COVID-19 ’s long-term impact on the heart, and calculating the survival rate of human artifacts
On this week’s show: A giant study suggests COVID-19 takes a serious toll on heart health—a full year after recovery, and figuring out what percentage of ancient art, books, and even tools has survived the centuries  First up, Staff Writer Meredith Wadman talks with host Sarah Crespi about a new study that looked at more than 150,000 COVID-19 patient records and found increases in risk for 20 different cardiovascular conditions 1 year after recovery. Also this week we have Mike Kestemont, an associate professor in the department of literature at the University of Antwerp, talking about an estimate of how much of ant...
Source: Science Magazine Podcast - February 17, 2022 Category: Science Authors: Science Magazine Source Type: podcasts

Prevention of Self-harm in Adults With Suicidal Ideation, Symptomatic Omicron and Delta SARS-CoV-2 Infection Following Vaccination, Outcomes of Lung Transplant for COVID-19 ARDS, and more
Editor's Summary by Preeti Malani, MD, Associate Editor of JAMA, the Journal of the American Medical Association, for the February 15, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - February 15, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 866: EV antibodies rEVolutionize our thinking
Amy returns to TWiV to discuss her work on the identification of cross-reactive antibody responses among diverse enteroviruses, and the implications for our understanding of viral pathogenesis and seroprevalence studies. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit Brianne Barker, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ABRCMS ePoster Spring Symposium for Emerging Scientists Cross-reactive enterovirus antibodies (mBio) Poliovirus receptor transgenic mice (virology blog) Timestamps by Jolene. Thanks! Weekly Picks Di...
Source: This Week in Virology - MP3 Edition - February 13, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 865: COVID-19 clinical update #101 with Dr. Daniel Griffin
In COVID-19 clinical update #101, Daniel Griffin discusses children and COVID, human challenge study results, effectiveness of mask use, Omicron boost in macaques, mucosal vaccine candidate, long-term cardiovascular outcomes, and global vaccine perceptions. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Children and COVID state data (AAP) Human challenge study (Res Sq) Effectiveness of mask use (MMWR) Omicron boost in macaques (bioRxiv) Mucosal vaccine candidate (Cell) Long-term cardiovascular outcomes (Nat Med) Global vaccine perceptions (PLoSNTD) Lette...
Source: This Week in Virology - MP3 Edition - February 12, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Subcutaneous Tirzepatide for Type 2 Diabetes, Noninvasive Respiratory Strategies for COVID-19 and Acute Hypoxemic Respiratory Failure, Clinical Outcomes 1 Year After ICU Treatment for COVID-19, and more
Editor's Summary by Gregory Curfman, MD, Deputy Editor of JAMA, the Journal of the American Medical Association, for the February 8, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - February 8, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 862: COVID-19 clinical update #100 with Dr. Daniel Griffin
In COVID-19 clinical update #100, Daniel Griffin, from Accra, Ghana, reviews the challenges in evaluating Omicron severity, over 800 deaths in children, Pfizer vaccine EUA application for under 5 year olds, false positives from soft drinks, Novavax vaccine EUA application, childhood experiences and vaccine hesitancy, fourth vaccine dose in Israel, effects of antivirals and monoclonals against Omicron, and multiple factors associated with PASC. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron severity challenges (NEJM) Children and COVID data (AAP) ...
Source: This Week in Virology - MP3 Edition - February 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: what people get wrong about endemic COVID
The word endemic is often mistakenly used to describe a rosy end to the pandemic where COVID-19 becomes a mild, but ever-present infection akin to the common cold. But this is by no means guaranteed and the reality could be much less favourable. In this episode of Coronapod we get the evolutionary virologist's take - asking what endemicity might really look like, and what control we still have in shaping the future of SARS-CoV-2.World View: COVID-19: endemic doesn’t mean harmlessSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every w...
Source: Nature Podcast - February 4, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: what people get wrong about endemic COVID
The word endemic is often mistakenly used to describe a rosy end to the pandemic where COVID-19 becomes a mild, but ever-present infection akin to the common cold. But this is by no means guaranteed and the reality could be much less favourable. In this episode of Coronapod we get the evolutionary virologist's take - asking what endemicity might really look like, and what control we still have in shaping the future of SARS-CoV-2.World View: COVID-19: endemic doesn’t mean harmlessSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every w...
Source: Nature Podcast - February 4, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

February 2022: Palliative Care in the ED, COVID-19 in Children, and the ACEP Opioid Policy
Amal Mattu, MD, and colleagues explore some serious topics in this month’s podcast. (Source: Emergency Medicine News: SoundsBites: Q&A)
Source: Emergency Medicine News: SoundsBites: Q&A - January 31, 2022 Category: Emergency Medicine Source Type: podcasts

TWiV 860: Evading a Toll on the road to RNA vaccines
TWiV reviews a seminal paper showing that chemically modified bases in RNAs suppress recognition by Toll-like receptors, a finding that that was essential for the development of COVID-19 mRNA vaccines. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine Town Hall (ASV) Columbia University BSL-3 Manager position RNA modifications suppress innate recognition (Immunity) Critical contribution of pseudouridine (Front Cell Dev Biol) Rich Condit reminisces (YouTube) Letters read ...
Source: This Week in Virology - MP3 Edition - January 30, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 859: COVID-19 clinical update #99 with Dr. Daniel Griffin
In COVID-19 clinical update #99, Daniel Griffin discusses Omicron disease severity, neurologic manifestations in children, testing outcomes during multiple infections, boosters improve VE and VD, booster efficacy for ED and UC encounters, vaccines induce cross-protective T cell memory, and indications for monoclonal antibody therapy.C Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron disease severity (MMWR) Neurologic manifestations in children (Pediatric Neurol) Respiratory virus interference (Emerg Inf Dis) Hospitalization by vaccination status (C...
Source: This Week in Virology - MP3 Edition - January 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 858: The vax of life with John Mascola
John Mascola joins TWiV to discuss the history and mission of the NIH Vaccine Research Center, how it prepared for devising pandemic vaccines, and development of the COVID-19 vaccines. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Guest: John Mascola Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Accelerated COVID-19 vaccine development (Immunity) Letters read on TWiV 858 Timestamps by Jolene. Thanks! Weekly Picks Brianne – How Sesame Street is Handling the Pandemic Rich – Zamboni: How it works Alan – How lightning starts V...
Source: This Week in Virology - MP3 Edition - January 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: Why T cells have been overlooked
Much of the coverage of COVID immunity often focuses on antibody response and for good reason - these small, y-shaped proteins can detect, and in some cases neutralise, viruses like SARS-CoV-2. But as variants like Omicron evolve to evade antibodies, the role of another part of the immune system, T cells, has been brought into sharper focus. These immune cells work in a different way to antibodies, attacking infected cells rather than the virus itself, which can make their response broader and more robust. Now, research is showing that, unlike antibodies, T cell potency is not impacted by the mutations in variants like Omi...
Source: Nature Podcast - January 28, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: Why T cells have been overlooked
Much of the coverage of COVID immunity often focuses on antibody response and for good reason - these small, y-shaped proteins can detect, and in some cases neutralise, viruses like SARS-CoV-2. But as variants like Omicron evolve to evade antibodies, the role of another part of the immune system, T cells, has been brought into sharper focus. These immune cells work in a different way to antibodies, attacking infected cells rather than the virus itself, which can make their response broader and more robust. Now, research is showing that, unlike antibodies, T cell potency is not impacted by the mutations in variants like Omi...
Source: Nature Podcast - January 28, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Talk Evidence - isolation periods, openness, and environmental impacts
In the first Talk Evidence of 2022, we'll be asking about the evidence for isolation - now that isolation periods are being reduced, or even stopped in the event of a negative lateral flow test, we'll find out what data that's based on, and if it's appropriate. Vaccinations and treatments for covid-19 have been the one major success story of the pandemic, but that doesn't mean we should abandon the principles of openness and transparency when it comes to scrutinising the data - we'll hear what access to the data which underlies regulatory approval could do now. Finally, the impacts of climate change were set out in a WH...
Source: The BMJ Podcast - January 28, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts