Borrelia burgdorferi Infection-Induced Persistent IgM Secretion Controls Bacteremia, but Not Bacterial Dissemination or Tissue Burden
J Immunol. 2023 Oct 2:ji2300384. doi: 10.4049/jimmunol.2300384. Online ahead of print.ABSTRACTInfection with Borrelia burgdorferi causes Lyme disease in humans. In small rodents, the natural reservoir species of this spirochete, infections lead to only modest disease manifestations, despite causing persistence infection. Although B cell responses are central for controlling bacterial tissue burden and disease manifestations, they lack classical aspects of T-dependent responses, such as sustained IgG affinity maturation and longevity, corresponding with a rapid collapse of germinal centers. Instead, the Ab response is chara...
Source: Journal of Immunology - October 2, 2023 Category: Allergy & Immunology Authors: Christine J Hastey Kimberly J Olsen Rebecca A Elsner Sophia Mundigl Giang Vu Vi Tran Stephen W Barthold Nicole Baumgarth Source Type: research
Borrelia burgdorferi Infection-Induced Persistent IgM Secretion Controls Bacteremia, but Not Bacterial Dissemination or Tissue Burden
J Immunol. 2023 Oct 2:ji2300384. doi: 10.4049/jimmunol.2300384. Online ahead of print.ABSTRACTInfection with Borrelia burgdorferi causes Lyme disease in humans. In small rodents, the natural reservoir species of this spirochete, infections lead to only modest disease manifestations, despite causing persistence infection. Although B cell responses are central for controlling bacterial tissue burden and disease manifestations, they lack classical aspects of T-dependent responses, such as sustained IgG affinity maturation and longevity, corresponding with a rapid collapse of germinal centers. Instead, the Ab response is chara...
Source: Journal of Immunology - October 2, 2023 Category: Allergy & Immunology Authors: Christine J Hastey Kimberly J Olsen Rebecca A Elsner Sophia Mundigl Giang Vu Vi Tran Stephen W Barthold Nicole Baumgarth Source Type: research
Borrelia persica infection in wild carnivores in Israel: molecular characterization and new potential reservoirs
Borrelia persica causes tick-borne relapsing fever in Israel, the eastern Mediterranean basin, and Asia. Relapsing fever is associated with severe illness and potentially death in humans and animals. Since B. per... (Source: Parasites and Vectors)
Source: Parasites and Vectors - September 26, 2023 Category: Microbiology Authors: Dor Shwartz, Yaarit Nachum-Biala, Stephanie Oren, Kobi Aharoni, Nir Edery, Lior Moss, Roni King, Roi Lapid, Reinhard K. Straubinger and Gad Baneth Tags: Research Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | PMC:PMC10521598 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | PMC:PMC10521598 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | PMC:PMC10521598 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
Emerg Infect Dis. 2023 Oct;29(10):2173-2175. doi: 10.3201/eid2910.230907.ABSTRACTWe detected Borrelia bavariensis in Ixodes ricinus ticks collected near 2 towns in the United Kingdom. Human B. bavariensis infections have not been reported previously in the country, underscoring the value of tick surveillance to warn of emerging human disease. B. bavariensis should be considered in patients with suspected neuroborreliosis.PMID:37735806 | PMC:PMC10521598 | DOI:10.3201/eid2910.230907 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Grace Plahe Jessica L Hall David Johnson Lucy Gilbert Richard J Birtles Source Type: research
Molecular Detection of Borrelia spp. in Ticks of Sheep and Goats by Nested PCR Method in West Azerbaijan Province, Iran
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - September 19, 2023 Category: Infectious Diseases Authors: Ahmad Enferadi Abdolghaffar Ownagh Mousa Tavassoli Source Type: research
Borrelia bavariensis in Questing Ixodes ricinus Ticks, United Kingdom
G. Plahe et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - September 18, 2023 Category: Infectious Diseases Source Type: research
Genome diversity of Borrelia garinii sustained in marine transmission cycles by Ixodes uriae does not match host association but reflects the strains evolutionary history
Infect Genet Evol. 2023 Sep 14:105502. doi: 10.1016/j.meegid.2023.105502. Online ahead of print.ABSTRACTBorrelia burgdorferi sensu lato is a species complex of spirochetal bacteria that occupy different ecological niches which is reflected in their reservoir host- and vector-associations. Borrelia genomes possess numerous linear and circular plasmids. Proteins encoded by plasmid genes play a major role in host- and vector-interaction and are important for Borrelia niche adaptation. However, the plasmid composition and therewith the gene repertoire may vary even in strains of a single species. Borrelia garinii, one of the s...
Source: Infection, Genetics and Evolution - September 16, 2023 Category: Genetics & Stem Cells Authors: Gabriele Margos Markus Hofmann Sherwood Casjens Marlene Dupraz Susanne Heinzinger Christine Hartberger Sabrina Hepner Mercy Schmeusser Andreas Sing Volker Fingerle Karen D McCoy Source Type: research
Genome diversity of Borrelia garinii sustained in marine transmission cycles by Ixodes uriae does not match host association but reflects the strains evolutionary history
Infect Genet Evol. 2023 Sep 14:105502. doi: 10.1016/j.meegid.2023.105502. Online ahead of print.ABSTRACTBorrelia burgdorferi sensu lato is a species complex of spirochetal bacteria that occupy different ecological niches which is reflected in their reservoir host- and vector-associations. Borrelia genomes possess numerous linear and circular plasmids. Proteins encoded by plasmid genes play a major role in host- and vector-interaction and are important for Borrelia niche adaptation. However, the plasmid composition and therewith the gene repertoire may vary even in strains of a single species. Borrelia garinii, one of the s...
Source: Infection, Genetics and Evolution - September 16, 2023 Category: Genetics & Stem Cells Authors: Gabriele Margos Markus Hofmann Sherwood Casjens Marlene Dupraz Susanne Heinzinger Christine Hartberger Sabrina Hepner Mercy Schmeusser Andreas Sing Volker Fingerle Karen D McCoy Source Type: research
