy and chemotherapy on survival.PMID:34754589 | PMC:PMC8571389 | DOI:10.25259/SNI_664_2021 (Source: Surgical Neurology International)
Source: Surgical Neurology International - November 10, 2021 Category: Neurosurgery Authors: Turki Elarjani Meshari Rashed Alhuthayl Hindi Alhindi Imad N Kanaan Source Type: research