Differential expression of microRNA, miR-150 and enhancer of zeste homolog 2 (EZH2) in peripheral blood cells as early prognostic markers of severe forms of dengue
Dengue presents a wide clinical spectrum. Most patients recover following a self-limiting non-severe clinical course. A small proportion of patients progress to severe disease, mostly characterized by plasma l... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 18, 2020 Category: Biomedical Science Authors: Harsha Hapugaswatta, Pubudu Amarasena, Ranjan Premaratna, Kapila N. Seneviratne and Nimanthi Jayathilaka Tags: Research Source Type: research

Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing serious nosocomial infections, which is considered as the most threatening Gram-negative bacteria (GNB). Outer membrane protei... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 18, 2020 Category: Biomedical Science Authors: Dan Nie, Yue Hu, Zhou Chen, Mingkai Li, Zheng Hou, Xiaoxing Luo, Xinggang Mao and Xiaoyan Xue Tags: Review Source Type: research

Photoacoustic imaging of cells in a three-dimensional microenvironment
Imaging live cells in a three-dimensional (3D) culture system yields more accurate information and spatial visualization of the interplay of cells and the surrounding matrix components compared to using a two-... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 17, 2020 Category: Biomedical Science Authors: Wei-Wen Liu and Pai-Chi Li Tags: Review Source Type: research

Amelioration of bleomycin-induced pulmonary fibrosis via TGF- β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells
Galectin-9 is a β-galactoside-binding protein with two carbohydrate recognition domains. Recent studies have revealed that galectin-9 regulates cellular biological reactions and plays a pivotal role in fibrosi... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 15, 2020 Category: Biomedical Science Authors: Yu-An Hsu, Ching-Yao Chang, Joung-Liang Lan, Ju-Pi Li, Hui-Ju Lin, Chih-Sheng Chen, Lei Wan and Fu-Tong Liu Tags: Research Source Type: research

Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells
Recent advancements in cancer biology field suggest that glucose metabolism is a potential target for cancer treatment. However, little if anything is known about the metabolic profile of cancer stem cells (CS... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 13, 2020 Category: Biomedical Science Authors: Han-Shui Hsu, Chen-Chi Liu, Jiun-Han Lin, Tien-Wei Hsu, Jyuan-Wei Hsu, Anna Fen-Yau Li and Shih-Chieh Hung Tags: Research Source Type: research

Cellular receptors for enterovirus A71
Enterovirus 71 (EV-A71) is one of the major causative agents of hand, foot, and mouth disease. EV-A71 infection is sometimes associated with severe neurological diseases such as acute encephalitis, acute flacc... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 10, 2020 Category: Biomedical Science Authors: Kyousuke Kobayashi and Satoshi Koike Tags: Review Source Type: research

Neuropeptide S-initiated sequential cascade mediated by OX1, NK1, mGlu5 and CB1 receptors: a pivotal role in stress-induced analgesia
Stress-induced analgesia (SIA) is an evolutionarily conserved phenomenon during stress. Neuropeptide S (NPS), orexins, substance P, glutamate and endocannabinoids are known to be involved in stress and/or SIA,... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 9, 2020 Category: Biomedical Science Authors: Ming Tatt Lee, Yu-Ting Chiu, Yu-Chun Chiu, Chia Chun Hor, Hsin-Jung Lee, Remo Guerrini, Girolamo Calo and Lih-Chu Chiou Tags: Research Source Type: research

Translation control of Enterovirus A71 gene expression
Upon EV-A71 infection of a host cell, EV-A71 RNA is translated into a viral polyprotein. Although EV-A71 can use the cellular translation machinery to produce viral proteins, unlike cellular translation, which... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 8, 2020 Category: Biomedical Science Authors: Ming-Chih Lai, Han-Hsiang Chen, Peng Xu and Robert Y. L. Wang Tags: Review Source Type: research

Structural basis of polyethylene glycol recognition by antibody
Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for speci... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 7, 2020 Category: Biomedical Science Authors: Cheng-Chung Lee, Yu-Cheng Su, Tzu-Ping Ko, Li-Ling Lin, Chih-Ya Yang, Stanley Shi-Chung Chang, Steve R. Roffler and Andrew H.-J. Wang Tags: Research Source Type: research

Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation
Influenza A viruses cause epidemics/severe pandemics that pose a great global health threat. Among eight viral RNA segments, the multiple functions of nucleoprotein (NP) play important roles in viral replicati... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 6, 2020 Category: Biomedical Science Authors: Su-Jhen Hung, Yin-Mei Hsu, Sheng-Wen Huang, Huey-Pin Tsai, Leo Yi Yang Lee, Aeron C. Hurt, Ian G. Barr, Shin-Ru Shih and Jen-Ren Wang Tags: Research Source Type: research

Clinical trials of new drugs for Alzheimer disease
Alzheimer disease (AD) accounts for 60 –70% of dementia cases. Given the seriousness of the disease and continual increase in patient numbers, developing effective therapies to treat AD has become urgent. Prese... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 6, 2020 Category: Biomedical Science Authors: Li-Kai Huang, Shu-Ping Chao and Chaur-Jong Hu Tags: Review Source Type: research

Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model
The FDA approved drug granulocyte-colony stimulating factor (G-CSF) displays anti-apoptotic and immunomodulatory properties with neurogenesis and angiogenic functions. It is known to demonstrate neuroprotectiv... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 6, 2020 Category: Biomedical Science Authors: Jigar Modi, Janet Menzie-Suderam, Hongyuan Xu, Paola Trujillo, Kristen Medley, Michael L. Marshall, Rui Tao, Howard Prentice and Jang-Yen Wu Tags: Research Source Type: research

7-oxo-DHEA enhances impaired M. tuberculosis-specific T cell responses during HIV-TB coinfection
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), affecting approximately one third of the world ’s population. Development of an adequate immune response will determine disease progres... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 6, 2020 Category: Biomedical Science Authors: Mar ía Belén Vecchione, Natalia Laufer, Omar Sued, Marcelo Corti, Horacio Salomon and Maria Florencia Quiroga Tags: Research Source Type: research

Melatonin restores Muc2 depletion induced by V. vulnificus VvpM via melatonin receptor 2 coupling with G αq
Melatonin (5-methoxy-N-acetyltryptamine), a hormone produced in the pineal gland, has a variety of biological functions as an antioxidant, but a functional role of melatonin in the regulation of intestinal muc... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 6, 2020 Category: Biomedical Science Authors: Young-Min Lee, Jong Pil Park, Young Hyun Jung, Hyun Jik Lee, Jun Sung Kim, Gee Euhn Choi, Ho Jae Han and Sei-Jung Lee Tags: Research Source Type: research

Dopamine D3 receptor and GSK3 β signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice
Over-stimulation of dopamine signaling is thought to underlie the pathophysiology of a list of mental disorders, such as psychosis, mania and attention-deficit/hyperactivity disorder. These disorders are frequ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Pi-Kai Chang, Jung Chu, Ya-Ting Tsai, Yan-Heng Lai and Jin-Chung Chen Tags: Research Source Type: research

Therapeutic applications of nucleic acid aptamers in microbial infections
Today, the treatment of bacterial infections is a major challenge, due to growing rate of multidrug-resistant bacteria, complication of treatment and increased healthcare costs. Moreover, new treatments for ba... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Shima Afrasiabi, Maryam Pourhajibagher, Reza Raoofian, Maryam Tabarzad and Abbas Bahador Tags: Review Source Type: research

Co-introduction of plasmids harbouring the carbapenemase genes, blaNDM-1 and blaOXA-232, increases fitness and virulence of bacterial host
Bacterial isolates with multiple plasmids harbouring different carbapenemase genes have emerged and been identified repeatedly, despite a general notion that plasmids confer fitness cost in bacterial host. In ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Haejeong Lee, Juyoun Shin, Yeun-Jun Chung, Myungseo Park, Kyeong Jin Kang, Jin Yang Baek, Dongwoo Shin, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song and Kwan Soo Ko Tags: Research Source Type: research

Synthetic carbohydrate-based vaccines: challenges and opportunities
Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Ravinder Mettu, Chiang-Yun Chen and Chung-Yi Wu Tags: Review Source Type: research

Siglec-15: a potential regulator of osteoporosis, cancer, and infectious diseases
Siglec-15 is a member of the Siglec family of glycan-recognition proteins, primarily expressed on a subset of myeloid cells. Siglec-15 has been known to be involved in osteoclast differentiation, and is consid... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Takashi Angata Tags: Review Source Type: research

