TWiV 922: TWiV clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses monkeypox infection in humans across 16 countries, pregnancy outcomes after SARS-CoV-2 infection by trimester, vaccination intent and belief, antiviral drug treatment for non-severe disease, the association of smoking with infected hospitalized patients, the association of Paxlovid on negative conversion rates among high-risk patients with COVID-19, safety and efficacy of Molnupiravir, usage of enoxaparin for primary thromboprophylaxis, statin and aspirin as therapy in infected patients, post-COVID-19 conditions among children 90 days after SARS-CoV-2 Infection, and sympt...
Source: This Week in Virology - MP3 Edition - July 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: the open-science plan to unseat big Pharma and tackle vaccine inequity
Inequity has been a central feature of the COVID19 pandemic. From health outcomes to access to vaccines, COVID has pushed long-standing disparities out of the shadows and into the public eye and many of these problems are global. In this episode of Coronapod we dig into a radical new collaboration of 15 countries - led by the UN, and modelled on open-science. The project, called the mRNA vaccine technology transfer hub, aims to create independent vaccine hubs that could supply the global south, and take on the giants of the pharmaceutical industry in the process. But the road ahead is long - the challenges are co...
Source: Nature Podcast - July 29, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Tranexamic Acid in Cardiac Surgery, Aflibercept for Retinopathy of Prematurity, Income and Life Expectancy During the COVID-19 Pandemic, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the July 26, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - July 26, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 921: COVID-19 clinical update #124 with Dr. Daniel Griffin
In COVID-19 clinical update #124, Dr. Griffin discusses the results of a variant vaccine booster trial, the neutralization of variant sub-lineages by Novavax, the CDC’s recommendation of Novavax’s COVID-19 vaccine in adults, Paxlovid in patients who are immunocompromised and hospitalized, and inhaled fluticasone for outpatient treatment. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Variant vaccine boosters trial (medRxiv) Novavax triggers neutralization of variant sub-lineages (bioRxiv) CDC recommends Novavax (CDC) Paxlovid in patients who ar...
Source: This Week in Virology - MP3 Edition - July 23, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 919: Motivated by volatiles
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 vaccine booster composition (FDA) Settling in for the long haul (Crooked Timber) Flavivirus-induced skin volatile attracts mosquitoes (Cell) Letters read on TWiV 919 Timestamps by Jolene. Thanks! ...
Source: This Week in Virology - MP3 Edition - July 17, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin
In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of m...
Source: This Week in Virology - MP3 Edition - July 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The Webb Space Telescope ’s first images, and why scratching sometimes makes you itchy
On this week’s show: The first images from the James Webb Space Telescope hint at the science to come, and disentangling the itch-scratch cycle After years of delays, the James Webb Space Telescope launched at the end of December 2021. Now, NASA has released a few of the first full-color images captured by the instrument’s enormous mirror. Staff Writer Daniel Clery joins host Sarah Crespi to discuss these first images and what they mean for the future of science from Webb. Next on the podcast, Jing Feng, principal investigator at the Center for Neurological and Psychiatric Research and Drug Discovery at the Chinese A...
Source: Science Magazine Podcast - July 14, 2022 Category: Science Authors: Science Magazine Source Type: podcasts

The Webb Space Telescope ’s first images, and why scratching sometimes makes you itchy
On this week’s show: The first images from the James Webb Space Telescope hint at the science to come, and disentangling the itch-scratch cycle After years of delays, the James Webb Space Telescope launched at the end of December 2021. Now, NASA has released a few of the first full-color images captured by the instrument’s enormous mirror. Staff Writer Daniel Clery joins host Sarah Crespi to discuss these first images and what they mean for the future of science from Webb. Next on the podcast, Jing Feng, principal investigator at the Center for Neurological and Psychiatric Research and Drug Discovery at the Chinese A...
Source: Science Magazine Podcast - July 14, 2022 Category: Science Authors: Science Magazine Source Type: podcasts

Progress in Adverse Event Rates in US Hospitalized Patients
Patient safety is a national priority, but adverse events during hospitalization are hard to track and whether progress has been made over the past decade is unknown. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, Washington University School of Medicine, discusses recent findings demonstrating decreases in hospital chart-abstracted adverse events and what’s next in patient safety in the wake of COVID-19, with Mark Metersky, MD, University of Connecticut Health Center, and Peter Pronovost, MD, PhD, University Hospitals, Shaker Heights, Ohio. Related Content: Trends in Adverse Event Rates in Hospitalized Patients,...
Source: JAMA Author Interviews - July 12, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 917: Boosters on, Paul Offit
Paul Offit returns to TWiV to discuss why, during the recent FDA advisory committee meeting, he voted against releasing revised COVID-19 vaccines containing an Omicron component, and the reasons why children must be vaccinated against the disease. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 28 June 2022 VRBPAC meeting materials (FDA) Don’t rush to change COVID vaccines (STAT) Materials from 28 June FDA advisory meeting (FDA) Letters read on TWiV 917 Tim...
Source: This Week in Virology - MP3 Edition - July 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin
In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation ca...
Source: This Week in Virology - MP3 Edition - July 9, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

JAMA Oncology : Global Association of COVID-19 Pandemic Measures With Cancer Screening
Interview with Paolo Boffetta, MD, author of Global Association of COVID-19 Pandemic Measures With Cancer Screening: A Systematic Review and Meta-analysis. Hosted by Jack West, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - July 7, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

How accurate is chest imaging for diagnosing COVID-19?
The Cochrane programme of reviews for COVID-19 covers both the diagnosis and treatment of the disease and reviews are being updated as new evidence becomes available. Among these is a review of chest imaging for diagnosing the condition, and its fourth version was published in May 2022. We asked the lead author, Sanam Ebrahimzadeh, from The Ottawa Hospital Research Institute in Canada, to describe the latest findings in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - July 4, 2022 Category: General Medicine Authors: Cochrane Source Type: podcasts

TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin
In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Age as a risk factor for severe disease (NY Times) Omicron boosters for the fall (NPR) P...
Source: This Week in Virology - MP3 Edition - July 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin
In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Reinfection outcomes (Research Square) CDC recommends v...
Source: This Week in Virology - MP3 Edition - June 25, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts