GSE233658 Adiponectin in the mammalian host influences ticks' acquisition of the Lyme disease pathogen Borrelia
Contributors : Xiaotian Tang ; Erol FikrigSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo understand the global gene expression profile at the tick bite site of adiponectin wildtype and knockout mice (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - September 6, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

Characterisation and comparative genomics of three new Varanus-associated Borrelia spp. from Indonesia and Australia
Borrelia are important disease-causing tick- and louse-borne spirochaetes than can infect a wide variety of vertebrates, including humans and reptiles. Reptile-associated (REP) Borrelia, once considered a peculia... (Source: Parasites and Vectors)
Source: Parasites and Vectors - September 5, 2023 Category: Microbiology Authors: Alexander William Gofton, Angel Popa-Baez, Ai Takano, Kari Soennichsen, Michelle Michie, Makenna Short, Supriyono Supriyono, Jack Pascoe, Sue Cusbert and Robert Mulley Tags: Research Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | DOI:10.2807/1560-7917.ES.2023.28.34...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | PMC:PMC10451011 | DOI:10.2807/1560-...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | PMC:PMC10451011 | DOI:10.2807/1560-...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | PMC:PMC10451011 | DOI:10.2807/1560-...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | PMC:PMC10451011 | DOI:10.2807/1560-...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of < em > Borrelia burgdorferi- < /em > specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated.PMID:37616114 | PMC:PMC10451011 | DOI:10.2807/1560-...
Source: Euro Surveill - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm Tom Woudenberg Klaus Stark Merle M B öhmer Katharina Katz Ronny Kuhnert Martin Schlaud Hendrik Wilking Volker Fingerle Source Type: research

Seroprevalence, seroconversion and seroreversion of Borrelia burgdorferi-specific IgG antibodies in two population-based studies in children and adolescents, Germany, 2003 to 2006 and 2014 to 2017
ConclusionWe did not detect a change in seroprevalence in children and adolescents in Germany over a period of 11 years. Potential long-term changes, for example due to climatic changes, need to be assessed in consecutive serosurveys. Seroconversion was more likely among children and adolescents than among adults, representing a target group for preventive measures. Seroreversion rates are over twice as high in children and adolescents compared with previous studies among adults. Thus, seroprevalence estimates and seroconversion rates in children are likely underestimated. (Source: Eurosurveillance)
Source: Eurosurveillance - August 24, 2023 Category: Infectious Diseases Authors: Stefanie B öhm, Tom Woudenberg, Klaus Stark, Merle M Böhmer, Katharina Katz, Ronny Kuhnert, Martin Schlaud, Hendrik Wilking and Volker Fingerle Source Type: research

Characteristics of Hard Tick Relapsing Fever Caused by Borrelia miyamotoi, United States, 2013-2019
Emerg Infect Dis. 2023 Sep;29(9). doi: 10.3201/eid2909.221912.ABSTRACTBorrelia miyamotoi, transmitted by Ixodes spp. ticks, was recognized as an agent of hard tick relapsing fever in the United States in 2013. Nine state health departments in the Northeast and Midwest have conducted public health surveillance for this emerging condition by using a shared, working surveillance case definition. During 2013-2019, a total of 300 cases were identified through surveillance; 166 (55%) were classified as confirmed and 134 (45%) as possible. Median age of case-patients was 52 years (range 1-86 years); 52% were male. Most cases (70%...
Source: Emerging Infectious Diseases - August 23, 2023 Category: Infectious Diseases Authors: David W McCormick Catherine M Brown Jenna Bjork Kim Cervantes Brenda Esponda-Morrison Jason Garrett Natalie Kwit Abigail Mathewson Charles McGinnis Marco Notarangelo Rebecca Osborn Elizabeth Schiffman Haris Sohail Amy M Schwartz Alison F Hinckley Kiersten Source Type: research

Characteristics of Hard Tick Relapsing Fever Caused by Borrelia miyamotoi, United States, 2013-2019
Emerg Infect Dis. 2023 Sep;29(9). doi: 10.3201/eid2909.221912.ABSTRACTBorrelia miyamotoi, transmitted by Ixodes spp. ticks, was recognized as an agent of hard tick relapsing fever in the United States in 2013. Nine state health departments in the Northeast and Midwest have conducted public health surveillance for this emerging condition by using a shared, working surveillance case definition. During 2013-2019, a total of 300 cases were identified through surveillance; 166 (55%) were classified as confirmed and 134 (45%) as possible. Median age of case-patients was 52 years (range 1-86 years); 52% were male. Most cases (70%...
Source: Emerging Infectious Diseases - August 23, 2023 Category: Infectious Diseases Authors: David W McCormick Catherine M Brown Jenna Bjork Kim Cervantes Brenda Esponda-Morrison Jason Garrett Natalie Kwit Abigail Mathewson Charles McGinnis Marco Notarangelo Rebecca Osborn Elizabeth Schiffman Haris Sohail Amy M Schwartz Alison F Hinckley Kiersten Source Type: research

Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
CONCLUSION: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.PMID:37606856 | DOI:10.1007/s00262-023-03498-0 (Source: Cancer Control)
Source: Cancer Control - August 22, 2023 Category: Cancer & Oncology Authors: C Schmitt E P Hoefsmit T Fangmeier N Kramer C Kabakci J Vera Gonz ález J M Versluis A Compter T Harrer H Mijo čević S Schubert T Hundsberger A M Menzies R A Scolyer G V Long L E French C U Blank L M Heinzerling Source Type: research

Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
CONCLUSION: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.PMID:37606856 | DOI:10.1007/s00262-023-03498-0 (Source: Herpes)
Source: Herpes - August 22, 2023 Category: Infectious Diseases Authors: C Schmitt E P Hoefsmit T Fangmeier N Kramer C Kabakci J Vera Gonz ález J M Versluis A Compter T Harrer H Mijo čević S Schubert T Hundsberger A M Menzies R A Scolyer G V Long L E French C U Blank L M Heinzerling Source Type: research

Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
CONCLUSION: Previous viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.PMID:37606856 | DOI:10.1007/s00262-023-03498-0 (Source: Herpes)
Source: Herpes - August 22, 2023 Category: Infectious Diseases Authors: C Schmitt E P Hoefsmit T Fangmeier N Kramer C Kabakci J Vera Gonz ález J M Versluis A Compter T Harrer H Mijo čević S Schubert T Hundsberger A M Menzies R A Scolyer G V Long L E French C U Blank L M Heinzerling Source Type: research

Characteristics of Hard Tick Relapsing Fever Caused by Borrelia miyamotoi, United States, 2013 –2019
D. W. McCormick et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - August 18, 2023 Category: Infectious Diseases Source Type: research