Efficacy and safety of cysto-ventricular catheter implantation for space-occupying cysts arising from glioma and brain metastasis: a retrospective study
ConclusionsStereotactic implantation of CVC is an efficient treatment option for patients suffering from symptomatic space-occupying cysts from BMs or glioma, independently from their CNS WHO grade. However, a vigilant approach is crucial regarding potential complications and treatment failures. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - January 26, 2024 Category: Neurosurgery Source Type: research
Risk-benefit analysis of surgical treatment strategies for cystic craniopharyngioma in children and adolescents
ConclusionIn children and adolescents suffering from predominantly cystic craniopharyngiomas, stereotactic and microsurgical procedures can improve clinical symptoms at low procedural risk. Microsurgery, however, bears a higher risk of postoperative endocrine dysfunction. A risk-adapted surgical treatment concept may have to be applied repeatedly in order to achieve long-term tumor control even without additional irradiation. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - January 16, 2024 Category: Cancer & Oncology Source Type: research
First Local Experience of Intra-Cavitary Yttrium-90 Citrate Colloid Irradiation via Ommaya Reservoir for Refractory Cystic Craniopharyngioma: a Case Report
AbstractCraniopharyngioma is uncommon benign intracranial tumour that can be cured by surgical resection followed by conventional radiotherapy. However, its anatomical localisation makes the treatment hazardous or impossible. This case report aims to discuss the first local experience of using beta-emitting Yttrium-90 radioisotope in treating a patient with refractory cystic craniopharyngioma. A 43-year-old male who has underlying refractory cystic craniopharyngioma complicated with visual impairment and panhypopituitarism was referred to our nuclear medicine department for intra-cavitary irradiation therapy. Initially, he...
Source: Nuclear Medicine and Molecular Imaging - January 16, 2024 Category: Nuclear Medicine Source Type: research
Presentation and outcomes of paediatric craniopharyngioma in the west of Scotland: a 25 year experience
ConclusionOver 25 years the management of craniopharyngioma has changed substantially. Co-morbidities such as obesity are difficult to manage post-operatively and mortality risk can be up to 25% according to our cohort. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - January 15, 2024 Category: Cancer & Oncology Source Type: research
Isolated fourth ventricle craniopharyngioma: Representative case illustration and review of literature
CONCLUSION: The craniopharyngioma in our case was distinct because it was a solid tumor with no cystic component, exhibited homogeneous contrast enhancement in neuroimaging, developed in the fourth ventricle, and reached the level of foramen magnum, features that had rarely been documented previously. We also reviewed the literature on reported cases of 4th ventricular craniopharyngioma to strengthen knowledge in this area and highlight the embryological basis of ectopic craniopharyngioma.PMID:38213460 | PMC:PMC10783684 | DOI:10.25259/SNI_719_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - January 12, 2024 Category: Neurosurgery Authors: Nazmin Ahmed Md Isma Azam Source Type: research
Epigenetic control of adamantinomatous craniopharyngiomas
CONCLUSION: Two clusters of ACP patients were consistently revealed by unsupervised machine learning methods, being one of them significantly hypomethylated, enriched by CTNNB1 mutated ACPs, and associated with increased tumor size. Enrichment analysis reinforced pathways involved in tumor proliferation and in cell-specific tumoral microenvironment.PMID:38181427 | DOI:10.1210/clinem/dgae006 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - January 5, 2024 Category: Endocrinology Authors: Junier Marrero-Guti érrez Ana Carolina Bueno Clarissa Silva Martins Fernanda Borchers Coeli-Lacchini Rui M Patr ício Silva-Júnior Gabriel Henrique Marques Gon çalves Jorge Guilherme Okanobo Ozaki Danillo C de Almeida E Silva Luiz Eduardo Wildemberg Xi Source Type: research
Epigenetic control of adamantinomatous craniopharyngiomas
CONCLUSION: Two clusters of ACP patients were consistently revealed by unsupervised machine learning methods, being one of them significantly hypomethylated, enriched by CTNNB1 mutated ACPs, and associated with increased tumor size. Enrichment analysis reinforced pathways involved in tumor proliferation and in cell-specific tumoral microenvironment.PMID:38181427 | DOI:10.1210/clinem/dgae006 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - January 5, 2024 Category: Endocrinology Authors: Junier Marrero-Guti érrez Ana Carolina Bueno Clarissa Silva Martins Fernanda Borchers Coeli-Lacchini Rui M Patr ício Silva-Júnior Gabriel Henrique Marques Gon çalves Jorge Guilherme Okanobo Ozaki Danillo C de Almeida E Silva Luiz Eduardo Wildemberg Xi Source Type: research
Could setmelanotide be the game-changer for acquired hypothalamic obesity?
