TWiV 1052: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses disease severity of RSV compared with COVID-19 and Influenza among hospitalized adults aged ≥60 years, antiviral efficacy of Molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19, Nirmatrelvir-Ritonavir and COVID-19 mortality and hospitalization among patients with vulnerability to covid-19 complications, antibiotic use among hospitalized patients with COVID-19 in the United States, one week of oral Camostat vs Placebo in nonhospitalized adults with mild-to-moderate COVID-19, assessment of the available therapeutic approaches fo...
Source: This Week in Virology - MP3 Edition - October 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Gene edits move pig organs closer to human transplantation
In this episode:00:46 Engineered pig kidneys show transplantation promiseKidneys from genetically-engineered miniature pigs have been transplanted into non-human primates, in some cases keeping the animals alive for more than a year. Using CRISPR, a team made dozens of edits to the pig genome to prevent the monkeys’ immune system from attacking the organs. They also removed pig retrovirus genes that could represent an infection risk. These steps are necessary if pig organs are to be used in human transplants, something many clinicians and researchers think will be needed to overcome a critical shortage of organs for tran...
Source: Nature Podcast - October 11, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1051: Like SARS-CoV-2 in the headlights
TWiV reviews the 2023 Nobel Prize in Physiology or Medicine awarded to Katalin Karikó and Drew Weissman for their identification nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19, and accelerated mutation of SARS-CoV-2 in white-tailed deer. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant positi...
Source: This Week in Virology - MP3 Edition - October 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1050: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the effectiveness of maternal mRNA COVID-19 vaccination during pregnancy against COVID-19–associated hospitalizations in infants aged (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - October 7, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1048: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses a molnupiravir-associated mutational signature in global SARS-CoV-2 genomes, inhaled fluticasone furoate for outpatient treatment of COVID-19, optimal duration of systemic corticosteroids in COVID-19 treatment, early antibody treatment, inflammation, and risk of post-COVID conditions, autonomic dysregulation in long-term patients suffering from post-COVID-19 syndrome assessed by heart rate variability, and multiorgan MRI findings after hospitalization with COVID-19 in the UK. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Lin...
Source: This Week in Virology - MP3 Edition - September 30, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The Connection Between SARS-CoV-2 and Type 1 Diabetes Risk in Young Children
During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. Related Content: SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - September 26, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Lorundrostat for Hypertension, Autoimmunity After COVID-19, Childhood Cancer Survivor Care, and more
Editor’s Summary by Anne Rentoumis Cappola, MD, ScM, Senior Editor of JAMA, the Journal of the American Medical Association, for the September 26, 2023, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - September 26, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 1047: Long COVID and avian flu in ferrets
TWiV explains a study of postacute sequelae of COVID-19 at 2 years, and respiratory droplet transmission of human-isolated avian H3N8 influenza virus between ferrets. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) 4:20 Postacute sequelae of COVID-19 at 2 years (Nat Med) Disability-adjusted life years (DALYs) (WHO) Respiratory droplet transmission of H3N8 viru...
Source: This Week in Virology - MP3 Edition - September 24, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

SCCM Pod-492: The Long and Short of Long COVID
COVID-19 survivors who experience severe critical illness are at risk even when they leave the ICU. Long COVID is becoming recognized as a widespread problem, resulting in lower quality of life and productivity. Ludwig H. Lin, MD, is joined by E. Wesley Ely, MD, MHP, MCCM, to discuss the range of symptoms encompassing long COVID, as well as the latest research and treatment. Dr. Ely is a subspecialist in pulmonary and critical care medicine who conducts patient-oriented health services research as a professor of medicine in the Division of Allergy, Pulmonary, and Critical Care Medicine at Vanderbilt University Medical Cent...
Source: SCCM PodCast - iCritical Care - September 23, 2023 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 1046: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses wastewater surveillance data as a complement to emergency department visit data for tracking the incidence of influenza A and RSV, chatbot-delivered online intervention to promote seasonal Influenza vaccination during the COVID-19 pandemic, temporal assessment of disparities in California COVID-19 mortality by industry, modeling the impact of a high-uptake bivalent booster scenario on the COVID-19 burden and healthcare costs in New York City, can high COVID-19 vaccination rates in adults help protect unvaccinated children, Nirmatrelvir/Ritonavir use and hospitalizations ...
Source: This Week in Virology - MP3 Edition - September 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

JAMA Otolaryngology –Head & Neck Surgery : Efficacy of Gabapentin For Post –COVID-19 Olfactory Dysfunction
Interview with Jay F. Piccirillo, MD, author of Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Related Content: Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - September 21, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

TWiV 1044: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the immunogenicity and reactogenicity of coadministration of COVID-19 and Influenza vaccines, interim effectiveness estimates of 2023 southern hemisphere influenza vaccines in preventing Influenza-associated hospitalizations, genome-wide association study of susceptibility to RSV hospitalization in young children (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - September 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

SCCM Pod-491: Nursing the Wounds of Burnout
COVID-19 transformed healthcare and presented specific long-term challenges for the nursing profession. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, was joined by Norma J. Shoemaker Honorary Lecturer Ernest J. Grant, PhD, RN, FAAN, at the 2023 Critical Care Congress to discuss the shortage of critical care nurses. Survey results reveal that nurses continue to experience burnout and frustration. They discuss how to leverage data to best support nurses now and in the future. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - September 14, 2023 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 1043: Marion Koopmans on COVID-19, Mpox, H5N1, polio and One Health
From the European Society for Clinical Virology meeting in Milan, Vincent speaks with Marion Koopmans about COVID-19, Mpox, H5N1 and polio, and the promise of a One Health approach to prevent outbreaks, epidemics, and pandemics. Host: Vincent Racaniello Guest: Marion Koopmans Click arrow to play Download TWiV 1043 (45 MB .mp3, 62 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) SARS-CoV-2 variants in Rotterdam wastewater (Sci Tot Envi...
Source: This Week in Virology - MP3 Edition - September 10, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1042: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses China’s health authorities fighting surge in cases of Mpox unknown origin, analysis of seasonal variation of antibiotic prescribing for respiratory tract diagnoses in primary care practices, prevalence and associated outcomes of co-infection between SARS-CoV-2 and influenza, comparison of bivalent and monovalent mRNA vaccine boosters, optimal duration of systemic corticosteroids in COVID-19 treatment, acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization, temporal changes in fecal microbiota of patients infected with C...
Source: This Week in Virology - MP3 Edition - September 9, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts