Retraction Note to: Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis
(Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 30, 2022 Category: Biomedical Science Authors: Jingran Zhen, Jiangli Li, Xia Li, Xue Wang, Yaling Xiao, Zhengyi Sun and Qi Yu Tags: Retraction Note Source Type: research
Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far
Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of p... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 30, 2022 Category: Biomedical Science Authors: Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Zuzanna Drulis-Kawa, Kathryn Cater, Petar Knežević, Cyprian Winogradow, Karolina Amaro, Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Justyna Rękas and Andrzej Górski Tags: Review Source Type: research
Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Sp1 is involved in the recurrence of glioblastoma (GBM) due to the acquirement of resistance to temozolomide (TMZ). Particularly, the role of Sp1 in metabolic reprogramming for drug resistance remains unknown. (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 25, 2022 Category: Biomedical Science Authors: Yu-Ting Tsai, Wei-Lun Lo, Pin-Yuan Chen, Chiung-Yuan Ko, Jian-Ying Chuang, Tzu-Jen Kao, Wen-Bing Yang, Kwang-Yu Chang, Chia-Yang Hung, Ushio Kikkawa, Wen-Chang Chang and Tsung-I. Hsu Tags: Research Source Type: research
A chemical probe inhibitor targeting STAT1 restricts cancer stem cell traits and angiogenesis in colorectal cancer
Colorectal cancer (CRC) is a worldwide cancer with rising annual incidence. New medications for patients with CRC are still needed. Recently, fluorescent chemical probes have been developed for cancer imaging ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 22, 2022 Category: Biomedical Science Authors: Pei-Hsuan Chou, Cong-Kai Luo, Niaz Wali, Wen-Yen Lin, Shang-Kok Ng, Chun-Hao Wang, Mingtao Zhao, Sheng-Wei Lin, Pei-Ming Yang, Pin-Jung Liu, Jiun-Jie Shie and Tzu-Tang Wei Tags: Research Source Type: research
Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures
A short open reading frame (sORFs) constitutes ≤ 300 bases, encoding a microprotein or sORF-encoded protein (SEP) which comprises ≤ 100 amino acids. Traditionally dismissed by genome annotation pipelines as me... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 17, 2022 Category: Biomedical Science Authors: Alyssa Zi-Xin Leong, Pey Yee Lee, M. Aiman Mohtar, Saiful Effendi Syafruddin, Yuh-Fen Pung and Teck Yew Low Tags: Review Source Type: research
Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts
Androgenetic alopecia (AGA) is a genetic disorder caused by dihydrotestosterone (DHT), accompanied by the senescence of androgen-sensitive dermal papilla cells (DPCs) located in the base of hair follicles. DHT... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 7, 2022 Category: Biomedical Science Authors: Young Hyun Jung, Chang Woo Chae, Gee Euhn Choi, Him Cha Shin, Jae Ryong Lim, Han Seung Chang, Joonmo Park, Ji Hyeon Cho, Mo Ran Park, Hyun Jik Lee and Ho Jae Han Tags: Research Source Type: research
The role of the M-band myomesin proteins in muscle integrity and cardiac disease
Transversal structural elements in cross-striated muscles, such as the M-band or the Z-disc, anchor and mechanically stabilize the contractile apparatus and its minimal unit —the sarcomere. The ability of prote... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - March 7, 2022 Category: Biomedical Science Authors: Ekaterina P. Lamber, Pascale Guicheney and Nikos Pinotsis Tags: Review Source Type: research
Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference
Docetaxel has been approved by USFDA as a first-line treatment for castration-resistant prostate cancer (CRPC) patients. Patients receiving androgen deprivation therapy along with docetaxel result in superior ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 23, 2022 Category: Biomedical Science Authors: Yu-Ke Fu, Bi-Juan Wang, Jen-Chih Tseng, Shih-Han Huang, Ching-Yu Lin, Ying-Yu Kuo, Tzyh-Chyuan Hour and Chih-Pin Chuu Tags: Research Source Type: research