Detection and phylogeny of Staphylococcus aureus sequence type 398 in Taiwan
Methicillin-resistant Staphylococcus aureus (MRSA) ST398 is a livestock associated-bacterium that is most prevalent in Europe. Human-adapted MRSA ST398 was recently reported from China, but there is no data avail... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - January 3, 2020 Category: Biomedical Science Authors: Yhu-Chering Huang and Chih-Jung Chen Tags: Research Source Type: research

Correction to: Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway
In the original publication of this article [1] the name of the fifth author is uncorrect. The correct name of the fifth author should be Wei-Chiao Chang rather than Wei-Chao Chang. The original publication ha... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - December 23, 2019 Category: Biomedical Science Authors: Grace Wakabayashi, Yu-Ching Lee, Frank Luh, Chun-Nan Kuo, Wei-Chiao Chang and Yun Yen Tags: Correction Source Type: research

Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients
This study aimed to investigate whether Dectin-2 blockade by antagonistic monoclonal antibodie... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - December 20, 2019 Category: Biomedical Science Authors: Ming-Han Chen, Ming-Ting Huang, Wen-Kuang Yu, Shinn-Shing Lee, Jia-Horng Wang, Ting-Jen R. Cheng, Michael R. Bowman and Shie-Liang Hsieh Tags: Research Source Type: research

Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway
Dramatic advances in immune therapy have emerged as a promising strategy in cancer therapeutics. In addition to chemotherapy and radiotherapy, inhibitors targeting immune-checkpoint molecules such as cytotoxic... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - December 5, 2019 Category: Biomedical Science Authors: Grace Wakabayashi, Yu-Ching Lee, Frank Luh, Chun-Nan Kuo, Wei-Chao Chang and Yun Yen Tags: Review Source Type: research

The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury
Insulin-like growth factor 1 (IGF-1) is an important pleiotropic hormone that exerts neuroprotective and neuroreparative effects after a brain injury. However, the roles of IGF-1 variants in mild traumatic brain ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - December 2, 2019 Category: Biomedical Science Authors: Yu-Jia Wang, Henry Sung-Ching Wong, Chung-Che Wu, Yung-Hsiao Chiang, Wen-Ta Chiu, Kai-Yun Chen and Wei-Chiao Chang Tags: Research Source Type: research

Interplays between Enterovirus A71 and the innate immune system
Enterovirus A71 (EV-A71) is a growing threat to public health, particularly in the Asia-Pacific region. EV-A71 infection is most prevalent in infants and children and causes a wide spectrum of clinical complic... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - December 2, 2019 Category: Biomedical Science Authors: Kuan-Ru Chen and Pin Ling Tags: Review Source Type: research

Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model
Enterovirus 71 (EV71 or EV-A71) was first identified in California about half a century ago. In recent years, outbreaks of EV-A71 were prevalent worldwide, including Taiwan, Malaysia, Singapore, Japan, and Chi... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - November 11, 2019 Category: Biomedical Science Authors: An-Ting Liou, Chun-Che Liao, Shu-Fan Chou, Ya-Shu Chang, Chih-Shin Chang and Chiaho Shih Tags: Research Source Type: research

Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women
Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria. Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms a... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - November 8, 2019 Category: Biomedical Science Authors: Mahdiyeh Harati-Sadegh, Leila Kohan, Batool Teimoori, Mehrnaz Mehrabani and Saeedeh Salimi Tags: Research Source Type: research

Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning
Genetic factors, dysregulation in the endocrine system, cytokine and paracrine factors are implicated in the pathogenesis of familial short stature (FSS). Nowadays, the treatment choice for FSS is limited, wit... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - November 7, 2019 Category: Biomedical Science Authors: Henry Sung-Ching Wong, Ying-Ju Lin, Hsing-Fang Lu, Wen-Ling Liao, Chien-Hsiun Chen, Jer-Yuarn Wu, Wei-Chiao Chang and Fuu-Jen Tsai Tags: Research Source Type: research

Beyond defense: regulation of neuronal morphogenesis and brain functions via Toll-like receptors
Toll-like receptors (TLRs) are well known as critical pattern recognition receptors that trigger innate immune responses. In addition, TLRs are expressed in neurons and may act as the gears in the neuronal det... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - November 4, 2019 Category: Biomedical Science Authors: Chiung-Ya Chen, Yi-Chun Shih, Yun-Fen Hung and Yi-Ping Hsueh Tags: Review Source Type: research

The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates
Effective neurorestorative therapies of neurodegenerative diseases must be developed. There is increasing interest in using human platelet lysates, rich in neurotrophic factors, as novel disease-modifying stra... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 31, 2019 Category: Biomedical Science Authors: Ouada Nebie, David Devos, Val érie Vingtdeux, Lassina Barro, Jean-Christophe Devedjian, Aurélie Jonneaux, Ming-Li Chou, Régis Bordet, Luc Buée, Folke Knutson, David Blum and Thierry Burnouf Tags: Research Source Type: research

Human iPSC banking: barriers and opportunities
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based d... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 28, 2019 Category: Biomedical Science Authors: Ching-Ying Huang, Chun-Lin Liu, Chien-Yu Ting, Yueh-Ting Chiu, Yu-Che Cheng, Martin W. Nicholson and Patrick C. H. Hsieh Tags: Review Source Type: research

Liver microsystems in vitro for drug response
Engineering approaches were adopted for liver microsystems to recapitulate cell arrangements and culture microenvironments in vivo for sensitive, high-throughput and biomimetic drug screening. This review intr... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 28, 2019 Category: Biomedical Science Authors: Jyong-Huei Lee, Kuan-Lun Ho and Shih-Kang Fan Tags: Review Source Type: research

Active roles of dysfunctional vascular endothelium in fibrosis and cancer
Chronic inflammation is the underlying pathological condition that results in fibrotic diseases. More recently, many forms of cancer have also been linked to chronic tissue inflammation. While stromal immune c... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 28, 2019 Category: Biomedical Science Authors: Tien Hsu, Hieu-Huy Nguyen-Tran and Maria Trojanowska Tags: Review Source Type: research

DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS na ïve HIV-infected patients: a retrospective study
Most of the circulating Vitamin D (VitD) is transported bound to vitamin D-binding protein (DBP), and several DBP single nucleotide polymorphisms (SNPs) have been related to circulating VitD concentration and ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 23, 2019 Category: Biomedical Science Authors: Mar ía Ángeles JIMÉNEZ-SOUSA, José Luis JIMÉNEZ, Amanda FERNÁNDEZ-RODRÍGUEZ, José María BELLÓN, Carmen RODRÍGUEZ, Melchor RIERA, Joaquín PORTILLA, Ángeles CASTRO, María Ángeles MUÑOZ-FERNÁNDEZ and Salvador RESINO Tags: Research Source Type: research

Development of effective anti-influenza drugs: congeners and conjugates – a review
Influenza is a long-standing health problem. For treatment of seasonal flu and possible pandemic infections, there is a need to develop new anti-influenza drugs that have good bioavailability against a broad s... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 23, 2019 Category: Biomedical Science Authors: Jiun-Jie Shie and Jim-Min Fang Tags: Review Source Type: research

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers
Efficacy and safety are critical concerns when designing drug carriers. Nanoparticles are a particular type of carrier that has gained recent attention in cancer therapeutics. (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 23, 2019 Category: Biomedical Science Authors: Yi-Fan Chen, Yen-Hsin Wang, Cing-Syuan Lei, Chun A. Changou, Mark E. Davis and Yun Yen Tags: Review Source Type: research

MAP4K3/GLK in autoimmune disease, cancer and aging
MAP4K3 (also named GLK) is a serine/threonine kinase, which belongs to the mammalian Ste20-like kinase family. At 22  years of age, GLK was initially cloned and identified as an upstream activator of the MAPK J... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 22, 2019 Category: Biomedical Science Authors: Huai-Chia Chuang and Tse-Hua Tan Tags: Review Source Type: research

Ubiquitin-mediated regulation of autophagy
Autophagy is a major degradation pathway that utilizes lysosome hydrolases to degrade cellular constituents and is often induced under cellular stress conditions to restore cell homeostasis. Another prime degr... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 21, 2019 Category: Biomedical Science Authors: Ruey-Hwa Chen, Yu-Hsuan Chen and Tzu-Yu Huang Tags: Review Source Type: research

Enterovirus A71: virulence, antigenicity, and genetic evolution over the years
As a neurotropic virus, enterovirus A71 (EV-A71) emerge and remerge in the Asia-Pacific region since the 1990s, and has continuously been a threat to global public health, especially in children. Annually, EV-... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 21, 2019 Category: Biomedical Science Authors: Sheng-Wen Huang, Dayna Cheng and Jen-Ren Wang Tags: Review Source Type: research

