Talk Evidence - evidence in Roe vs Wade, MI treatment variation, and tribal methodologies
Helen Macdonald, The BMJ's research integrity editor is back with another episode, and this week is joined by Joe Ross, professor of medicine and public health at Yale, and US research editor for The BMJ, and Juan Franco, editor in chief of BMJ EBM, and Professor at the Instituto Universitario Hospital Italiano de Buenos Aires
In this episode they discuss;
The US supreme court looks set to overturn Roe v Wade, creating a patchwork of abortion provision across the U.S. We consider the role which evidence might play in documenting how health is affected by that decision, and whether medical evidence is being used at all i...
Source: The BMJ Podcast - May 23, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Talk Evidence - evidence in Roe vs Wade, MI treatment variation, and tribal methodologies
Helen Macdonald, The BMJ's research integrity editor is back with another episode, and this week is joined by Joe Ross, professor of medicine and public health at Yale, and US research editor for The BMJ, and Juan Franco, editor in chief of BMJ EBM, and Professor at the Instituto Universitario Hospital Italiano de Buenos Aires
In this episode they discuss;
The US supreme court looks set to overturn Roe v Wade, creating a patchwork of abortion provision across the U.S. We consider the role which evidence might play in documenting how health is affected by that decision, and whether medical evidence is being used at all in...
Source: The BMJ Podcast - May 23, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts
TWiV 902: Autoantibodies drive severe COVID-19
TWiV reviews recent cases of monkeypox, presence of SARS-CoV-2 RNA but not infectious virus in feces, and the association of autoantibodies to interferons with severe COVID-19. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox in MA (ProMed Mail) Possible monkeypox in NYC (NY Times) Occupational monkeypox, Wisconsin (Emerg Inf Dis) SARS-CoV-2 in feces (Nature) IFN autoantibodies and severe COVID-19 (PNAS) Letters read on TWiV 902 Timestamps by Jolene. T...
Source: This Week in Virology - MP3 Edition - May 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 901: COVID-19 clinical update #115 with Dr. Daniel Griffin
In COVID-19 clinical update #115, Dr. Griffin reviews cross-variant immunity without vaccination, EUA for boosters in 5-11 year olds, B.1.1.529 attack rate, scent dogs, Omicron and pets, Paxlovid, Veklury, Fluvoxamine, antigen positivity after isolation, inflammasome activation and severe disease, and GI persistence and fecal shedding. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Limited cross-variant immunity without vaccination (Nature) EUA for boosters in 5-11 year olds (FDA) Stages of COVID-19 (AIDS Rev) B.1.1.529 attack rate in Australia (JID) Sce...
Source: This Week in Virology - MP3 Edition - May 21, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Q & A With White House COVID-19 Response Coordinator Ashish Jha
As the White House’s COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government’s continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19. Related Content: New White House COVID-19 Leader on What’s Next Q&A With White House COVID-19 Response Coordinator Ashish Jha (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - May 18, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
SCCM Pod-457 CCM: Increased incidence of ventilator-acquired pneumonia in COVID-19 patient
While little is known about the epidemiology of ventilator-acquired pneumonia among COVID-19 patients, some studies suggest a higher risk of ventilator-associated pneumonia in this specific population. Ashish K. Khanna, MD, FCCP, FCCM, is joined by Charles-Herve Vacheron, MD, to discuss the Cohort exposed/nonexposed study among the REA-REZO surveillance network. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - May 16, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
TWiV 900: Burning down the mouse
TWiV celebrates 900 episodes, Vincent gives the Richard R. Ernst lecture, and we discuss why inflammasome activation in infected macrophages drives severe COVID-19. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Richard R. Ernst Lecture Infected macrophages drives severe COVID-19 (Nature) Timestamps by Jolene. Thanks! Weekly Picks Brianne – The Milky Way’s Black Hole Comes to Light Kathy – River dolphins playing with anaconda Rich – Smallpox vaccination techniq...
Source: This Week in Virology - MP3 Edition - May 15, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 899: COVID-19 clinical update #114 with Dr. Daniel Griffin
In COVID-19 clinical update #114, Dr. Griffin discusses early treatment with ivermectin, procalcitonin not a reliable biomarker, vaccine in 6-11 year olds, FDA limits use of Janssen vaccine, does site of vaccine booster matter, sniffer dogs, monoclonals for hospitalized patients, risk assessment for public events, Paxlovid eligibility, and persistence of pediatric anosmia. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Effects of early treatment with Ivermectin (NEJM) Procalcitonin not a reliable biomarker (IDSA) Evaluation of vaccine in children 6 t...
Source: This Week in Virology - MP3 Edition - May 14, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Coronapod: 'viral ghosts' support idea that SARS-CoV-2 reservoirs could be behind long COVID
Millions of people around the world have been left managing the complex and amorphous syndrome that is long COVID. But the underlying cause of this myriad of symptoms is not clear. One hypothesis is that the virus is able to find a safe haven in the body from which it can bide its time and potentially re-emerge - a viral reservoir. Now researchers studying long COVID have found evidence of SARS-CoV-2 in a series of organs around the body, most notably the gut, months after the infection appears to have been cleared from the respiratory system. While there is still a long way to go before the reservoir hypothesis can be con...
Source: Nature Podcast - May 13, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Do blood thinners prevent people who are hospitalised with COVID-19 from developing blood clots?
There are now more than two dozen Cochrane reviews of high priority topics relevant to COVID-19, which are being kept up to date as new evidence becomes available. In March 2022, we published updated findings on the effects of anticoagulants and we asked lead author, Ronald Flumignan from the Federal University of Sao Paulo in Brazil to summarize the evidence in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - May 13, 2022 Category: General Medicine Authors: Cochrane Source Type: podcasts
Fixing fat bubbles for vaccines, and preventing pain from turning chronic
On this week’s show: Lipid nanoparticles served us well as tiny taxis delivering millions of mRNA vaccines against COVID-19, but they aren’t optimized—yet, and why we might need inflammation to stop chronic pain
The messenger RNA payload of the mRNA vaccines against SARS-CoV-2 is wrapped up in little fatty packets called lipid nanoparticles (LNPs). These fat bubbles were originally designed for something much different—carrying molecules into cells to silence genes. But they were useful and we were in a hurry, so not much was changed about them when they were pressed into service against COVID-19. ...
Source: Science Magazine Podcast - May 12, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
Fixing fat bubbles for vaccines, and preventing pain from turning chronic
On this week’s show: Lipid nanoparticles served us well as tiny taxis delivering millions of mRNA vaccines against COVID-19, but they aren’t optimized—yet, and why we might need inflammation to stop chronic pain
The messenger RNA payload of the mRNA vaccines against SARS-CoV-2 is wrapped up in little fatty packets called lipid nanoparticles (LNPs). These fat bubbles were originally designed for something much different—carrying molecules into cells to silence genes. But they were useful and we were in a hurry, so not much was changed about them when they were pressed into service against COVID-19. Science journali...
Source: Science Magazine Podcast - May 12, 2022 Category: Science Authors: Science Magazine Source Type: podcasts
JAMA Psychiatry : Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections
Interview with Peter Watkinson, MD, and Julia Hippisley-Cox, MD, authors of Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections. Hosted by John Torous, MD, MBI. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - May 11, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 898: Immunity is skin deep
TWiV explains why the concept of herd immunity might not apply to COVID-19, and the observation that smallpox vaccination causes an increase in skin bacteria that promote pathology and influence the immune response. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Herd immunity may not apply to COVID-19 (J Inf Dis) Smallpox vaccination increases skin bacteria (PLoS Path) The invinceable TWiV (TWiV 145) By the pricking of my thumbs… (TWiV 284) Letters read on TWiV 898 Timestamps b...
Source: This Week in Virology - MP3 Edition - May 8, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 897: COVID-19 clinical update #113 with Dr. Daniel Griffin
In COVID-19 clinical update #113, Dr. Griffin discusses tocilizumab use in hospitalized Patients, IL-6 inhibitors and mortality, Baricitinib in hospitalized patients, post-infection neurological sequelae, comparative effectiveness of Pfizer and Moderna vaccines, phase 2/3 study of Paxlovid, infection relapse following Paxlovid, pre-hospital administration of Remdesivir, and hospitalization with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Timing of Tocilizumab Use in Hospitalized Patients (NIH) Interleukin-6 inhibitors redu...
Source: This Week in Virology - MP3 Edition - May 7, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