The pathogenic effects of particulate matter on neurodegeneration: a review
The increasing amount of particulate matter (PM) in the ambient air is a pressing public health issue globally. Epidemiological studies involving data from millions of patients or volunteers have associated PM... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 22, 2022 Category: Biomedical Science Authors: Ran You, Yuen-Shan Ho and Raymond Chuen-Chung Chang Tags: Review Source Type: research
Application of engineered extracellular vesicles for targeted tumor therapy
All cells, including prokaryotes and eukaryotes, could release extracellular vesicles (EVs). EVs contain many cellular components, including RNA, and surface proteins, and are essential for maintaining normal ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 21, 2022 Category: Biomedical Science Authors: Fusheng Zhang, Jinshuai Guo, Zhenghou Zhang, Meiqi Duan, Guang Wang, Yiping Qian, Haiying Zhao, Zhi Yang and Xiaofeng Jiang Tags: Review Source Type: research
The ambiguous role of obesity in oncology by promoting cancer but boosting antitumor immunotherapy
Obesity is nowadays considered a pandemic which prevalence ’s has been steadily increasingly in western countries. It is a dynamic, complex, and multifactorial disease which propitiates the development of sever... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 14, 2022 Category: Biomedical Science Authors: Jos é Antônio Fagundes Assumpção, Gabriel Pasquarelli-do-Nascimento, Mariana Saldanha Viegas Duarte, Martín Hernan Bonamino and Kelly Grace Magalhães Tags: Review Source Type: research
O-GlcNAc transferase couples MRE11 to transcriptionally active chromatin to suppress DNA damage
Transcription, metabolism and DNA damage response are tightly regulated to preserve the genomic integrity, and O-GlcNAc transferase (OGT) is positioned to connect the three. Prostate cancer is the most common can... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 14, 2022 Category: Biomedical Science Authors: Aishwarya Gondane, Samuel Girmay, Alma Helev ä, Satu Pallasaho, Massimo Loda and Harri M. Itkonen Tags: Research Source Type: research
Early innate immune response triggered by the human respiratory syncytial virus and its regulation by ubiquitination/deubiquitination processes
The human respiratory syncytial virus (HRSV) causes severe lower respiratory tract infections in infants and the elderly. An exuberant inadequate immune response is behind most of the pathology caused by the H... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 13, 2022 Category: Biomedical Science Authors: Mar ía Martín-Vicente, Salvador Resino and Isidoro Martínez Tags: Review Source Type: research
An auto-antibody identified from phenotypic directed screening platform shows host immunity against EV-A71 infection
Enterovirus A71 (EV-A71) is a neurotropic virus which may cause severe neural complications, especially in infants and children. The clinical manifestations include hand-foot-and-mouth disease, herpangina, bra... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 8, 2022 Category: Biomedical Science Authors: Yu-Wei Cheng, Yung-Chun Chuang, Sheng-Wen Huang, Ching-Chuan Liu and Jen-Ren Wang Tags: Research Source Type: research
Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use
K1 capsular polysaccharide (CPS)-associated Klebsiella pneumoniae is the primary cause of pyogenic liver abscesses (PLA) in Asia. Patients with PLA often have serious complications, ultimately leading to a mortal... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - February 7, 2022 Category: Biomedical Science Authors: I-Fan Tu, Tzu-Lung Lin, Feng-Ling Yang, I-Ming Lee, Wei-Lin Tu, Jiahn-Haur Liao, Tzu-Ping Ko, Wen-Jin Wu, Jia-Tsrong Jan, Meng-Ru Ho, Ching-Yi Chou, Andrew H.-J. Wang, Chung-Yi Wu, Jin-Town Wang, Kai-Fa Huang and Shih-Hsiung Wu Tags: Research Source Type: research
