A case report of ventricular fibrillation following Shockwave intravascular lithotripsy during percutaneous coronary intervention
Shockwave intravascular lithotripsy (S-IVL) is widely used during percutaneous coronary intervention (PCI) of calcified coronary arteries. Ventricular capture beats during S-IVL are common but arrhythmias are ... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 23, 2024 Category: Cardiology Authors: Lars Jakobsen, Evald H øj Christiansen and Troels Thim Tags: Case Report Source Type: research

Burden of cardiac arrhythmias in patients with acute myocardial infarction and their impact on hospitalization outcomes: insights from China acute myocardial infarction (CAMI) registry
The coexistence of cardiac arrhythmias in patients with acute myocardial infarction (AMI) usually exhibits poor prognosis. However, there are few contemporary data available on the burden of cardiac arrhythmia... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 23, 2024 Category: Cardiology Authors: Xu Xu, Zhao Wang, Jingang Yang, Xiaohan Fan and Yuejin Yang Tags: Research Source Type: research

Patient vulnerability in stereotactic arrhythmia radioablation  (STAR): a preliminary ethical appraisal from the STOPSTORM.eu consortium
AbstractThis preliminary ethical appraisal from the STOPSTORM.eu consortium is meant to raise critical points that clinicians administering stereotactic arrhythmia radioablation should consider to meet the highest standards in medical ethics and thus promote quality of life of patients recruited for radiotherapy treatments at a  stage in which they experience a significant degree of vulnerability. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 23, 2024 Category: Cancer & Oncology Source Type: research

Classification Method of ECG Signals Based on RANet
AbstractBackgroundElectrocardiograms (ECG) are an important source of information on human heart health and are widely used to detect different types of arrhythmias.ObjectiveWith the advancement of deep learning, end-to-end ECG classification models based on neural networks have been developed. However, deeper network layers lead to gradient vanishing. Moreover, different channels and periods of an ECG signal hold varying significance for identifying different types of ECG abnormalities.MethodsTo solve these two problems, an ECG classification method based on a residual attention neural network is proposed i...
Source: Cardiovascular Engineering and Technology - April 23, 2024 Category: Cardiology Source Type: research

Atrial fibrillation de novo in acute coronary syndrome
Arch Cardiol Mex. 2024;94(2):181-190. doi: 10.24875/ACM.23000008.ABSTRACTOne of the complications during an acute coronary syndrome event is the presence of arrhythmias. Among them, those of the supraventricular type, especially atrial fibrillation, carry a poor prognosis both in the short and long term, being the cause of situations such as cerebrovascular event, ventricular arrhythmias, and increased mortality. The arrhythmia tends to appear in a certain population group with particular risk factors during the index event in approximately 10% of cases. Appropriate treatment at the time of its onset, thanks to the use of ...
Source: Archivos de Cardiologia de Mexico - April 22, 2024 Category: Cardiology Authors: David Trujillo-Flores Jos é de J García-Mendoza Source Type: research

Grouped mixtures of air pollutants and seasonal temperature anomalies and cardiovascular hospitalizations among U.S. Residents
CONCLUSIONS: Our findings identified critical pollutants for targeted emission controls and suggested that abnormal temperature changes chronically affected cardiovascular health by interacting with air pollution, not directly.PMID:38648692 | DOI:10.1016/j.envint.2024.108651 (Source: Environment International)
Source: Environment International - April 22, 2024 Category: Environmental Health Authors: Yaguang Wei Heresh Amini Xinye Qiu Edgar Castro Tingfan Jin Kanhua Yin Bryan N Vu James Healy Yijing Feng Jiangshan Zhang Brent Coull Joel Schwartz Source Type: research

Cardiovascular and Respiratory Effects of Cannabis Use by Route of Administration: A Systematic Review
Conclusion: Cannabis use does cause cardiovascular and respiratory effects, but the conclusion remains tentative of the cardiovascular and respiratory effects by route of administration due to methodological limitations of the studies.PMID:38644600 | DOI:10.1080/10826084.2024.2341317 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 22, 2024 Category: Addiction Authors: Sadandaula Rose Muheriwa-Matemba Amrit Baral Alireza Abdshah Bria-Necole Amazing Diggs Kathryn Sierra Gerber Collazos Kyana Breche Morris Sarah Elizabeth Messiah Denise Christina Vidot Source Type: research

Atrial fibrillation de novo in acute coronary syndrome
Arch Cardiol Mex. 2024;94(2):181-190. doi: 10.24875/ACM.23000008.ABSTRACTOne of the complications during an acute coronary syndrome event is the presence of arrhythmias. Among them, those of the supraventricular type, especially atrial fibrillation, carry a poor prognosis both in the short and long term, being the cause of situations such as cerebrovascular event, ventricular arrhythmias, and increased mortality. The arrhythmia tends to appear in a certain population group with particular risk factors during the index event in approximately 10% of cases. Appropriate treatment at the time of its onset, thanks to the use of ...
Source: Archivos de Cardiologia de Mexico - April 22, 2024 Category: Cardiology Authors: David Trujillo-Flores Jos é de J García-Mendoza Source Type: research

Cardiovascular and Respiratory Effects of Cannabis Use by Route of Administration: A Systematic Review
Conclusion: Cannabis use does cause cardiovascular and respiratory effects, but the conclusion remains tentative of the cardiovascular and respiratory effects by route of administration due to methodological limitations of the studies.PMID:38644600 | DOI:10.1080/10826084.2024.2341317 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 22, 2024 Category: Addiction Authors: Sadandaula Rose Muheriwa-Matemba Amrit Baral Alireza Abdshah Bria-Necole Amazing Diggs Kathryn Sierra Gerber Collazos Kyana Breche Morris Sarah Elizabeth Messiah Denise Christina Vidot Source Type: research

Editorial to “Association of Left Atrial Appendage Morphology and Function with Stroke and Transient Ischemic Attack in Atrial Fibrillation Patients”
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice and is an independent risk factor for strokes. A thromboembolic event risk assessment based on the CHA2DS2-VASc score is recommended by the guidelines. However, strokes also occur even in some populations with low CHA2DS2-VASc scores. Thus, new factors to improve the risk stratification of thromboembolic events are needed. A major embolic source associated with AF is the left atrial appendage (LAA). Previous reports showed that the LAA endocardium has more enhanced expression of a prothrombotic profile and proinflammatory proteins tha...
Source: The American Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Satoshi Higa Tags: Editorial Source Type: research

Targeting NLRP3 signaling reduces myocarditis-induced arrhythmogenesis and cardiac remodeling
Myocarditis substantially increases the risk of ventricular arrhythmia. Approximately 30% of all ventricular arrhythmia cases in patients with myocarditis originate from the right ventricular outflow tract (RV... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - April 22, 2024 Category: Biomedical Science Authors: Chye-Gen Chin, Yao-Chang Chen, Fong-Jhih Lin, Yung-Kuo Lin, Yen-Yu Lu, Tzu-Yu Cheng, Shih-Ann Chen and Yi-Jen Chen Tags: Research Source Type: research

Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor
Chem Pharm Bull (Tokyo). 2024;72(4):399-407. doi: 10.1248/cpb.c24-00114.ABSTRACTRyanodine receptor 2 (RyR2) is a large Ca2+-release channel in the sarcoplasmic reticulum (SR) of cardiac muscle cells. It serves to release Ca2+ from the SR into the cytosol to initiate muscle contraction. RyR2 overactivation is associated with arrhythmogenic cardiac disease, but few specific inhibitors have been reported so far. Here, we identified an RyR2-selective inhibitor 1 from the chemical compound library and synthesized it from glycolic acid. Synthesis of various derivatives to investigate the structure-activity relationship of each s...
Source: Chemical and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Ryosuke Ishida Xi Zeng Nagomi Kurebayashi Takashi Murayama Shuichi Mori Hiroyuki Kagechika Source Type: research

Discovery and Structure-Activity Relationship of a Ryanodine Receptor 2 Inhibitor
Chem Pharm Bull (Tokyo). 2024;72(4):399-407. doi: 10.1248/cpb.c24-00114.ABSTRACTRyanodine receptor 2 (RyR2) is a large Ca2+-release channel in the sarcoplasmic reticulum (SR) of cardiac muscle cells. It serves to release Ca2+ from the SR into the cytosol to initiate muscle contraction. RyR2 overactivation is associated with arrhythmogenic cardiac disease, but few specific inhibitors have been reported so far. Here, we identified an RyR2-selective inhibitor 1 from the chemical compound library and synthesized it from glycolic acid. Synthesis of various derivatives to investigate the structure-activity relationship of each s...
Source: Chemical and Pharmaceutical Bulletin - April 21, 2024 Category: Drugs & Pharmacology Authors: Ryosuke Ishida Xi Zeng Nagomi Kurebayashi Takashi Murayama Shuichi Mori Hiroyuki Kagechika Source Type: research

Analyses of lncRNA and mRNA profiles in recurrent atrial fibrillation after catheter ablation
ConclusionsThe recurrence of atrial fibrillation after catheter ablation may be associated with immune responses and fibrosis, with the extracellular matrix playing a crucial role. TMEM51-AS1-201 has been identified as a potential key target for AF recurrence after catheter ablation. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 20, 2024 Category: Research Source Type: research

Elucidating effects of the environmental pollutant benzo[a]pyrene [BaP] on cardiac arrhythmogenicity
Environmental pollution causes cardiovascular disease, heart failure, and arrythmias [1 –4]. Wildfire emissions are a complex mixture composed of particulate matter (PM), carbon monoxide, methane, nitrous oxide, and polyaromatic hydrocarbons, among others [5], which are linked to arrhythmias [6]. Benzo[a]pyrene is a polyaromatic hydrocarbon and known carcinogen in animal models and i s implicated in breast cancer, lung cancer, liver cancer, and skin cancer [7]. Therefore, the further impact of BaP on the cardiovascular system merits further investigation. (Source: Journal of Molecular and Cellular Cardiology)
Source: Journal of Molecular and Cellular Cardiology - April 20, 2024 Category: Cytology Authors: Johnson Y. Yang, Gema Mond éjar-Parreño, James W.S. Jahng, Yu Lu, Naomi Hamburg, Kari C. Nadeau, Daniel J. Conklin, Ronglih Liao, Mark Chandy, Joseph C. Wu Tags: Letter to the editor Source Type: research