Risk of Cardiovascular Events in Schizophrenic Patients Treated with Paliperidone Palmitate Once-Monthly Injection (PP1M): A Population-Based Retrospective Cohort Study in Taiwan
ConclusionThis study reported the population-based incidence of cardiovascular events in schizophrenic patients initiating PP1M treatment. PP1M was not associated with increased risks of serious cardiovascular events but was potentially associated with lower risks of cardiovascular hospitalizations compared with oral SGAs. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - April 15, 2024 Category: Drugs & Pharmacology Source Type: research
Assessment of Heart Rate Variability in Children with Mitral Valve Prolapse
ConclusionImpaired HRV associated with MVP could be age, gender, and symptom related. In addition, low LF may indicate impaired baroreflex sensitivity in MVP patients. (Source: Mammalian Genome)
Source: Mammalian Genome - April 15, 2024 Category: Genetics & Stem Cells Source Type: research
Mortality and rehospitalization in patients with pre-existing implantable pacemakers undergoing catheter ablation are related to increased comorbidity burden —data from the German Ablation Registry
ConclusionPatients with pacemaker systems undergoing catheter ablation of atrial fibrillation or atrial flutter demonstrate an increased risk of death, cardiovascular events, and re-hospitalization. This observation can be largely attributed to an older patient population and an increased rate of comorbidities. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - April 15, 2024 Category: Cardiology Source Type: research
The role of cardiac magnetic resonance in sports cardiology: results from a large cohort of athletes
ConclusionCMR is more efficient in identifying a pathologic cardiac substrate in athletes in case of VAs (i.e., polymorphic beats), abnormal ECG repolarisation (negative T-waves in inferolateral leads), and borderline echocardiographic findings (LV hypertrophy, mildly depressed LV function). On the other hand, CMR is associated with a large proportion of negative results. Therefore, a careful clinical selection is needed to indicate CMR in athletes appropriately.Graphical AbstractClinical indications for CMR and positive CMR findings.The left panel shows clinical indications for CMR in our athletic cohort and the percentag...
Source: Clinical Research in Cardiology - April 15, 2024 Category: Cardiology Source Type: research
Impact of High-Voltage Device Implantation in Elderly Japanese Patients With Heart Failure as Primary Prevention - Post Hoc Analysis of HINODE
CONCLUSIONS: Although elderly patients may have a higher risk of mortality in general, the benefit of HVD therapy in this group is comparable to that in non-elderly patients.PMID:38616125 | DOI:10.1253/circj.CJ-23-0801 (Source: Circulation Journal)
Source: Circulation Journal - April 14, 2024 Category: Cardiology Authors: Yoshinari Enomoto Takanori Ikeda Keijiro Nakamura Mahito Noro Kaoru Sugi Masao Moroi Masato Nakamura Kengo Kusano Torri Schwartz Torsten Kayser Kazutaka Aonuma Source Type: research
Traditional Chinese medicine injections with Activating Blood Circulation, equivalent effect of anticoagulation or antiplatelet, for acute myocardial infarction: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
CONCLUSION: TCMi-ABC demonstrates additional clinical value in reducing mortality and the risk of malignant arrhythmia in patients with AMI. However, further validation of these findings is warranted through high-quality clinical trials due to methodological weaknesses in randomization, blinding, allocation concealment, and insufficient assessing for the purity/potency of herbs and the gram amount of active constituents.SYSTEMATIC REVIEW REGISTRATION: [INPLASY], identifier [INPLASY202170082].PMID:38616000 | DOI:10.1016/j.ctim.2024.103039 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - April 14, 2024 Category: Complementary Medicine Authors: Xue-Yan Sun Jia-Ping Chen Ju-Ju Shang Hong-Xu Liu Xiang Li Yan Lou Hui-Wen Zhou Source Type: research
Impact of High-Voltage Device Implantation in Elderly Japanese Patients With Heart Failure as Primary Prevention - Post Hoc Analysis of HINODE
CONCLUSIONS: Although elderly patients may have a higher risk of mortality in general, the benefit of HVD therapy in this group is comparable to that in non-elderly patients.PMID:38616125 | DOI:10.1253/circj.CJ-23-0801 (Source: Circulation Journal)
Source: Circulation Journal - April 14, 2024 Category: Cardiology Authors: Yoshinari Enomoto Takanori Ikeda Keijiro Nakamura Mahito Noro Kaoru Sugi Masao Moroi Masato Nakamura Kengo Kusano Torri Schwartz Torsten Kayser Kazutaka Aonuma Source Type: research
Traditional Chinese medicine injections with Activating Blood Circulation, equivalent effect of anticoagulation or antiplatelet, for acute myocardial infarction: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
CONCLUSION: TCMi-ABC demonstrates additional clinical value in reducing mortality and the risk of malignant arrhythmia in patients with AMI. However, further validation of these findings is warranted through high-quality clinical trials due to methodological weaknesses in randomization, blinding, allocation concealment, and insufficient assessing for the purity/potency of herbs and the gram amount of active constituents.SYSTEMATIC REVIEW REGISTRATION: [INPLASY], identifier [INPLASY202170082].PMID:38616000 | DOI:10.1016/j.ctim.2024.103039 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - April 14, 2024 Category: Complementary Medicine Authors: Xue-Yan Sun Jia-Ping Chen Ju-Ju Shang Hong-Xu Liu Xiang Li Yan Lou Hui-Wen Zhou Source Type: research
Impact of High-Voltage Device Implantation in Elderly Japanese Patients With Heart Failure as Primary Prevention - Post Hoc Analysis of HINODE
CONCLUSIONS: Although elderly patients may have a higher risk of mortality in general, the benefit of HVD therapy in this group is comparable to that in non-elderly patients.PMID:38616125 | DOI:10.1253/circj.CJ-23-0801 (Source: Circulation Journal)
Source: Circulation Journal - April 14, 2024 Category: Cardiology Authors: Yoshinari Enomoto Takanori Ikeda Keijiro Nakamura Mahito Noro Kaoru Sugi Masao Moroi Masato Nakamura Kengo Kusano Torri Schwartz Torsten Kayser Kazutaka Aonuma Source Type: research
Traditional chinese medicine injections with activating blood circulation, equivalent effect of anticoagulation or antiplatelet, for acute myocardial infarction: A systematic review and meta-analysis of randomized clinical trials
CONCLUSION: TCMi-ABC demonstrates additional clinical value in reducing mortality and the risk of malignant arrhythmia in patients with AMI. However, further validation of these findings is warranted through high-quality clinical trials due to methodological weaknesses in randomization, blinding, allocation concealment, and insufficient assessing for the purity/potency of herbs and the gram amount of active constituents.SYSTEMATIC REVIEW REGISTRATION: [INPLASY], identifier [INPLASY202170082].PMID:38616000 | DOI:10.1016/j.ctim.2024.103039 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - April 14, 2024 Category: Complementary Medicine Authors: Xueyan Sun Jiaping Chen Juju Shang Hongxu Liu Xiang Li Yan Lou Huiwen Zhou Source Type: research
Carnitine palmitoyltransferase II (CPT II) deficiency responsible for refractory cardiac arrhythmias, acute multiorgan failure and early fatal outcome
Carnitine palmitoyltransferase II (CPT II) deficiency is a rare inborn error of mitochondrial fatty acid metabolism with autosomal recessive pattern of inheritance. Its phenotype is highly variable (neonatal, ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 14, 2024 Category: Pediatrics Authors: Gregorio Serra, Vincenzo Antona, Vincenzo Insinga, Giusy Morgante, Alessia Vassallo, Simona La Placa, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz, Eloisa Gitto, Mario Giuffr è and Giovanni Corsello Tags: Case report Source Type: research
Carnitine palmitoyltransferase II (CPT II) deficiency responsible for refractory cardiac arrhythmias, acute multiorgan failure and early fatal outcome
ConclusionsCPTII deficiency may be suspected in newborns showing cardiac arrhythmias, associated or not with hypertrophic cardiomyopathy, polycystic kidneys, brain malformations, hepatomegaly. Its diagnosis should be even more suspected and investigated in cases of increased plasmatic levels of creatine phosphokinase and acylcarnitines in addition to kidney, heart and liver dysfunctions, as occurred in the present patient. Accurate family history, extended metabolic screening, and multidisciplinary approach are necessary for diagnosis and adequate management of affected subjects. Next generation sequencing (NGS) techniques...
Source: Italian Journal of Pediatrics - April 14, 2024 Category: Pediatrics Source Type: research
Roles of Integrin in Cardiovascular Diseases: From Basic Research to Clinical Implications
Int J Mol Sci. 2024 Apr 7;25(7):4096. doi: 10.3390/ijms25074096.ABSTRACTCardiovascular diseases (CVDs) pose a significant global health threat due to their complex pathogenesis and high incidence, imposing a substantial burden on global healthcare systems. Integrins, a group of heterodimers consisting of α and β subunits that are located on the cell membrane, have emerged as key players in mediating the occurrence and progression of CVDs by regulating the physiological activities of endothelial cells, vascular smooth muscle cells, platelets, fibroblasts, cardiomyocytes, and various immune cells. The crucial role of integ...
Source: Atherosclerosis - April 13, 2024 Category: Cardiology Authors: Shuo Zhang Qingfang Zhang Yutong Lu Jianrui Chen Jinkai Liu Zhuohan Li Zhenzhen Xie Source Type: research
Prevalence and risk evaluation of cardiovascular disease in the newly diagnosed prostate cancer population in China: A nationwide, multi-center, population-based cross-sectional study
CONCLUSIONS: Prostate cancer patients in China are diagnosed at an advanced stage. A heavy CVD burden was present at the initiation of treatment. Patients who accepted ADT-related therapy showed an original higher risk of CVD, but the awareness of cardiovascular protection was far from sufficient.PMID:38613214 | DOI:10.1097/CM9.0000000000003087 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 13, 2024 Category: General Medicine Authors: Weiyu Zhang Huixin Liu Ming Liu Shi Ying Renbin Yuan Hao Zeng Zhenting Zhang Sujun Han Zhannan Si Bin Hu Simeng Wen Pengcheng Xu Weimin Yu Hui Chen Liang Wang Zhitao Lin Tao Dai Yunzhi Lin Tao Xu Source Type: research
Prevalence and risk evaluation of cardiovascular disease in the newly diagnosed prostate cancer population in China: A nationwide, multi-center, population-based cross-sectional study
CONCLUSIONS: Prostate cancer patients in China are diagnosed at an advanced stage. A heavy CVD burden was present at the initiation of treatment. Patients who accepted ADT-related therapy showed an original higher risk of CVD, but the awareness of cardiovascular protection was far from sufficient.PMID:38613214 | DOI:10.1097/CM9.0000000000003087 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 13, 2024 Category: General Medicine Authors: Weiyu Zhang Huixin Liu Ming Liu Shi Ying Renbin Yuan Hao Zeng Zhenting Zhang Sujun Han Zhannan Si Bin Hu Simeng Wen Pengcheng Xu Weimin Yu Hui Chen Liang Wang Zhitao Lin Tao Dai Yunzhi Lin Tao Xu Source Type: research
