A Case of Tick-borne Disease with Yezo Virus and Borrelia miyamotoi Coinfection
Intern Med. 2024 Mar 11. doi: 10.2169/internalmedicine.3225-23. Online ahead of print.ABSTRACTYezo virus is a novel virus transmitted by tick bites that causes fever with thrombocytopenia. To date, two reports have been published on patients with Yezo virus infection. However, the clinical characteristics of Yezo virus infection remain unclear. A patient who presented with fever, fatigue, headaches, and muscle pain and was admitted to our hospital. The patient had thrombocytopenia, leukopenia, and elevated liver enzyme and serum ferritin levels. The patient was diagnosed with Yezo virus and Borrelia miyamotoi coinfection b...
Source: Internal Medicine - March 10, 2024 Category: Internal Medicine Authors: Keiko Suzuki Satoshi Suzuki Hiroki Yamaguchi Yasutaka Kakinoki Source Type: research
New records of pathogenic bacteria in different species of fleas collected from domestic and peridomestic animals in Spain. A potential zoonotic threat?
Comp Immunol Microbiol Infect Dis. 2024 Mar 4;107:102153. doi: 10.1016/j.cimid.2024.102153. Online ahead of print.ABSTRACTClimate change is causing many vectors of infectious diseases to expand their geographic distribution as well as the pathogens they transmit are also conditioned by temperature for their multiplication. Within this context, it is worth highlighting the significant role that fleas can play as vectors of important pathogenic bacteria. For this purpose, our efforts focused on detecting and identifying a total of 9 bacterial genera (Rickettsia sp.; Bartonella sp.; Yersinia sp.; Wolbachia sp., Mycobacterium ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2024 Category: Allergy & Immunology Authors: Antonio Zurita Ignacio Trujillo Cristina Cutillas Source Type: research
New records of pathogenic bacteria in different species of fleas collected from domestic and peridomestic animals in Spain. A potential zoonotic threat?
Comp Immunol Microbiol Infect Dis. 2024 Mar 4;107:102153. doi: 10.1016/j.cimid.2024.102153. Online ahead of print.ABSTRACTClimate change is causing many vectors of infectious diseases to expand their geographic distribution as well as the pathogens they transmit are also conditioned by temperature for their multiplication. Within this context, it is worth highlighting the significant role that fleas can play as vectors of important pathogenic bacteria. For this purpose, our efforts focused on detecting and identifying a total of 9 bacterial genera (Rickettsia sp.; Bartonella sp.; Yersinia sp.; Wolbachia sp., Mycobacterium ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2024 Category: Allergy & Immunology Authors: Antonio Zurita Ignacio Trujillo Cristina Cutillas Source Type: research
New records of pathogenic bacteria in different species of fleas collected from domestic and peridomestic animals in Spain. A potential zoonotic threat?
Comp Immunol Microbiol Infect Dis. 2024 Mar 4;107:102153. doi: 10.1016/j.cimid.2024.102153. Online ahead of print.ABSTRACTClimate change is causing many vectors of infectious diseases to expand their geographic distribution as well as the pathogens they transmit are also conditioned by temperature for their multiplication. Within this context, it is worth highlighting the significant role that fleas can play as vectors of important pathogenic bacteria. For this purpose, our efforts focused on detecting and identifying a total of 9 bacterial genera (Rickettsia sp.; Bartonella sp.; Yersinia sp.; Wolbachia sp., Mycobacterium ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2024 Category: Allergy & Immunology Authors: Antonio Zurita Ignacio Trujillo Cristina Cutillas Source Type: research
New records of pathogenic bacteria in different species of fleas collected from domestic and peridomestic animals in Spain. A potential zoonotic threat?
Comp Immunol Microbiol Infect Dis. 2024 Mar 4;107:102153. doi: 10.1016/j.cimid.2024.102153. Online ahead of print.ABSTRACTClimate change is causing many vectors of infectious diseases to expand their geographic distribution as well as the pathogens they transmit are also conditioned by temperature for their multiplication. Within this context, it is worth highlighting the significant role that fleas can play as vectors of important pathogenic bacteria. For this purpose, our efforts focused on detecting and identifying a total of 9 bacterial genera (Rickettsia sp.; Bartonella sp.; Yersinia sp.; Wolbachia sp., Mycobacterium ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2024 Category: Allergy & Immunology Authors: Antonio Zurita Ignacio Trujillo Cristina Cutillas Source Type: research
New records of pathogenic bacteria in different species of fleas collected from domestic and peridomestic animals in Spain. A potential zoonotic threat?
