TWiV 1072: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, op...
Source: This Week in Virology - MP3 Edition - December 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1070: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses monkeypox and chickenpox co-infection in southern Nigeria, vaccine effectiveness against influenza A, SARS-CoV-2 neutralizing antibody titers in maternal blood, umbilical cord blood, and breast milk, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, four methods for monitoring SARS-CoV-2 and Influenza A virus activity in schools, efficacy and safety of Baricitinib for the treatment of hospitalized adults with COVID-19, a synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong, consisten...
Source: This Week in Virology - MP3 Edition - December 16, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Inhaled vaccine prevents COVID in monkeys
Current COVID-19 vaccines offer great protection from serious illness, but they don't prevent people from becoming infected in the first place. Because of this, researchers have been searching for ways to boost mucosal immunity — the immune response on mucosal surfaces — as this is where the virus is first encountered by the body. Now a team have shown that mucosal immunity can be improved enough to block infection in rhesus macaques by administering booster vaccines directly into their lungs, through inhalation. They hope this could offer a way to stop humans getting COVID-19 in the ...
Source: Nature Podcast - December 14, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 1068: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses developmental impairment in children exposed during pregnancy to maternal SARS-COV2, vagus nerve dysfunction in the post-COVID-19 condition, and humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases, incidence and burden of long COVID in Africa. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Developmental impairment in children exposed during pregnancy to maternal SARS-COV2 (IJID) Vagus nerve dysfunction in the post-COVID-...
Source: This Week in Virology - MP3 Edition - December 9, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1066: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses a microbiologist who was harassed during COVID pandemic sues university, use of inactivated poliovirus vaccine for poliovirus outbreak response, safety and immunogenicity of bivalent rsvpref vaccine coadministered with seasonal inactivated influenza vaccine in older adults, coffee as a dietary strategy to prevent SARS-CoV-2 infection, enrollment of pediatric patients in COVID-19 interventional trials, vaccination, immunity, and the changing impact of COVID-19 on infant health, COVID-19 vaccine effectiveness against post- COVID -19 condition among 589722 individuals in Sw...
Source: This Week in Virology - MP3 Edition - December 2, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The future of the winter ’flu season
We were accepting of an increase in deaths every winter 'flu season, but Ashish Jha thinks that is not longer a tenable position. Lessons he learned during his time as the White House Covid-19 coordinator have convinced him we should be taking a different approach to the winter season. In this interview with Mun-Keat Looi, The BMJ's international features editor, we hear about living with COVID, the future of antivirals, vaccines, and surveillance. They talk about long COVID, the investment required to fight future outbreaks effectively, and the role of the US in the global health response.     (Source: The BMJ Podcast)
Source: The BMJ Podcast - December 1, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 1065: Cat coronavirus gains function in Cyprus
TWiV reviews ban on gain-of-function research by the House, chronic wasting disease in Tennessee deer, nOPV2 causing paralysis in children, and an outbreak of feline infectious peritonitis in Cyprus caused by a new recombinant coronavirus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Di...
Source: This Week in Virology - MP3 Edition - November 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1064: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses progress toward measles elimination, risk of severe coronavirus disease 2019 despite vaccination in patients requiring treatment with immune-suppressive drugs, symptoms, viral loads, and rebound among COVID-19 outpatients treated with nirmatrelvir/ritonavir compared to propensity score matched untreated individuals, late administration and corticosteroid usage explain inefficacy in COVID-19 convalescent plasma trial, higher-dose fluvoxamine and time to sustained recovery in outpatients with COVID-19, recombinant C1 inhibitor in the prevention of severe COVID-19, and Epst...
Source: This Week in Virology - MP3 Edition - November 25, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1062: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten, seasonality of endemic COVID-19, mRNA SARS-CoV-2 vaccination before vs during pregnancy and omicron infection among infants, extracting symptoms from free-text responses using ChatGPT among COVID-19 cases in Hong Kong, SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy, optimization of antiviral therapy in immunocompromised COVID-19 patients, a study to learn about the study medicines (nirmatrelvir plus ritonavir) in people aged 12 years or older...
Source: This Week in Virology - MP3 Edition - November 18, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Vitamin C for COVID-19, Stool Test for Colorectal Cancer Screening, USPSTF on Oral Health, and more
Editor’s Summary by Anthony Charles, MD, MPH, Associate Editor of JAMA, the Journal of the American Medical Association, for the November 14, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - November 14, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 1061: Seasonal COVID and a niche for cervical cancer
TWiV reveals a prediction of the expected endemic seasonality of COVID-19, based on circulation of human coronaviruses, and ecological clearance of vaccine-targeted human papillomaviruses and an increase in circulation of non-targeted virus types. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommi...
Source: This Week in Virology - MP3 Edition - November 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1060: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses CDC expanding testing of international air traveler samples to include flu, RSV, and other respiratory viruses, missed opportunities for preventing congenital syphilis, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and omicron BA.2 variant in Hong Kong, T-cell immunity against severe acute respiratory syndrome coronavirus 2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with delta or omicron variants, masks during pandemics caused by respiratory pathogens, ...
Source: This Week in Virology - MP3 Edition - November 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1058: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - November 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1056: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - October 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

How can we communicate better with people and communities about measures which help to prevent and control COVID-19?
Clear communication with the public is a key part of the response to disasters and health emergencies, and the October 2023 update of a rapid review from 2020 investigates this in relation to measures to help to prevent and control COVID-19. Here ' s lead author Rebecca Ryan from La Trobe University in Australia to tell us more. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - October 23, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts