Organization and replicon interactions within the highly segmented genome of < i > Borrelia burgdorferi < /i >
by Zhongqing Ren, Constantin N. Takacs, Hugo B. Brand ão, Christine Jacobs-Wagner, Xindan WangBorrelia burgdorferi, a causative agent of Lyme disease, contains the most segmented bacterial genome known to date, with one linear chromosome and over twenty plasmids. How this unusually complex genome is organized, and whether and how the different replicons interact are unclear. We recently demonstrated thatB.burgdorferi is polyploid and that the copies of the chromosome and plasmids are regularly spaced in each cell, which is critical for faithful segregation of the genome to daughter cells. Regular spacing of the chromosome...
Source: PLoS Genetics - July 26, 2023 Category: Genetics & Stem Cells Authors: Zhongqing Ren Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Soft Tick Relapsing Fever - United States, 2012-2021
This report summarizes demographic and clinical information for STRF cases reported during 2012-2021 from states where STRF is reportable. During this period, 251 cases were identified in 11 states. The median annual case count was 24. Most patients with STRF (55%) were hospitalized; no fatalities were reported. The geographic distribution and seasonal pattern of STRF have remained relatively constant since the 1990s. Persons should avoid rodent-infested structures and rodent habitats, such as caves, in areas where STRF is endemic. STRF surveillance, prevention, and control efforts would benefit from a standardized case de...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Amy M Beeson Anne Kjemtrup Hanna Oltean Hannah Schnitzler Heather Venkat Irene Ruberto Natalie Marzec Devon Cozart Leslie Tengelsen Stephen Ladd-Wilson Hannah Rettler Bonny Mayes Kelly Broussard Ali Garcia Lisa L Drake Elizabeth A Dietrich Jeannine Peters Source Type: research
Snakes and Souks: Zoonotic pathogens associated to reptiles in the Marrakech markets, Morocco
by Jairo Alfonso Mendoza-Roldan, Viviane Noll Louzada-Flores, Nouha Lekouch, Intissar Khouchfi, Giada Annoscia, Andrea Zatelli, Fr édéric Beugnet, Julia Walochnik, Domenico Otranto
The world-famous markets of Marrakech, also known in Arabic as souks, harbor a vast diversity of reptiles that are sold for medicinal/magic/pet purposes or used for snake charming. This unique epidemiological context has never been studied considering the interactions of humans, reptiles, and zoonotic pathogens. Thus, the aim of this study was to identify the parasites and pathogens present in blood and feces associated with handled reptiles ...
Source: PLoS Neglected Tropical Diseases - July 19, 2023 Category: Tropical Medicine Authors: Jairo Alfonso Mendoza-Roldan Source Type: research
A high fidelity approach to assembling the complex Borrelia genome
Bacteria of the Borrelia burgdorferi sensu lato (s.l.) complex can cause Lyme borreliosis. Different B. burgdorferi s.l. genospecies vary in their host and vector associations and human pathogenicity but the gene... (Source: BMC Genomics)
Source: BMC Genomics - July 17, 2023 Category: Genetics & Stem Cells Authors: Sabrina Hepner, Konstantin Kuleshov, Ave Tooming-Kunderud, Nikolas Alig, Alexander Gofton, Sherwood Casjens, Robert E. Rollins, Alexandra Dangel, Evangelos Mourkas, Samuel K. Sheppard, Andreas Wieser, Johannes H übner, Andreas Sing, Volker Fingerle and G Tags: Research Source Type: research
Evidence of protozoan and bacterial infection and co-infection and partial blood feeding in the invasive tick haemaphysalis longicornis in pennsylvania
J Parasitol. 2023 Jul 1;109(4):265-273. doi: 10.1645/22-122.ABSTRACTThe Asian longhorned tick, Haemaphysalis longicornis, an invasive tick species in the United States, has been found actively host-seeking while infected with several human pathogens. Recent work has recovered large numbers of partially engorged, host-seeking H. longicornis, which together with infection findings raises the question of whether such ticks can reattach to a host and transmit pathogens while taking additional bloodmeals. Here we conducted molecular blood meal analysis in tandem with pathogen screening of partially engorged, host-seeking H. lon...
