TWiV 1040: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the public health significance of finding autochthonous melioidosis cases in the continental United States, human neural larva migrans caused by Ophidascaris robertsi ascarid, Project nextgen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics, excess all-cause mortality in China after ending the zero COVID policy, international pediatric COVID-19 severity over the course of the pandemic, differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination, Pfizer and BioNTech ...
Source: This Week in Virology - MP3 Edition - September 2, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1038: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses modeling poliovirus transmission and responses in New York State, FDA approves first vaccine for pregnant individuals to prevent RSV in infants, prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure, incidence of new-onset hypertension post–COVID-19: comparison with influenza, and post-acute sequel...
Source: This Week in Virology - MP3 Edition - August 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1037: Antibodies, the good (CoV), the bad (Ad), the beautiful
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Link...
Source: This Week in Virology - MP3 Edition - August 20, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1036: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the developme...
Source: This Week in Virology - MP3 Edition - August 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
JAMA Surgery : Outcomes Following Lung Transplant for COVID-19 –Related Complications in the US
Interview with Leonard J. Lobo, MD, and Jason M. Long, MD, MPH, authors of Outcomes Following Lung Transplant for COVID-19–Related Complications in the US. Hosted by Amalia Cochran, MD. Related Content: Outcomes Following Lung Transplant for COVID-19–Related Complications in the US (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - August 16, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
TWiV 1035: Poxvirus wars, warp speed COVID-19 vaccine rollout
TWiV dissects a study of COVID-19 vaccination which shows that the timing of initial rollout affects disease outcomes more substantially than final coverage or degree of socioeconomic disparity, and discovery of a novel cellular defense comprising a nuclease that is activated by poxvirus infection and cleaves a specific tRNA molecule to inhibit protein synthesis. Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant ...
Source: This Week in Virology - MP3 Edition - August 13, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1034: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the immunogenicity, safety, and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate, association between nose picking and SARS-CoV-2 incidence, a cohort study in hospital health care workers; effect of COVID-19 vaccination and booster on maternal-fetal outcomes, dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA, does monoclonal antibody treatment for COVID-19 impact short and long- term outcomes in a large generalizable population, persistent endothelial dysfunction in post-...
Source: This Week in Virology - MP3 Edition - August 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1033: Freediving with nanobodies and interferon
TWiV notes the passing of Harald zur Hausen, dengue breaking records in the Americas, inhibition of SARS-CoV-2 infection and inflammation by modulation of type I IFN, and an armed nanobody that protects mice against influenza A and B disease. Hosts: Vincent Racaniello, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Position in Rosenfeld Laboratory (pdf) Paul and the Mosquitos (pdf, English) Other childrens books (SMVIROLOGIA) Dengue breaking records in Amer...
Source: This Week in Virology - MP3 Edition - August 6, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1032: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses predicting COVID-19 incidence using wastewater surveillance data, use of wastewater metrics to track COVID-19 in the US, wastewater-based epidemiology predicts COVID-19-induced weekly new hospital admissions in over 150 USA counties, association between duration of SARS-CoV-2 positivity and long COVID, rapid direct detection of SARS-CoV-2 aerosols in exhaled breath at the point of care, effectiveness of oral Nirmatrelvir/Ritonavir vs. intravenous three-day Remdesivir in preventing progression to severe COVID-19, NIH launching of several phase 2 long-COVID treatment trial...
Source: This Week in Virology - MP3 Edition - August 5, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1031: Death on the West Nile
TWiV notes the passing of virologist Michael BA Oldstone, a study to assess the performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 infection, and the presence of antibodies to type I interferons in ~40% of patients with West Nile virus encephalitis. Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Position in Rosenfeld Laboratory (pdf) XKCD on antivaxxers RFK Jr. CDC or FDA head? (Politico) Performance of rapid...
Source: This Week in Virology - MP3 Edition - July 30, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 1030: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the use of RSV vaccines in older adults: recommendations of the advisory committee on immunization practices, case report of leprosy in Central Florida, blood group A enhances SARS-CoV-2 infection, predicting COVID-19 incidence using wastewater surveillance data, a common allele of HLA associated with asymptomatic SARS-CoV-2 infection, prevalence of low-frequency, antiviral resistance variants in SARS-CoV-2 isolates in Ontario, Canada, viral resistance analyses from the Remdesivir phase 3 adaptive COVID-19 treatment trial-1, impact of Molnupiravir treatment on patient-r...
Source: This Week in Virology - MP3 Edition - July 29, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts
AI-enhanced night-vision lets users see in the dark
In this episode:00:46 How to see in the dark like it’s daytimeThere are many methods for better night-vision, but often these rely on enhancing light, which may not be present, or using devices which can interfere with one another. One alternative solution is to use heat, but such infrared sensors struggle to distinguish between different objects. To overcome this, researchers have now combined such sensors with machine learning algorithms to make a system that grants day-like night-vision. They hope it will be useful in technologies such as self-driving cars.Research article: Bao et al.News and Views: Heat-assisted imag...
Source: Nature Podcast - July 26, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Immunomodulators for COVID-19, Pessary and Preterm Birth, Antibiotics for Sinusitis in Children, and more
Editor’s Summary by Preeti N. Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for the July 25, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - July 25, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
TWiV 1027: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the transmission of SARS-CoV-2 in free-ranging white-tailed deer in the United States, Omicron subvariant BA.5 efficiently infects lung cells, COVID-19 scent dog research highlights and synthesis during the pandemic of December 2019, T-Cell Immunity against SARS-CoV-2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with Delta or Omicron variants, a common allele of HLA is associated with asymptomatic SARS-CoV-2 infection, and the immunology of long COVID. Subscribe (free): Apple Podcasts, Googl...
Source: This Week in Virology - MP3 Edition - July 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
SCCM Pod-485: Better Together: The Power of Collaboration
The power of scientific collaboration has a broad reach. During the COVID-19 pandemic, more than 7000 clinical trials were registered, with more than 100 different countries represented. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, was joined by SCCM Lifetime Achievement Award Recipient John C. Marshall, MD, FRCSC, FACS, at the 2023 Critical Care Congress to discuss the importance of research and scientific collaboration. Dr. Marshall has been involved in research programs with researchers around the globe and is a well-known speaker with nearly 600 published manuscripts. This podcast is sponsored by Dompe Pharmaceutical....
Source: SCCM PodCast - iCritical Care - July 20, 2023 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
