Analysis of cases with co-infection of COVID-19 and pulmonary aspergillosis
This study included 201 COVID-19 patients from December 1, 2022, to January 31, 2023; 7 (3.5%) were diagnosed with CAPA. The main risk factors were age, MV, ICU admission and COPD, and the presence of comorbidities such as ARDS and hypoproteinemia in COVID-19 patients, more susceptible to Aspergillus infection. In addition to specimen culture in the lower respiratory tract, the 1,3-β-D-glucan antigen test can serve as an important screening indicator for early CAPA diagnosis in non-granulocytopenia patients.PMID:38700889 (Source: New Microbiologica)
Source: New Microbiologica - May 3, 2024 Category: Microbiology Authors: Hui Zheng Hu Li Bo Wu Qian Liu Bin Yan Wu Yu Wang Rui Ying Wang Source Type: research
Surgery for Central Nervous System Tuberculosis in Children
Adv Tech Stand Neurosurg. 2024;49:255-289. doi: 10.1007/978-3-031-42398-7_12.ABSTRACTTuberculosis (TB) is the second most common cause of death due to a single infectious agent worldwide after COVID-19. Central nervous system tuberculosis is widely prevalent in the world, especially in the developing countries and continues to be a socioeconomic problem. It is highly devastating form of tuberculosis leading to unacceptable levels of morbidity and mortality despite appropriate antitubercular therapy. The clinical symptoms are varied and nonspecific. They can be easily overlooked. Tuberculous meningitis is the most common pr...
Source: Advances and Technical Standards in Neurosurgery - May 3, 2024 Category: Neurosurgery Authors: Dattatraya Muzumdar Puru Bansal Survender Rai Kushal Bhatia Source Type: research
Complement system is overactivated in patients with IgA nephropathy after COVID-19
Clin Immunol. 2024 May 1:110232. doi: 10.1016/j.clim.2024.110232. Online ahead of print.ABSTRACTIgA nephropathy (IgAN), which has been confirmed as a complement mediated autoimmune disease, is also one form of glomerulonephritis associated with COVID-19. Here, we aim to investigate the clinical and immunological characteristics of patients with IgAN after COVID-19. The level of plasma level of C5a (p < 0.001), soluble C5b-9 (p = 0.018), FHR5 (p < 0.001) were all significantly higher in Group CoV (33 patients with renal biopsy-proven IgAN experienced COVID-19) compared with Group non-CoV (44 patients with IgAN without...
Source: Clinical Immunology - May 3, 2024 Category: Allergy & Immunology Authors: Wei-Yi Guo Guo-Qin Wang Ling-Qiang Kong Li-Jun Sun Xiao-Yi Xu Wen-Rong Cheng Hong-Rui Dong Hong Cheng Source Type: research
United States marijuana legalization and opioid mortality trends before and during the first year of the COVID-19 pandemic
CONCLUSIONS: During the past decade, marijuana legalization in the US was associated at the jurisdiction level with a greater acceleration in opioid death rate. An even greater increase in opioid mortality occurred in recreational-legalizing jurisdictions with the onset of the COVID-19 pandemic. Marijuana legalization is correlated with worsening of the US opioid epidemic.PMID:38700393 | DOI:10.5055/jom.0829 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Archie Bleyer Brian Barnes Kenneth Finn Source Type: research
Increased Pill Burden and Adverse Effects of Psychotropics Correlated with Poor Quality of Life and Medication Nonadherence: A Cross-sectional Drug Utilization Study at a Tertiary Care Hospital in Delhi during COVID-19 Pandemic
CONCLUSION: In the tertiary care hospital described, rational drug prescribing was followed. Increase in the number of drugs per prescription was found to be associated with poor QOL and the development of ADRs led to medication nonadherence in the patients. Further studies with larger sample sizes are needed to confirm these results. How to cite this article: Kumar A, Halder S, Srivastava S, et al. Increased Pill Burden and Adverse Effects of Psychotropics Correlated with Poor Quality of Life and Medication Nonadherence: A Cross-sectional Drug Utilization Study at a Tertiary Care Hospital in Delhi during COVID-19 Pandemic...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Ashish Kumar Sumita Halder Shruti Srivastava Rachna Gupta Source Type: research
A Cross-sectional Survey of Public Knowledge and Perspective on Coronavirus Disease, Vaccination, and Related Research in India during the COVID-19 Pandemic
CONCLUSION: The survey provides insight into the public awareness and perception of the pandemic that has taught all the lessons for capacity building in automation, construction of robust medical infrastructure, and the need for future preparedness. How to cite this article: Munshi R, Maurya M. A Cross-sectional Survey of Public Knowledge and Perspective on Coronavirus Disease, Vaccination, and Related Research in India during the COVID-19 Pandemic. J Assoc Physicians India 2023;71(9):19-27.PMID:38700297 | DOI:10.59556/japi.71.0335 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Renuka Munshi Miteshkumar Maurya Source Type: research
Humoral Response After Two Doses of COVISHIELD < sup > TM < /sup > Vaccine in Patients Undergoing Maintenance Hemodialysis
CONCLUSION: In MHD patients, two doses of the COVISHIELDTM vaccine induced a substantial humoral response. Prior history of COVID-19 resulted in a higher antibody response. Thus, the COVISHIELDTM vaccine is efficacious and safe for use in patients with MHD. How to cite this article: Balwani MR, Pasari AS, Baw.ule C, et al. Humoral Response After Two Doses of COVISHIELDTM Vaccine in Patients Undergoing Maintenance Hemodialysis. J Assoc Physicians India 2023;71(9):56-60.PMID:38700302 | DOI:10.59556/japi.71.0313 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Manish R Balwani Amit S Pasari Charulata Bawankule Amol Bhawane Priyanka Tolani Vijay M Katekhaye Source Type: research
Glycemic Control and Mucormycosis during COVID-19 Pandemic in India a Study of Stage and Outcome
CONCLUSION: The study showed a positive correlation between the stage of mucormycosis and serum glycemic control markers at presentation. Clinicians must order blood sugar and HbA1c levels at presentation as cues for a better understanding of disease severity. A thorough clinical examination and history taking for patient risk factors predisposing to mucormycosis are also crucial since the presence of proptosis and coronary artery disease are significantly correlated with the mortality outcomes. The extent of poor glycemic control at presentation was not associated with mortality outcomes. How to cite this article: Sharma ...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Vagisha Sharma Kushal Kriplani Isha P Tuli Shilpam Sharma Anurag Narula Source Type: research
Comparison of Guillain-Barre Syndrome Cases during and Prior to the COVID-19 Pandemic: A Multicentric Study
DISCUSSION: The number of GBS hospital admissions, clinical presentation, electrodiagnostic features, and short-term outcomes did not differ significantly between the prepandemic and postpandemic periods; a slightly higher incidence of in-hospital complications was observed during the pandemic period. How to cite this article: Panicker P, R D, V AG, et al. Comparison of Guillain-Barre Syndrome Cases during and Prior to the COVID-19 Pandemic: A Multicentric Study. J Assoc Physicians India 2023;71(9):69-71.PMID:38700304 | DOI:10.59556/japi.71.0317 (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Praveen Panicker Dileep R Abdul V Gafoor Prasanth S R Thomas Iype James Jose Antony Stanley Source Type: research
Long COVID-19: A Systematic Review
J Assoc Physicians India. 2023 Sep;71(9):82-94. doi: 10.59556/japi.71.0337.ABSTRACTCoronavirus disease 2019's (COVID-19's) wide dissemination casts long-term health jeopardy for millions. Long COVID-19, a lingering multisystem malady, weaves a complex array of symptoms. Understanding its full impact requires extensive research over months or years. The pace of recovery remains uncertain, challenging healthcare systems. An evidence-based symphony of medical care and support is urgently needed for long haulers. Understanding long COVID's genesis and advocating for patients is vital. Our comprehension remains limited, prompti...
Source: Journal of the Association of Physicians of India - May 3, 2024 Category: General Medicine Authors: Subrahmanyam Karuturi Source Type: research
Immunogenicity, Effectiveness, and Safety of COVID-19 Vaccines among Patients with Immune-Mediated Dermatological Diseases: A Systematic Review and Meta-analysis
In conclusion, immune-mediated dermatological diseases showed a reduced vaccine response in our meta-analysis, yet vaccination remained effective against COVID-19 infection and well tolerated.PMID:38698654 | DOI:10.2340/actadv.v104.40009 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 3, 2024 Category: Dermatology Authors: Sonphet Chirasuthat Yanisa Ratanapokasatit Kunlawat Thadanipon Kumutnart Chanprapaph Source Type: research
Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence
Aging (Albany NY). 2024 May 2;16. doi: 10.18632/aging.205787. Online ahead of print.ABSTRACTThe battle against the COVID-19 pandemic has spurred a heightened state of vigilance in global healthcare, leading to the proliferation of diverse sanitization methods. Among these approaches, germicidal lamps utilizing ultraviolet (UV) rays, particularly UV-C (wavelength ranging from 280 to 100 nm), have gained prominence for domestic use. These light-emitting diode (LED) lamps are designed to sanitize the air, objects, and surfaces. However, the prevailing concern is that these UV lamps are often introduced into the market without...
Source: Aging - May 3, 2024 Category: Biomedical Science Authors: Nicola Alessio Alessia Ambrosino Andrea Boggi Domenico Aprile Iole Pinto Giovanni Galano Umberto Galderisi Giovanni Di Bernardo Source Type: research
The End of the Beginning? Temporality and Bioagency in Pandemic Research
J Hist Med Allied Sci. 2024 May 3:jrae006. doi: 10.1093/jhmas/jrae006. Online ahead of print.ABSTRACTThis paper deals with the ways in which the intellectual and political history of AIDS can assist in the chronological conceptualization of a pandemic such as COVID-19 as it is unfolding. It problematizes the idea of pandemic "beginnings" and "ends" to show that such definitions are shaped by the disciplinary location and thematic foci of relevant scholars. Central to this analysis is the notion that ethical and political contexts affect research on a pandemic in different ways at national and global levels at various point...
Source: Medical History - May 3, 2024 Category: History of Medicine Authors: Mandisa Mbali Source Type: research
Surgical capacity is disaster preparedness: A scoping review of how surgery and anesthesiology departments responded to COVID-19
CONCLUSION: Our review reflects the mechanisms by which hospital surgical systems responded to the initial stress of the COVID-19 pandemic and reinforced the many changes to hospital policy that occurred in the pandemic. Healthcare systems with robust surgical systems were better able to cope with the initial stress of the COVID-19 pandemic. The well-resourced health systems of HICs reported rapid and dynamic changes by providers to assist in and ultimately improve the care of patients during the pandemic. Surgical system strengthening will allow health systems to be more resilient and prepared for the next disaster.PMID:3...
Source: American Journal of Disaster Medicine - May 3, 2024 Category: International Medicine & Public Health Authors: Matthew T Hey Madeleine Carroll Lili B Steel Mayte Bryce-Alberti Radzi Hamzah Rachel E Wittenberg Anam Ehsan Hodan Abdi Latoya Stewart Raina Parikh Raisa Rauf Jacqueline Cellini Kiana Winslow Isaac G Alty Craig D McClain Geoffrey A Anderson Source Type: research
COVID-19 Vaccine Information and Infertility Posts on X: Insights on a Misinformation Pandemic
CONCLUSIONS AND RELEVANCE: Misinformation about the COVID-19 vaccine and fertility is highly prevalent on X and threatens vaccine uptake in patients desiring future fertility. Accounts sharing factual information were likely to have more followers and be verified; therefore, verifying more physicians sharing accurate information is critical.PMID:38698715 | DOI:10.7812/TPP/23.142 (Source: The Permanente journal)
Source: The Permanente journal - May 3, 2024 Category: General Medicine Authors: Morgan S Levy Kelby N Hunt Sarah Rinehart Alyssa D Brown Amelia G Kelly Padmaja Sundaram Alisha Crump Tiffany J Sinclair Kally Dey Alexander Zoroufy Alberto J Caban-Martinez Torie Comeaux Plowden Source Type: research