Tumor-associated macrophages: an accomplice in solid tumor progression
In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly associated with poor survival in solid tumor... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 20, 2019 Category: Biomedical Science Authors: Yibing Chen, Yucen Song, Wei Du, Longlong Gong, Haocai Chang and Zhengzhi Zou Tags: Review Source Type: research

Yy1 regulates Senp1 contributing to AMPA receptor GluR1 expression following neuronal depolarization
Neuronal activity-induced changes in gene expression patterns are important mediators of neuronal plasticity. Many neuronal genes can be activated or inactivated in response to neuronal depolarization. Mechani... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 20, 2019 Category: Biomedical Science Authors: Tao Wu and Mary E. Donohoe Tags: Research Source Type: research

Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 19, 2019 Category: Biomedical Science Authors: Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen and Kwang-Yu Chang Tags: Research Source Type: research

M2e-based universal influenza vaccines: a historical overview and new approaches to development
The influenza A virus was isolated for the first time in 1931, and the first attempts to develop a vaccine against the virus began soon afterwards. In addition to causing seasonal epidemics, influenza viruses ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 19, 2019 Category: Biomedical Science Authors: Daria Mezhenskaya, Irina Isakova-Sivak and Larisa Rudenko Tags: Review Source Type: research

Smart polymers for cell therapy and precision medicine
Soft materials have been developed very rapidly in the biomedical field over the past 10  years because of advances in medical devices, cell therapy, and 3D printing for precision medicine. Smart polymers are o... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 18, 2019 Category: Biomedical Science Authors: Hung-Jin Huang, Yu-Liang Tsai, Shih-Ho Lin and Shan-hui Hsu Tags: Review Source Type: research

The analgesic effect of propofol associated with the inhibition of hypoxia inducible factor and inflammasome in complex regional pain syndrome
Complex regional pain syndrome (CRPS) is related to microcirculation impairment caused by tissue hypoxia and peripheral cytokine overproduction in the affected human limb and chronic post-ischemic pain (CPIP) ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 18, 2019 Category: Biomedical Science Authors: Hung-Tsung Hsiao, Yuan-Yuarn Liu, Jeffrey Chi-Fei Wang, Ya-Chi Lin and Yen-Chin Liu Tags: Research Source Type: research

The History of Enterovirus A71 Outbreaks and Molecular Epidemiology in the Asia-Pacific Region
Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a substantial pediatric hospitalization and burden... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 18, 2019 Category: Biomedical Science Authors: Jiratchaya Puenpa, Nasamon Wanlapakorn, Sompong Vongpunsawad and Yong Poovorawan Tags: Review Source Type: research

Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4
Transforming growth factor (TGF) family members play important roles in the regulation of corneal integrity, and the pathogenesis of corneal fibrosis. Currently, there are no effective agents targeting TGF- β s... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - October 9, 2019 Category: Biomedical Science Authors: Ying-Jen Chen, Shih-Ming Huang, Ming-Cheng Tai, Jiann-Torng Chen and Chang-Min Liang Tags: Research Source Type: research

Arginine vasopressin modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes
Atrial fibrillation (AF) frequently coexists with congestive heart failure (HF) and arginine vasopressin (AVP) V1 receptor antagonists are used to treat hyponatremia in HF. However, the role of AVP in HF-induc... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - September 17, 2019 Category: Biomedical Science Authors: Jen-Hung Huang, Yao-Chang Chen, Yen-Yu Lu, Yung-Kuo Lin, Shih-Ann Chen and Yi-Jen Chen Tags: Research Source Type: research

Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for the development of novel, s... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - September 10, 2019 Category: Biomedical Science Authors: Hadi Ghaffari, Ahmad Tavakoli, Abdolvahab Moradi, Alijan Tabarraei, Farah Bokharaei-Salim, Masoumeh Zahmatkeshan, Mohammad Farahmand, Davod Javanmard, Seyed Jalal Kiani, Maryam Esghaei, Vahid Pirhajati-Mahabadi, Angila Ataei-Pirkooh and Seyed Hamidreza Mo Tags: Research Source Type: research

Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria
This study sought to develop new strategies for reverting the resistance of pathogenic Gram-negative bacilli by a combination of conventional antibiotics, potent permeabilizers and natural beta lactamase inhib... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - September 9, 2019 Category: Biomedical Science Authors: Hala A. Farrag, Nagwa Abdallah, Mona M. K. Shehata and Ebthag M. Awad Tags: Research Source Type: research