Children with acquired hypothalamic obesity, e.g. following treatment for pediatric craniopharyngioma are at great risk for metabolic syndrome, cardiovascular health problems and premature mortality. Treatment for acquired hypothalamic obesity has thus far been disappointing. Several interventions were reported to be partially successful, including dextro-amphetamine and GLP-1R agonists, although results in acquired hypothalamic obesity are conflicting. Disruption of signaling through the melanocortin-4 receptor (MC4R) pathway results in hyperphagia and severe early-onset hypothalamic obesity. Recently, the MC4R agonist se...
Source: Frontiers in Endocrinology - January 4, 2024 Category: Endocrinology Source Type: research
Cover Image
The cover image is based on the Case ReportNeurocysticercosis mimicking craniopharyngioma: A case report by Aliya F. Rehman et al.,https://doi.org/10.1002/ccr3.8166 (Source: Clinical Case Reports)
Source: Clinical Case Reports - December 26, 2023 Category: General Medicine Authors: Aliya F. Rehman,
Alex F. Lazo ‐Vasquez,
Parjanya K. Bhatt,
Tanya Quiroz,
Joelle‐Ann Joseph,
Sibel Gultekin,
Nadine Montreuil,
Candice A. Sternberg,
Folusakin Ayoade Tags: COVER IMAGE Source Type: research
Advances in the treatment of Adamantinomatous craniopharyngioma: How to balance tumor control and quality of life in the current environment: a narrative review
Adamantinomatous craniopharyngioma (ACP) presents a significant challenge to neurosurgeons despite its benign histology due to its aggressive behavior and unique growth patterns. This narrative review explores the evolving landscape of ACP treatments and their efficacy, highlighting the continuous development in therapeutic approaches in recent years. Traditionally, complete resection was the primary treatment for ACP, but surgical -related morbidity have led to a shift. The invasive nature of the finger-like protrusions in the histological structure results in a higher recurrence rate for ACP compared to papillary craniop...
Source: Frontiers in Oncology - December 21, 2023 Category: Cancer & Oncology Source Type: research
Cancers, Vol. 16, Pages 43: Congenital Tumors & mdash;Magnetic Resonance Imaging Findings with Focus on Rare Tumors
Cancers, Vol. 16, Pages 43: Congenital Tumors—Magnetic Resonance Imaging Findings with Focus on Rare Tumors
Cancers doi: 10.3390/cancers16010043
Authors:
Kwasniewicz
Wieczorek-Pastusiak
Romaniuk-Doroszewska
Bekiesinska-Figatowska
Congenital tumors are rare and, owing to this rarity, there is limited information on many of them. A total of 839 fetal and postnatal MRI studies performed in the first 3 months of life were retrospectively reviewed. They were performed with the use of 1.5 T scanners. Seventy-six tumors were diagnosed based on fetal MRI between 20 and 37 gestational weeks, and 27 were ...
Source: Cancers - December 20, 2023 Category: Cancer & Oncology Authors: Kwasniewicz Wieczorek-Pastusiak Romaniuk-Doroszewska Bekiesinska-Figatowska Tags: Article Source Type: research
Correction to: "GH and Childhood-onset Craniopharyngioma: When to Initiate GH Replacement Therapy?"
J Clin Endocrinol Metab. 2023 Dec 13:dgad721. doi: 10.1210/clinem/dgad721. Online ahead of print.NO ABSTRACTPMID:38092366 | DOI:10.1210/clinem/dgad721 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - December 13, 2023 Category: Endocrinology Source Type: research
Preoperative MRI diagnosis of papillary craniopharyngiomas: the revealing clues
(Source: Neurosurgical Review)
Source: Neurosurgical Review - December 8, 2023 Category: Neurosurgery Source Type: research
An institutional experience in applying quality improvement measures to pituitary surgery: clinical and resource implications
CONCLUSIONS: CCP implementation significantly improved LOS and costs of endoscopic endonasal resection, without adversely impacting postoperative ED presentations or readmissions.PMID:38039538 | DOI:10.3171/2023.9.FOCUS23545 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - December 1, 2023 Category: Neurosurgery Authors: Panayiotis E Pelargos Aamr Hasanjee Benjamin Lee Audrey Grossen Kiana Y Prather Xiaochun Zhao Prince Ohene-Nyako Matthew P Baier Amanda Kate McDaniel Kibwei A McKinney Christopher S Graffeo Edward El Rassi Ian F Dunn Source Type: research
An institutional experience in applying quality improvement measures to pituitary surgery: clinical and resource implications
CONCLUSIONS: CCP implementation significantly improved LOS and costs of endoscopic endonasal resection, without adversely impacting postoperative ED presentations or readmissions.PMID:38039538 | DOI:10.3171/2023.9.FOCUS23545 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - December 1, 2023 Category: Neurosurgery Authors: Panayiotis E Pelargos Aamr Hasanjee Benjamin Lee Audrey Grossen Kiana Y Prather Xiaochun Zhao Prince Ohene-Nyako Matthew P Baier Amanda Kate McDaniel Kibwei A McKinney Christopher S Graffeo Edward El Rassi Ian F Dunn Source Type: research
