Analysis of the Effectiveness of the Latest 4th Generation Cryoballoon Catheters in Pulmonary Vein Isolation Using High-Resolution Mapping
CONCLUSION: The utility of additional high-density mapping, facilitated by the HD Grid catheter following PVI with the fourth-generation cryoballoon catheter do not substantiate a discernible advantage over conventional mapping methodologies, particularly the spiral mapping catheter. Residual carinal conduction was observed in a substantial cohort of patients (48%), highlighting a persistent challenge in achieving complete electrical isolation.PMID:38663567 | DOI:10.1016/j.hjc.2024.04.006 (Source: Hellenic Journal of Cardiology)
Source: Hellenic Journal of Cardiology - April 25, 2024 Category: Cardiology Authors: Charis Gkalapis Konstantinos Vlachos Marios Papadakis Nikonas Pavleros Hans-J örg Hippe Karim Benali George Bazoukis Konstantinos P Letsas Antonio Frontera Pierre Jais Michael Gotzmann Source Type: research
Impact of abdominal compression on heart and stomach motion for stereotactic arrhythmia radioablation
CONCLUSIONS: AC was not a consistent motion management method for STAR, nor does not uniformly affect the separation distance between LVCs and the stomach. If AC is employed in future STAR protocols, the motion of the target volume and its relative distance to the stomach should be compared on two 4DCTs: one while the patient is FB and one under AC.PMID:38661250 | DOI:10.1002/acm2.14346 (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - April 25, 2024 Category: Information Technology Authors: Daniel David Cecchi Nicolas Paul Ploquin Salman Faruqi Hali Morrison Source Type: research
Right ventricular preload and afterload challenge induces contractile dysfunction and arrhythmia in isolated hearts of dystrophin ‐deficient male mice
AbstractDuchenne muscular dystrophy (DMD) is an X-linked recessive myopathy due to mutations in the dystrophin gene. Diaphragmatic weakness in DMD causes hypoventilation and elevated afterload on the right ventricle (RV). Thus, RV dysfunction in DMD develops early in disease progression. Herein, we deliver a 30-min sustained RV preload/afterload challenge to isolated hearts of wild-type (Wt) and dystrophic (Dmdmdx-4Cv) mice at both young (2 –6 month) and middle-age (8–12 month) to test the hypothesis that the dystrophic RV is susceptible to dysfunction with elevated load. Young dystrophic hearts exhibited greater p...
Source: Physiological Reports - April 25, 2024 Category: Physiology Authors: Andrew Behrmann,
Jessica Cayton,
Matthew R. Hayden,
Michelle D. Lambert,
Zahra Nourian,
Keith Nyanyo,
Brooke Godbee,
Laurin M. Hanft,
Maike Krenz,
Kerry S. McDonald,
Timothy L. Domeier Tags: ORIGINAL ARTICLE Source Type: research
Challenges in Ventricular Arrhythmia Ablation: Difficult Substrates and Advanced Ablation Strategies
This article provides a brief overview of difficult substrate ablation strategies in patients with premature ventricular contractions (PVC) or ventricular tachycardia (VT) and explores methods to improve outcomes for cases that do not respond to typical ablation techniques.Recent findingsRecent developments highlight the crucial role of advanced imaging and mapping techniques in the visualization, characterization, and localization of challenging ventricular substrates. Additionally, some novel and advanced ablation strategies may be useful when PVC/VT is refractory to conventional ablation treatment.SummaryAn expanding sp...
Source: Current Treatment Options in Cardiovascular Medicine - April 25, 2024 Category: Cardiology Source Type: research
Exercise intolerance in a man with ischaemic cardiomyopathy and biventricular pacing
Clinical introduction A patient in his 60s with a history of ischaemic cardiomyopathy and severely reduced left ventricular ejection fraction of 20% presents with worsening dyspnoea on exertion. He is tolerating therapeutic doses of guideline-directed medical therapy including sacubitril-valsartan, carvedilol, spironolactone and empagliflozin, and has a biventricular implantable cardiac defibrillator. He undergoes cardiopulmonary exercise testing (CPET) using the treadmill-modified Bruce protocol and is found to have a severely reduced peak oxygen consumption (VO2) (14.9 mL/kg/min) despite maximal effort. The test was stop...
