TWiV 978: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the Omicron variant and severe disease, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe dis...
Source: This Week in Virology - MP3 Edition - January 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Talk Evidence - excess deaths, the ONS, and the healthcare crisis
In this week's episode, we're focusing on covid and the ongoing crisis in the NHS.
Helen Macdonald, Juan Franco and Joseph Ross cast their evidence seeking eyes over research into outcomes as well as the workload of doctors.
Firstly, Joe tells us about a new big data study into longer term outcomes after mild covid-19, how those ongoing symptoms relate to long covid, and how often they resolve themselves.
Juan looks back to his homeland to see what Argentina which was very early to offer children vaccinations against covid-19. He tells us how a new study design can help understand how effective different combinations of...
Source: The BMJ Podcast - January 27, 2023 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts
Talk Evidence - excess deaths, the ONS, and the healthcare crisis
In this week's episode, we're focusing on covid and the ongoing crisis in the NHS.
Helen Macdonald, Juan Franco and Joseph Ross cast their evidence seeking eyes over research into outcomes as well as the workload of doctors.
Firstly, Joe tells us about a new big data study into longer term outcomes after mild covid-19, how those ongoing symptoms relate to long covid, and how often they resolve themselves.
Juan looks back to his homeland to see what Argentina which was very early to offer children vaccinations against covid-19. He tells us how a new study design can help understand how effective different combinations of...
Source: The BMJ Podcast - January 27, 2023 Category: General Medicine Authors: BMJ Group Source Type: podcasts
Fluvoxamine for Outpatients With Mild to Moderate COVID-19, Accuracy of Stroke Risk Prediction Models, Organization and Performance of US Health Systems, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the January 24/31, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - January 24, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
TWiV 977: Ageing is infectious
TWiV covers a study of SARS-CoV-2 persistence at multiple sites in the human body, and the role of endogenous retroviruses in ageing and senescence. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Persistence of SARS-CoV-2 (Nature) •Endogenous retroviruses and senescence (Cell) •Timestamps by Jolene. Thanks! Weekly Picks Dickson – Baritone Saxoph...
Source: This Week in Virology - MP3 Edition - January 22, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 976: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently inves...
Source: This Week in Virology - MP3 Edition - January 21, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 974: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses poliovirus returns to New York wastewater, COVID-19 is more widespread in animals than we thought, increasing ventilation reduces SARS-CoV-2 airborne transmission in schools, the use of carbon dioxide monitoring to assess ventilation at a national infectious diseases conference, effectiveness of the bivalent mRNA vaccine in preventing severe COVID-19 outcomes, 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection, and long COVID outcomes at one year after mild SARS-CoV-2 infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS...
Source: This Week in Virology - MP3 Edition - January 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Fluvoxamine vs Placebo and Time to Sustained Recovery From Mild or Moderate COVID-19
Susanna Naggie, MD, vice dean for research at Duke University's School of Medicine, discusses the ACTIV-6 trial of fluvoxamine for outpatient treatment of COVID-19 and outlines the role of platform trials during the pandemic. Hosted by JAMA Deputy Editor and Editorial Director for Equity Preeti Malani, MD, MSJ. Related Content: Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19 (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - January 12, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
TWiV 972: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans, time to negative PCR conversion among high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated by Sotrovimab or Nirmatrelvir, COVID drug Paxlovid was hailed as a game-changer,...
Source: This Week in Virology - MP3 Edition - January 7, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Rapid-Onset Opioid vs Neuromuscular Blocker for Rapid Sequence Intubation, 180-Day Outcomes in COVID-19 in REMAP-CAP, Recommendations for Antiretrovirals for Treatment and Prevention of HIV, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the January 3, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - January 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
Urgent Need for Next-Generation COVID-19 Vaccines
JAMA Deputy Editor Preeti Malani, MD, MSJ, discusses potential next-generation COVID-19 vaccines with Peter Marks, MD, PhD, director of the Center for Biologics Evaluation and Research at the US Food and Drug Administration. Related Content: Urgent Need for Next-Generation COVID-19 Vaccines (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - January 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
TWiV 970: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses modelling the adjustment of COVID-19 response and exit from dynamic zero-COVID in China, canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event, two masks can be worse than one: N95 respirator failure caused by an overlying face mask, airflow patterns in double-occupancy patient rooms may contribute to roommate-to-roommate transmission of severe SARS-CoV-2, clinical validation of a novel T-Cell receptor sequencing assay for identification of recent or prior SARS-CoV-2 infection, antibody-dependent cellular cytotoxicity against SARS-...
Source: This Week in Virology - MP3 Edition - December 31, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 969: Carl Zimmer on COVID-19
Carl Zimmer visits the Incubator to record a wide-ranging conversation about COVID-19, including origins, vaccines, public health responses, and impact on society. Host: Vincent Racaniello Guest: Carl Zimmer Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - December 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
SCCM Pod-468: When Should Antibiotics Be Used to Treat Respiratory Infections?
Although only a small number of patients hospitalized with COVID-19 present with a secondary bacterial pneumonia, a large percentage are unnecessarily treated with antibiotics. Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by George Sakoulas, MD, to discuss how physicians and hospitalists can identify when antibiotics are unnecessary for hospitalized patients with moderate to severe respiratory infections. Dr. Sakoulas is chief of infectious disease at Sharp Rees-Stealy Medical Group in San Diego, California, and an adjunct professor in the Division of Host-Microbe Systems and Therapeutics Center for Immunity, Infection...
Source: SCCM PodCast - iCritical Care - December 27, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
SCCM Pod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - December 21, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts
