TWiV 947: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt at Vaccinated.US Prediction of upcoming global infection burden...
Source: This Week in Virology - MP3 Edition - October 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 945: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health measures, tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine, clinical, virologic, and immunologic evaluation of symptomatic rebound following Nirmatrelvir/Ritonavir treatment, early outpatient treatment with Eemdesivir in patients at high risk for severe COVID-19, Molnupiravir plus usual care versus usual care alone as early treatme...
Source: This Week in Virology - MP3 Edition - October 15, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Inquiring about covid, burnout, and marginal data
It's October's Talk Evidence, and that means the autumn is upon us including those autumnal viruses. Here in the UK covid is on the rise, and Joe Ross is looking at some research on how good those elusive lateral flows are at detecting infection among people with symptoms of covid. Juan will give us an update on the covid inquiry, the collection of analysis articles The BMJ is publishing looking at the interface of evidence and policy in our decisions about how to handle the pandemic. Since the pandemic moral among clinicians in many health systems has fallen even further, workloads have spiralled. Coupled with other pro...
Source: The BMJ Podcast - October 12, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence - Inquiring about covid, burnout, and marginal data
It's October's Talk Evidence, and that means the autumn is upon us including those autumnal viruses. Here in the UK covid is on the rise, and Joe Ross is looking at some research on how good those elusive lateral flows are at detecting infection among people with symptoms of covid. Juan will give us an update on the covid inquiry, the collection of analysis articles The BMJ is publishing looking at the interface of evidence and policy in our decisions about how to handle the pandemic. Since the pandemic moral among clinicians in many health systems has fallen even further, workloads have spiralled. Coupled with other pro...
Source: The BMJ Podcast - October 12, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence - Inquiring about covid, burnout, and marginal data
It's October's Talk Evidence, and that means the autumn is upon us including those autumnal viruses. Here in the UK covid is on the rise, and Joe Ross is looking at some research on how good those elusive lateral flows are at detecting infection among people with symptoms of covid. Juan will give us an update on the covid inquiry, the collection of analysis articles The BMJ is publishing looking at the interface of evidence and policy in our decisions about how to handle the pandemic. Since the pandemic moral among clinicians in many health systems has fallen even further, workloads have spiralled. Coupled with other pro...
Source: The BMJ Podcast - October 12, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Paroxetine vs Quetiapine and Hypercapnia, SARS-CoV-2 Vaccination and COVID-19 Outcomes, USPSTF Recommendation on Anxiety in Children and Adolescents, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the October 11, 2022, issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - October 11, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 943: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses high points of the multi-national monkeypox outbreaks, monkeypox virus genome mutations, possible occupational infection of healthcare workers with monkeypox virus, rates of monkeypox cases by vaccination status, protection of SARS-CoV-2 infection against reinfection, Paxlovid significantly reduces COVID-19 hospitalizations and deaths, and rebound in COVID19 with and without Paxlovid treatment. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position with Amy Rosenfeld (pdf) Support M...
Source: This Week in Virology - MP3 Edition - October 8, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Anthony Fauci on COVID-19, scientific communication, and the future
Dr. Anthony Fauci, Chief Medical Advisor to the President of the United States and Director of NIAID, is standing down at the end of 2022. He joins Gavin and Jessamy to discuss becoming a household name during the COVID-19 pandemic, why scientific discourse in the USA is broken, and how the pandemic could end. (Source: Listen to The Lancet)
Source: Listen to The Lancet - October 7, 2022 Category: General Medicine Authors: The Lancet Source Type: podcasts

SCCMPod-463 CCM: Clazakizumab for COVID-19: Friend or Foe?
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials of clazakizumab for treatment of COVID-19 are under way worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation, published in the September 2022 issue of Critical Care Medicine. Dr. Lonze is a faculty transplant sur...
Source: SCCM PodCast - iCritical Care - October 6, 2022 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 942: Omicron boosters with Paul Offit
Paul Offit returns to TWiV for a discussion of SARS-CoV-2 bivalent boosters containing ancestral and Omicron spike mRNAs, including their composition, why they are being recommended by CDC, and who would benefit the most from them. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit,  Kathy Spindler, and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) CDC oversells bivalent booster (Wall St Journal) FDA authorizes biva...
Source: This Week in Virology - MP3 Edition - October 2, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 941: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses increased acute respiratory illnesses among children and adolescents, estimates of monkeypox incubation period, generation time, and reproduction number, rapid increase in suspected SARS-CoV-2 reinfections, interim infection prevention and control recommendations for healthcare personnel during COVID-19, SARS-CoV-2 secondary attack rates in vaccinated and unvaccinated household contacts during replacement of delta with omicron variant, breakthrough infection by SARS-CoV-2 delta and omicron variants elicited immune response comparable to mRNA booster vaccination, inter...
Source: This Week in Virology - MP3 Edition - October 1, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Audio long read: What scientists have learnt from COVID lockdowns
Conclusions suggest that countries that acted swiftly to bring in strict measures did best at preserving lives and their economies, but analysing the competing costs and benefits of lockdowns has been tough, as this work often comes down not to scientific calculations, but value judgements.This is an audio version of our Feature: What scientists have learnt from COVID lockdowns Hosted on Acast. See acast.com/privacy for more information. (Source: Nature Podcast)
Source: Nature Podcast - September 30, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 940: Eddie Holmes in on viral origins
Eddie Holmes joins TWiV to discuss his role in the first release of the SARS-CoV-2 genome sequence, what really happened during the infamous Fauci teleconference, and evidence that the virus came from Nature and not from a lab. Hosts: Vincent Racaniello and Dickson Despommier Guest: Eddie Holmes Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Novel 2019 coronavirus genome (Virological) Proximal origins of SARS-CoV-2 (Virological and Nature versions) Original p...
Source: This Week in Virology - MP3 Edition - September 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 938: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b2 against Omicron, awareness and use of SARS-CoV-2 antivirals, comparable outcomes for Bebtelovimab and Nirmatrelvir, and COVID-19 and Alzheimer's disease. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a...
Source: This Week in Virology - MP3 Edition - September 24, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts