Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy
Cancer immunotherapy has revolutionized treatment and led to an unprecedented wave of immuno-oncology research during the past two decades. In 2018, two pioneer immunotherapy innovators, Tasuku Honjo and James... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - June 22, 2021 Category: Biomedical Science Authors: Austin W. T. Chiang, Hratch M. Baghdassarian, Benjamin P. Kellman, Bokan Bao, James T. Sorrentino, Chenguang Liang, Chih-Chung Kuo, Helen O. Masson and Nathan E. Lewis Tags: Review Source Type: research
The promising shadow of microbubble over medical sciences: from fighting wide scope of prevalence disease to cancer eradication
Microbubbles are typically 0.5 –10 μm in size. Their size tends to make it easier for medication delivery mechanisms to navigate the body by allowing them to be swallowed more easily. The gas included in the mi... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - June 21, 2021 Category: Biomedical Science Authors: Ali Jangjou, Amir Hossein Meisami, Kazem Jamali, Mohammad Hadi Niakan, Milad Abbasi, Mostafa Shafiee, Majid Salehi, Ahmad Hosseinzadeh, Ali Mohammad Amani and Ahmad Vaez Tags: Review Source Type: research
Histone dynamics during DNA replication stress
Accurate and complete replication of the genome is essential not only for genome stability but also for cell viability. However, cells face constant threats to the replication process, such as spontaneous DNA ... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - June 19, 2021 Category: Biomedical Science Authors: Chia-Ling Hsu, Shin Yen Chong, Chia-Yeh Lin and Cheng-Fu Kao Tags: Review Source Type: research
Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma
Elevated transforming growth factor (TGF)- β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - June 17, 2021 Category: Biomedical Science Authors: Nozomi Igarashi, Megumi Honjo, Reiko Yamagishi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Toshikatsu Kaburaki and Makoto Aihara Tags: Research Source Type: research
C-type lectins and extracellular vesicles in virus-induced NETosis
Dysregulated formation of neutrophil extracellular traps (NETs) is observed in acute viral infections. Moreover, NETs contribute to the pathogenesis of acute viral infections, including those caused by the den... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - June 11, 2021 Category: Biomedical Science Authors: Pei-Shan Sung and Shie-Liang Hsieh Tags: Review Source Type: research