Source: The Journal of Parasitology - July 12, 2023 Category: Parasitology Authors: Keith J Price Noelle Khalil Bryn J Witmier Brooke L Coder Christian N Boyer Erik Foster Rebecca J Eisen Goudarz Molaei Source Type: research
Evidence of protozoan and bacterial infection and co-infection and partial blood feeding in the invasive tick haemaphysalis longicornis in pennsylvania
J Parasitol. 2023 Jul 1;109(4):265-273. doi: 10.1645/22-122.ABSTRACTThe Asian longhorned tick, Haemaphysalis longicornis, an invasive tick species in the United States, has been found actively host-seeking while infected with several human pathogens. Recent work has recovered large numbers of partially engorged, host-seeking H. longicornis, which together with infection findings raises the question of whether such ticks can reattach to a host and transmit pathogens while taking additional bloodmeals. Here we conducted molecular blood meal analysis in tandem with pathogen screening of partially engorged, host-seeking H. lon...
Source: The Journal of Parasitology - July 12, 2023 Category: Parasitology Authors: Keith J Price Noelle Khalil Bryn J Witmier Brooke L Coder Christian N Boyer Erik Foster Rebecca J Eisen Goudarz Molaei Source Type: research
Evidence of protozoan and bacterial infection and co-infection and partial blood feeding in the invasive tick haemaphysalis longicornis in pennsylvania
J Parasitol. 2023 Jul 1;109(4):265-273. doi: 10.1645/22-122.ABSTRACTThe Asian longhorned tick, Haemaphysalis longicornis, an invasive tick species in the United States, has been found actively host-seeking while infected with several human pathogens. Recent work has recovered large numbers of partially engorged, host-seeking H. longicornis, which together with infection findings raises the question of whether such ticks can reattach to a host and transmit pathogens while taking additional bloodmeals. Here we conducted molecular blood meal analysis in tandem with pathogen screening of partially engorged, host-seeking H. lon...
Source: The Journal of Parasitology - July 12, 2023 Category: Parasitology Authors: Keith J Price Noelle Khalil Bryn J Witmier Brooke L Coder Christian N Boyer Erik Foster Rebecca J Eisen Goudarz Molaei Source Type: research
Evidence of protozoan and bacterial infection and co-infection and partial blood feeding in the invasive tick haemaphysalis longicornis in pennsylvania
J Parasitol. 2023 Jul 1;109(4):265-273. doi: 10.1645/22-122.ABSTRACTThe Asian longhorned tick, Haemaphysalis longicornis, an invasive tick species in the United States, has been found actively host-seeking while infected with several human pathogens. Recent work has recovered large numbers of partially engorged, host-seeking H. longicornis, which together with infection findings raises the question of whether such ticks can reattach to a host and transmit pathogens while taking additional bloodmeals. Here we conducted molecular blood meal analysis in tandem with pathogen screening of partially engorged, host-seeking H. lon...
Source: The Journal of Parasitology - July 12, 2023 Category: Parasitology Authors: Keith J Price Noelle Khalil Bryn J Witmier Brooke L Coder Christian N Boyer Erik Foster Rebecca J Eisen Goudarz Molaei Source Type: research
Evidence of protozoan and bacterial infection and co-infection and partial blood feeding in the invasive tick haemaphysalis longicornis in pennsylvania
J Parasitol. 2023 Jul 1;109(4):265-273. doi: 10.1645/22-122.ABSTRACTThe Asian longhorned tick, Haemaphysalis longicornis, an invasive tick species in the United States, has been found actively host-seeking while infected with several human pathogens. Recent work has recovered large numbers of partially engorged, host-seeking H. longicornis, which together with infection findings raises the question of whether such ticks can reattach to a host and transmit pathogens while taking additional bloodmeals. Here we conducted molecular blood meal analysis in tandem with pathogen screening of partially engorged, host-seeking H. lon...
Source: The Journal of Parasitology - July 12, 2023 Category: Parasitology Authors: Keith J Price Noelle Khalil Bryn J Witmier Brooke L Coder Christian N Boyer Erik Foster Rebecca J Eisen Goudarz Molaei Source Type: research
Detection of Bartonella DNA in Yellow Flies, Lone Star Ticks, and a Human Patient with Concurrent Evidence of Borrelia burgdorferi Infection in Northeast Florida, USA
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - July 10, 2023 Category: Infectious Diseases Authors: Kerry L. Clark Julissa Villegas Nunez Source Type: research