Comp Immunol Microbiol Infect Dis. 2024 Mar 4;107:102153. doi: 10.1016/j.cimid.2024.102153. Online ahead of print.ABSTRACTClimate change is causing many vectors of infectious diseases to expand their geographic distribution as well as the pathogens they transmit are also conditioned by temperature for their multiplication. Within this context, it is worth highlighting the significant role that fleas can play as vectors of important pathogenic bacteria. For this purpose, our efforts focused on detecting and identifying a total of 9 bacterial genera (Rickettsia sp.; Bartonella sp.; Yersinia sp.; Wolbachia sp., Mycobacterium ...
Source: Comparative immunology, microbiology and infectious diseases. - March 9, 2024 Category: Allergy & Immunology Authors: Antonio Zurita Ignacio Trujillo Cristina Cutillas Source Type: research
Screening Marine Microbial Metabolites as Promising Inhibitors of < em > Borrelia garinii < /em > : A Structural Docking Approach towards Developing Novel Lyme Disease Treatment
In this study, we employed structural docking-based screening to identify potential lead-like inhibitors against the bacterium. We first identified the core essential genome fraction of the bacterium, using 37 strains. Later, we screened a library of lead-like marine microbial metabolites (n = 4730) against the arginine deiminase (ADI) protein of Borrelia garinii. This protein plays a crucial role in the survival of the bacteria, and inhibiting it can kill the bacterium. The prioritized lead compounds demonstrating favorable binding energies and interactions with the active site of ADI were then evaluated for their drug-li...
Source: Biomed Res - March 8, 2024 Category: Research Authors: Zarrin Basharat Sadia Sattar Ammar Abdulraheem Bahauddin Abdulaziz K Al Mouslem Ghallab Alotaibi Source Type: research
Screening Marine Microbial Metabolites as Promising Inhibitors of < em > Borrelia garinii < /em > : A Structural Docking Approach towards Developing Novel Lyme Disease Treatment
In this study, we employed structural docking-based screening to identify potential lead-like inhibitors against the bacterium. We first identified the core essential genome fraction of the bacterium, using 37 strains. Later, we screened a library of lead-like marine microbial metabolites (n = 4730) against the arginine deiminase (ADI) protein of Borrelia garinii. This protein plays a crucial role in the survival of the bacteria, and inhibiting it can kill the bacterium. The prioritized lead compounds demonstrating favorable binding energies and interactions with the active site of ADI were then evaluated for their drug-li...
Source: Biomed Res - March 8, 2024 Category: Research Authors: Zarrin Basharat Sadia Sattar Ammar Abdulraheem Bahauddin Abdulaziz K Al Mouslem Ghallab Alotaibi Source Type: research
Surveillance for < em > Ixodes scapularis < /em > and < em > Ixodes pacificus < /em > ticks and their associated pathogens in Canada, 2020
CONCLUSION: This article provides a snapshot of the distribution of I. scapularis and I. pacificus and their associated human pathogens in Canada in 2020, which can help assess the risk of exposure to tick-borne pathogens in different provinces.PMID:38444700 | PMC:PMC10914093 | DOI:10.14745/ccdr.v49i06a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Christy Wilson Salima Gasmi Annie-Claude Bourgeois Jacqueline Badcock Justin Carr Navdeep Chahil Heather Coatsworth Antonia Dibernardo Priya Goundar Patrick Leighton Min-Kuang Lee Muhammad Morshed Marion Ripoche Jade Savage eTick, Hanan Smadi3, Christa Sm Source Type: research
Surveillance for < em > Ixodes scapularis < /em > and < em > Ixodes pacificus < /em > ticks and their associated pathogens in Canada, 2020
CONCLUSION: This article provides a snapshot of the distribution of I. scapularis and I. pacificus and their associated human pathogens in Canada in 2020, which can help assess the risk of exposure to tick-borne pathogens in different provinces.PMID:38444700 | PMC:PMC10914093 | DOI:10.14745/ccdr.v49i06a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Christy Wilson Salima Gasmi Annie-Claude Bourgeois Jacqueline Badcock Justin Carr Navdeep Chahil Heather Coatsworth Antonia Dibernardo Priya Goundar Patrick Leighton Min-Kuang Lee Muhammad Morshed Marion Ripoche Jade Savage eTick, Hanan Smadi3, Christa Sm Source Type: research