Source: Heart - April 25, 2024 Category: Cardiology Authors: Bevan, G. H., Buber, J. Tags: Arrhythmias and sudden death Source Type: research
Birth cohort effects on diagnosed atrial fibrillation incidence: nationwide cohort study from 1980 to 2018
Conclusion
Substantial birth cohort effects, independent of age and calendar period, influence trends in diagnosed AF incidence. (Source: Heart)
Source: Heart - April 25, 2024 Category: Cardiology Authors: Vinter, N., Cordsen, P., Johnsen, S. P., Benjamin, E. J., Frost, L., Trinquart, L. Tags: Arrhythmias and sudden death Source Type: research
Heightened long-term cardiovascular risks after exacerbation of chronic obstructive pulmonary disease
Conclusion
Moderate and severe COPD exacerbations are independent risk factors for adverse CV events, especially HF decompensation. The impact of optimising COPD management on CV outcomes should be evaluated. (Source: Heart)
Source: Heart - April 25, 2024 Category: Cardiology Authors: Hawkins, N. M., Nordon, C., Rhodes, K., Talukdar, M., McMullen, S., Ekwaru, P., Pham, T., Randhawa, A. K., Sin, D. D. Tags: Open access Cardiac risk factors and prevention Source Type: research
Therapeutic Hypothermia Compared with Normothermia in Adults with Traumatic Brain Injury; Functional Outcome, Mortality, and Adverse Effects: A Systematic Review and Meta-Analysis
ConclusionsWith the addition of several recent randomized clinical trials and a thorough quality assessment, we have provided an updated systematic review and meta-analysis that concludes that TH does not show any benefit over normothermia in terms of mortality and functional outcome. (Source: Neurocritical Care)
Source: Neurocritical Care - April 25, 2024 Category: Neurology Source Type: research
Apnea Testing on Conventional Mechanical Ventilation During Brain Death Evaluation
ConclusionsApnea testing on conventional mechanical ventilation is feasible and offers several potential advantages over other techniques. (Source: Neurocritical Care)
Source: Neurocritical Care - April 25, 2024 Category: Neurology Source Type: research
Epidemiology of perioperative RV dysfunction: risk factors, incidence, and clinical implications
AbstractIn this edition of the journal, the Perioperative Quality Initiative (POQI) present three manuscripts describing the physiology, assessment, and management of right ventricular dysfunction (RVD) as pertains to the perioperative setting. This narrative review seeks to provide context for these manuscripts, discussing the epidemiology of perioperative RVD focussing on definition, risk factors, and clinical implications. Throughout the perioperative period, there are many potential risk factors/insults predisposing to perioperative RVD including pre-existing RVD, fluid overload, myocardial ischaemia, pulmonary embolis...
Source: Perioperative Medicine - April 25, 2024 Category: Surgery Source Type: research
Challenges in Ventricular Arrhythmia Ablation: Difficult Substrates and Advanced Ablation Strategies
This article provides a brief overview of difficult substrate ablation strategies in patients with premature ventricular contractions (PVC) or ventricular tachycardia (VT) and explores methods to improve outcomes for cases that do not respond to typical ablation techniques.Recent findingsRecent developments highlight the crucial role of advanced imaging and mapping techniques in the visualization, characterization, and localization of challenging ventricular substrates. Additionally, some novel and advanced ablation strategies may be useful when PVC/VT is refractory to conventional ablation treatment.SummaryAn expanding sp...
Source: Current Treatment Options in Cardiovascular Medicine - April 25, 2024 Category: Cardiology Source Type: research
Identification of common mechanisms and biomarkers of atrial fibrillation and heart failure based on machine learning
ConclusionsWe identified four biological markers that are highly correlated with AF and HF, namely,GLUL,NCF2,S100A12, andSRGN. Our findings provide theoretical basis for the clinical diagnosis and treatment of AF and HF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 24, 2024 Category: Cardiology Authors: Zhijun Zhang,
Jianying Ding,
Xiaolong Mi,
Yuanyuan Lin,
Xinjian Li,
Jun Lian,
Jinwen Liu,
Lijuan Qu,
Bingye Zhao,
Xuewen Li Tags: Original Article Source Type: research
A real ‐time signal processing software package for the electrophysiology laboratory
ConclusionWe have developed and demonstrated the feasibility of a readily scalable and open-access Python-based plug in to an electroanatomic mapping system (EnSiteX) to allow real-time processing and display of electrogram (EGM) based information for the procedural electrophysiologist to view intraprocedurally in the electrophysiology laboratory. The availability, to the clinician, of traditional and novel EGM-based metrics at the time of intervention, such as atrial fibrillation ablation, allows for key mechanistic insights into critical unresolved questions regarding arrhythmia mechanism. (Source: Journal of Cardiovascu...
Source: Journal of Cardiovascular Electrophysiology - April 24, 2024 Category: Cardiology Authors: Kathryn D. Tiver,
Campbell Strong,
Dhani Dharmaprani,
Darius Chapman,
Evan Jenkins,
Sobhan Salari Shahrbabaki,
Anand N. Ganesan Tags: BRIEF COMMUNICATION Source Type: research
Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations
AbstractThe limited literature and increasing interest in studies on cardiac electrophysiology, explicitly focusing on cardiac ion channelopathies and sudden cardiac death in diverse populations, has prompted a comprehensive examination of existing research. Our review specifically targets Hispanic/Latino and Indigenous populations, which are often underrepresented in healthcare studies. This review encompasses investigations into genetic variants, epidemiology, etiologies, and clinical risk factors associated with arrhythmias in these demographic groups. The review explores the Hispanic paradox, a phenomenon linking healt...
Source: Journal of Cardiovascular Electrophysiology - April 24, 2024 Category: Cardiology Authors: Sahil Zaveri,
Mohamed Chahine,
Mohamed Boutjdir Tags: REVIEW Source Type: research
Optimal timing of electrical cardioversion for acute decompensated heart failure caused by atrial arrhythmias: The earlier, the better?
AbstractThe optimal timing for electrical cardioversion (ECV) in acute decompensated heart failure (ADHF) with atrial arrhythmias (AAs) is unknown. Here, we retrospectively evaluated the impact of ECV timing on SR maintenance, hospitalization duration, and cardiac function in patients with ADHF and AAs. Between October 2017 and December 2022, ECV was attempted in 73 patients (62 with atrial fibrillation and 11 with atrial flutter). Patients were classified into two groups based on the median number of days from hospitalization to ECV, as follows: early ECV (within 8 days,n = 38) and delayed ECV (9 days or more,n =...
Source: Heart and Vessels - April 24, 2024 Category: Cardiology Source Type: research
